Biotechnological and molecular strategies in the control of parasites and vector-borne pathogens

This course aims mainly to provide theoretical bases for improvement and management of biotechnological processes and the use of enzymes technology for production of compounds by industrial bioprocesses. The course is ideally linked to those dealing with protein engineering, structural biology, enzymology, bioinformatics.

At the end of this class, the students are expected to:
1) have acquired understanding of importance of metabolic pathways on process development;
2) have understood the rational of metabolic engineering strategies (approaches and methods) utilized to improve cellular performance;
3) have acquired understanding of theoretical aspects and experimental approaches to engineer microorganisms in the context of biotechnological applications;
4) be able to recognize some relevant applications of free or immobilized enzymes for the biotransformations of both natural and non-natural substrates in terms of enzymes involved, products obtained and operational details.
5) have acquired the ability to correlate the disciplines involved and their relevance to biotechnological developments.