Research and development of new diagnostic and therapeutic methodologies

The aims of this course will be to provide an up-date knowledge of technical, novel, emerging basic and translational aspects in the diagnosis and therapeutic approaches in cancer.
In particular, the course will be focused on the available methodologies involving mouse models, organoids, NGS applications the emerging role of non coding RNAs as therapeutic platforms in the context of tumor heterogeneity, the role of tumour molecular profiling in precision oncology, the advance of minimal residual disease approaches in the management of patients in the era of new drugs, and the physical bases and potential applications of the most important imaging techniques for non-invasive tumour biological characterization and its supporting role for tumour treatment and radiotherapeutic approaches.

In particular, by following this course it will be possible to learn about innovative diagnostic and therapeutic approaches based on:
- Techniques and methods for the tumour molecular characterization
- Interpretation of tumour genomic variants and their management in clinical practice.
- The importance of the determination of minimal residual disease
- Imaging techniques for clinical and pre-clinical tumour characterization and treatment.
- Animal models for the development of diagnostic and therapeutic tools