Molecular genetics

This course provides an exhaustive overview of the fundamental principles guiding molecular genetics approaches. Key learning objectives include:
- understanding the concept of inheritance of genetic information and genes action, including dominance, epistasis and their contribution to the manifestation of traits;
- understanding the contribution of transcriptional and post-transcriptional events toward gene expression, and the related techniques/approaches that enable to distinguish between these two processes;
- understanding the strategies and the design of genetic screens, including the use of genetic variability as a means to understand gene regulatory networks.

After this course, the student will be able to:
- critically evaluate and describe hierarchies in gene action and regulation by applying the principles of transmission genetics;
- design genetic experiments as a mean to gain molecular insights into biological processes and support/reject working hypothesis;
- correctly interpret and communicate results pertaining gene regulation under physiological and pathological conditions.