Epigenetics and epigenomics

The Course will provide knowledge to understand the main molecular mechanisms of epigenetic regulation. It will explore aspects of epigenomics, with specific reference to the molecular bases of regulation of gene expression and association with the development of tissues in mammals and plants. The course will highlight diverse aspects of epigenetics, including transcriptional regulation, chromatin biology, chromosome topology and current research in cell reprogramming, genome function and organization.

Upon completion of this course, students will be able to:
1. Comprehend the definition of epigenetics and recognize and analyze various epigenetic phenomena.
2. Outline the major epigenetic mechanisms with respect to their link to RNA transcription and DNA replication and organization.
3. Know and apply current techniques developed to study epigenetics and epigenomes.
4. Appreciate the role of epigenetic regulation in normal development and in stress/disease conditions.