Research Centres (CRC)

The centre is an incubator and accelerator for the development of innovative technological solutions to overcome the main challenges still remaining in the creation of organoids.

Organoids are the most innovative methods available to medical research for studying various mechanisms outside the body:

• disease mechanisms
• response to drugs including side-effects
• interactions between different cell components, such as those of tumours and the immune system.

Although organoids now occupy a central position in biomedicine, making their use accessible on a large scale in order to exploit their full potential still poses technological challenges.

The centre aims to consolidate and expand the network of scholars of Byzantium and its literary, historiographic, linguistic and artistic manifestations.

It can link scholars of topics related to Byzantium in the broadest sense, such as:

• the forerunners of Byzantine literary and artistic culture in ancient Greece and Imperial/late ancient Rome
• links between the Byzantine East and the medieval Latin and romance West
• the heritage of Byzantium in the history of western European culture since Humanism.

Il CRC Cardano prosegue e amplia l’orizzonte cronologico e tematico del ‘Progetto Cardano’, nato nel 1995 sotto la direzione di Marialuisa Baldi e Guido Canziani e trasferito nel 2007 dal CNR all’Università degli Studi di Milano.

Il Centro si costituisce come un punto d’incontro sinergico tra le competenze disciplinari dei docenti e dei dipartimenti dell’Università di Milano suoi membri, che cooperano allo scopo di promuovere lo studio di Girolamo Cardano, del suo ambiente culturale, e in generale del Rinascimento lombardo tra i secoli XIV e XVII—forse il più trascurato tra i ‘Rinascimenti’ italiani.
Il centro rappresenta un unicum nel panorama nazionale, che già vede centri di ricerca per lo studio del rinascimento toscano, romano, veneziano, e meridionale.

The centre aims to improve health by sharing information emerging and developing in research laboratories and study groups.

It is an innovative model of collaborative research between researchers in the fields of infectious diseases, microbiology and immunology according to a modern conception of world health.

Research activities build a continuum between the various branches of science, from basic to operative, directed at health policy.

The aim of the centre is to contribute to progress in international understanding through clinical and translational research, optimizing and/or activating collaborations between research groups.

The main lines of research of the centre are:

• the donor-recipient relationship

• the impact of antiviral treatments before and after transplant in patients with HBV and HCV

• long-term metabolic complications in liver transplant patients.

The aim of the research centre is to become a national and international reference point in health administration training and research:

• health management

• public health

• law

• clinical governance and leadership

• health policy.

It brings together interdisciplinary and multiprofessional research interests across departments in order to contribute to the development and dissemination of new competences, instruments and management practices. These will enable company managers, experts, institutions and firms involved in healthcare to operate sustainably and produce maximum value for users of health and social services.

Lino Rossi research centre was established in 2004 by the University of Milan "La Statale" for the study and prevention of sudden and unexpected death of unborn babies and those under one year of age.

As Centre of Reference for application of Law no 31/2006 regarding the diagnostic data of victims of SIDS and sudden fetal death, it has been recognized by the Ministry of Health as the National Data Base that receives the clinical, epidemiological and diagnostic data of all cases of sudden fetal or infantile death occurring in the different regions of Italy.

With this large statistical sample, unique in the world, the centre has conducted various studies, especially in the field of neuropathology, many of which have been published in international journals.

The centre is concerned with scientific research in the sector of rare clotting disorders, both haemorrhagic and thrombotic.

Its activities focus on standardization of laboratory methods for assessing alterations in haemostatic balance and the search for genetic mutations causing haemophilia and thrombophilia in order to identify the best therapies for these syndromes.

The Center aims to study and implement innovative clinical research models focused on chronic-degenerative diseases and rehabilitation models, with a focus on head and neck pathology. Research is geared towards the development of new approaches for translational studies, observational studies on patients and clinical trials. Research activities, linking pre-clinical trials with clinical practice and strategies for public health, consider translational and clinical studies as a unique two-way process based on a highly multidisciplinary approach integrating basic research, clinical research, clinical practice, and population studies.

The centre has been operative at the Niguarda Ca’ Granda hospital in Milan since 1972, conducting studies and research on:

• physiopathology of lipid transport in humans
• hereditary lipoprotein profile anomalies
• mechanism and clinical efficacy of pharmacological treatments, functional foods and nutraceutics in dyslipidaemic patients.

The centre aims to provide a necessary alternative message on the topic of health with respect to the proliferation of mass media messages, and to meet the growing demand by citizens for health and empowerment.

Research:

• elaboration of content (texts and videos) from the scientific literature to communicate arguments regarding health that are topical, concern research and are of public interest or of interest to healthcare workers

• reply to national and international research calls on relevant topics

• organisation of conferences/workshops for specific targets (healthcare workers, patients' associations) in collaboration with sustaining bodies

• courses of continuing education on correct and effective communication regarding health for journalists and/or healthcare workers

• drafting of scientific articles on communication of questions regarding drugs, health and society.

The centre conducts and promotes study, research, conferences and publications on the figure of Giovanni Battista Pergolesi and more generally on Italian eighteenth century vocal and instrumental music.

Its institutional aims include:

• to promote research on the life and work of Pergolesi, the Neapolitan cultural and musical context and Italian eighteenth century music

• to collect (originals, copies, electronic formats), catalogue and check the authenticity of documentary, musical, literary and iconographic sources regarding the composer

• to provide documentary and scientific support for the National Edition of the Works of Giovanni Battista Pergolesi, instituted in 2009 by the Ministry for Cultural Heritage and Activities

• to promote conferences, study groups, seminars and scientific publications; to collaborate with research centres and institutions that organise conferences and exhibitions and with theatre and concert organisations that plan the preparation and public performance of the works of Pergolesi.

CERIDAP is a place for in-depth study and research on Public Administration, with a view to "good administration". The Center interacts with Italian and European public and private institutions that are interested in these issues.

The centre is an Italian and international reference point for the study of acute respiratory insufficiency. It hosts all the clinical figures necessary for the care of patients with this pathology: anaesthetists, intensive care specialists and pneumologists.

The doctors have long experience and work with the major university hospitals of Milan:

• ASST Santi Paolo e Carlo

• Fondazione IRCCS Ca’ Granda

• ASST Sacco Buzzi Fatebenefratelli.

The CARC Centre of the University of Milan promotes studies and analyzes the linguistic, cultural, economic, legal, political and social realities of contemporary Asian countries, with an interdisciplinary approach based on the constant and rigorous examination of sources in original languages.

Heir of a previous interdepartmental research center, founded in 2005, CARC enjoys consolidated international relations and represents a meeting place for different research groups which study contemporary Asia using different methodological and scientific approaches.

The aim of the centre is to create a new group within the University for the study of:

• emerging properties of complex biological and bio-mimetic materials

• how cell and elementary biomolecular processes become part of complex regulatory networks that give rise to disease.

The aim of the centre is to provide a platform for operators in the sector that promotes adoption of international standards of measurement.

It is aimed at:

• diagnostic industries

• clinical laboratories and other bodies.

Il Centro nasce dalla collaborazione fra sei Unità di ricerca UNIMI operative da diversi anni nell'ambito dell’analisi tossicologica in differenti ambiti:

• Laboratorio di Tossicologia Forense del Dipartimento di Scienze Biomediche, Chirurgiche ed Odontoiatriche
• Laboratorio di Analisi Chimico - Tossicologica del Dipartimento di Scienze Farmaceutiche
• Laboratorio di Drug discovery and manufacturing development del Dipartimento di Scienze Farmaceutiche
• Laboratorio di Analisi Farmaceutica e Biofarmaceutica del Dipartimento di Scienze Farmaceutiche Dipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche Direttore: Prof. Aldo Bruno Giannì
• Laboratorio di Biochimica Clinica e Spettrometria di Massa del Dipartimento di Scienze della Salute
• Sezione ‘One Health’ del Dipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche

Queste Unità di ricerca hanno competenze e professionalità sinergiche e complementari per quanto riguarda la analisi di sostanze tossiche di varia origine e droghe d’abuso dal punto di vista chimico, biochimico-metabolico e alimentare-ambientale.
Il CRC ha come finalità il potenziamento sia delle attività produttive che di ricerca nell’ambito della Tossicologia Analitica (TA), una disciplina che ogni giorno viene citata per risolvere casi giudiziari ma che, in modo particolare, è uno strumento indispensabile per prevenire la diffusione di sostanze pericolose per la salute ed individuare gli effetti deleteri che possono produrre.

L'attivazione del CIRS “Marcello Marchetti” rappresenta un unicum nel contesto italiano e uno tra i pochi in ambito europeo. Il centro combina competenze in diritto farmaceutico e scienze regolatorie con conoscenze scientifiche e tecnologiche ed è finalizzato a fornire servizi regolatori rivolti sia ai docenti del nostro Ateneo sia a soggetti esterni. 

Le tematiche di ricerca e di servizio del CISR comprendono l’analisi dei requisiti tecnici relativi alla qualità, della sicurezza e dell'efficacia dei medicinali, comprese per terapie avanzate (ATMP) e farmaci a RNA, ovvero di dispositivi medici, prodotti cosmetici, integratori alimentari e altri prodotti salutistici.

La medicina di precisione si propone di sartorializzare l’approccio al paziente prescrivendo il farmaco più adeguato per garantire la migliore risposta minimizzando la possibilità di esperire effetti collaterali. Pertanto l’acquisizione di dati rappresentativi della popolazione generale (big data) e la loro elaborazione (statistica convenzionale & machine learning) porta al riconoscimento di gruppi di pazienti (clusters) con caratteristiche cliniche, demografiche, sociali e biologiche capaci di prevedere la risposta ad un dato farmaco già al baseline

La costituzione in UNIMI del primo centro di medicina di precisione dedicato all’infiammazione cronica  mira ad ottimizzare le risorse per svolgere una ricerca di frontiera e traslazionale che possa portare le scoperte scientifiche direttamente ed in modo pragmatico nella pratica clinica, in linea con i principi di One health e del PNRR.

Il CRC rappresenta lo strumento attraverso il quale coordinare e sviluppare i percorsi di ricerca sui temi oggetto di attività delle cliniche legali.
Le Cliniche legali sono attività didattiche imperniate sulla metodologia del learning by doing e si caratterizzano per il fatto di operare sul territorio mettendo a disposizione risorse e competenze negli ambiti oggetto di interesse. Costituiscono uno strumento prezioso per individuare e tematizzare questioni di rilevanza ed attualità sul terreno della sostenibilità e dell’accesso ed efficienza della giustizia.

Il CRIMePO  si propone come punto di riferimento nazionale e internazionale nel campo della ricerca in ambito criminologico e politico-criminale con l’intento:

• di promuovere lo studio interdisciplinare della questione criminale nelle sue molteplici declinazioni e delle politiche pubbliche nel campo della giustizia penale, della sicurezza, delle polizie, e della giustizia di transizione
• di far progredire la criminologia come campo di ricerca transdisciplinare, luogo di confine in cui le diverse forme della conoscenza (scientifica, filosofica, storica, letteraria) concorrono a mettere a fuoco temi, approcci e percorsi di studio
• di incoraggiare, in particolare, l’incontro tra la ricerca criminologica e settori di studi solitamente poco esplorati dai criminologi ma decisivi nel costruire conoscenze criminologico-politiche (come ad esempio i conflict and democracy studies, i peace studies, i social justice studies)
• di coinvolgere decisori politici, esperti, operatori, organizzazioni, società civile e destinatari finali per co-produrre un sapere criminologico-politico capace di orientare l’elaborazione di iniziative, progetti, programmi e leggi

The Centre advances research in the field of neurology. Its strategy is based on the close integration of clinical aspects of diagnosis and treatment of neurological diseases with basic research on aetiopathogenetic events and, above all, experimental therapeutics.

The aim of the Data Science Research Centre (DSRC) is to integrate local competence and research activity in the fields of computer science and statistics. The primary objective is to develop novel approaches to smart processes based on the analysis of large, heterogeneous data.

In particular, DSRC promotes Data Science as critical to a shared and unified approach to coming cultural, scientific and social challenges.

For these reasons, the DSRC intends to involve and enhance the University’s very rich and diverse disciplinary capacities, ranging from the social sciences to the humanities, from the life sciences to medicine, by promoting their interaction.

GAIA-2050 studies the relationships between environmental change and health risk, and not solely with regard to the effects of pollution. It does so through collaboration and synergies between scholars in different scientific disciplines, such as: Environmental Health, Landscape Ecology, Food Health, Agroecology, Environmental Economics, Systemic Health and networks healthcare.

It promotes scientific collaboration between academics from university departments, nationally and internationally, on issues of environmental sustainability sciences and policies, also with regard to the economy.

The Centre aims to constitute a point of reference for scientific research and to deepen interdisciplinary understanding of the new forms taken by the rights of the defence as a result of changes in law and European jurisprudence on criminal proceedings.

The activities of the centre are:

• publication;

• research projects;

• training activity;

• exchange of personnel between universities and other European institutions.

The Centre aims to consolidate collaboration between literary studies and geography, opening it up to foreign scholars and institutions outside the University.

The intersection between the two disciplines is critically important to the interdisciplinary and intertextual fabric of contemporary culture, though the two disciplines are deeply linked and have been in dialogue with each other since Antiquity. If geography acknowledges the inescapable presence within itself of a subjective and imaginative element, literature cannot fail to recognize the crucial role of geography in textual, poetic and narrative production.

The meeting point between the two disciplines is located in the multiple modes of perception and representation of space, the primary dimension of our experience. Equally important is its imaginative role. The intersections between the materiality and the metaphorical representation of natural environments also highlight its archetypal quality. Islands, rivers, seas, forests, mountains, deserts are not only physical and geographical entities, but also cultural structures and mental constructs.

Gesdimont aims to test and promote methodological innovation and operations specific to the complex characteristics and needs of mountainous areas identified in the course of research, and the transfer of technologies strategic for the socio-economic development of such areas.

The Centre for Renal Immunopathology proposes to bring together academics from different departments who share an interest in renal immunopathology.

The Centre’s aim is to provide expertise in different aspects of the pathology and to promote among third parties the adoption of specific lines of research into these aspects.

The Centre was designed as a control room for law and science research and initiatives, and as a link between expert researchers in law, biology, chemistry, agricultural and environmental studies, in order to promote technological innovation at the service of public health, food and sustainable development.

The Centre will focus on specific issues: human rights, climate and environmental change, health and big data, nutrition in the context of health, law and the market, mass spectrometry applied to behaviour (relationship between behaviour and pollution), GMO and access to water.

The Centre was created to establish an interdisciplinary network of skills and a critical mass of knowledge, instruments and human resources sufficient to enhance the University’s capacities in the field of polymeric materials. This serves to structure training and research in the material and polymer sciences, both inside and outside the University.

The Centre aims to operate widely across the field of material and polymer sciences, focusing on many sectors of application, at both the basic and advanced research levels.

The Centre coordinates interdisciplinary research aiming to understand the most important features of the link between reading and the formation of the person: ‘I read, therefore I am’ expresses a tradition and a cultural reality whose significance contemporary society would seem to underestimate.

The centre aims to further develop an extant network of relations with other reading studies centres, at home and abroad.

Immuno-mediated inflammatory diseases (IMID) such as chronic intestinal inflammatory diseases (MICI; in English, IBD), Crohn's disease (MC) and ulcerative colitis (CU), rheumatoid arthritis, spondyloarthopathies, lupus erythematosus (LES), uveitis, iridocyclitis, multiple sclerosis, psoriasis, etc. are a group of poorly understood pathological conditions, which are characterized by common inflammatory pathways determining the inflammation itself and are the result of alterations of normal immune responses and their regulation.

Although their aetiology is unknown, IMIDs are understood as resulting from a complex interaction between environmental, genetic, immune, inflammatory and microbial factors. The Centre has as its main objective the study of these interactions. The aim is to advance a multidisciplinary approach to the underlying pathogenetic mechanisms as a basis for the development and improvement of diagnostic and therapeutic models.

The Centre acts as proponent and interlocutor for the development of national and international collaborative networks to promote multicentred studies that will allow:

• the enlistment of large patient cohorts;

• the testing of new drugs, with potential implications for the industry;

• the pursuit of preclinical scientific research validated in clinical settings, improving success rates in securing European funding for related research projects.

The Centre studies the fashion and consumer sector, and aims to promote:

• scientific initiatives such as conferences and seminars;

• the study and acquisition of telematic archives and libraries;

• the promotion of exhibitions and shows.

The CRC uses a multidisciplinary approach to coordinate legal, scientific, humanistic, historical and sociological competences on issues related to migration and the protection of migrants' rights, such as:

• the integration of foreigners,
• the constitutional right of asylum,
• the protection of migrants' cultures,
• new forms of slavery,
• the right to healthcare,
• the identification of new migrants,
• fragility assessments in the review of applications for international protection,
• the rights of migrant women who have suffered torture and/or violence.

The Centre aims to carry out transversal projects, which will integrate research groups, their skills, tools and laboratories to increase the level of research.

This integration is already underway through funded projects that have been recently completed or are currently in progress. The collaborating parties have also developed several projects that are currently under review.

The Centre promotes three specific lines of paediatric research:

• type I diabetes, aiming to identify its genetic causes, its prevention, the development of cell therapy and the prevention/reduction of complications;

• pharmacological studies of the paediatric patient that will answer the currently limited, specific understanding of mechanisms of action, efficacy, safety and the dosage of drugs;

• the application of developments in metabolomics in the screening, diagnosis and monitoring of rare metabolic diseases, and the development of genomic strategies for the screening and diagnosis of hereditary diseases, including rare endocrine-metabolic pathologies.

The PhilTech@UNIMI Research Center is a strategic initiative of excellence in multi- and inter-disciplinary research in the field of Philosophy of Technology within the Department of Philosophy of the University of Milan.

It constitutes a key facility within the new Departmental Excellence Project Techne (2023-2028).

The Centre was created to restore understanding of the history and culture of Etruscan Tarquinia, one of the most important cities of Antiquity (UNESCO 2004).

The Centre’s goal is to facilitate transitions from the visibility of the archaeological materials to the invisibility of the culture and history of an ancient city, without recourse to either pre-established models or literary sources.

The Centre promotes research on romantic and late-romantic thinking.

The Centre advances synergies between those departments where research has been carried out on the teaching of Italian L1/L2 and its methods, and on the history of teaching and learning of Italian L2 /as foreign language in Europe and the rest of the world. It also examines the contemporary neo-multilingual context and considers research experience in adjacent fields. The aim is to advance knowledge relating to the history of theories and language teaching practices for Italian L1/L2 and to integrate endeavours that bring interlinguistics research to bear on these areas.

The Centre consolidates experience acquired over the past few years, aiming to deepen biological understanding of MSCs, advance technological and clinical development in the field of cellular therapies, and to test safety.

The Centre will help to better match research with external stakeholders and funders, by pursuing basic, preclinical and clinical studies of mesenchymal stem cells, aiming to create products for advanced human and veterinary therapy without having to destroy human embryos.

The Centre aims to:

• spread across Italy knowledge of the economic, social, political, cultural and religious history of Switzerland and in particular of Italian Switzerland;

• foster relations between Italian scholars studying the history of Switzerland and exchanges between Italian and Swiss universities and scholars;  

• promote research, doctoral theses and undergraduate dissertations on Swiss history and concerning the relations between Switzerland and Italy;

• promote the implementation of training and further training activities relating to Swiss history and culture, both for registered students and for external audiences.

La ricerca sul pensiero antico della Statale è caratterizzata da una forte e assai proficua relazione tra storiografia filosofica, filologia classica e studio della letteratura greco-latina. La crescente specializzazione degli studi classici ha reso sempre più importante la cooperazione tra ricercatori con competenze differenti, anche se fortemente interconnesse.

Il Centro di Studi mira non solo a istituzionalizzare i rapporti scientifici già in essere, ma ad ampliare le aree di competenza, con particolare riferimento ad Aristotele, la tradizione aristotelica e la filosofia latina. Come anche l’ultimo QS Ranking mostra, gli studi classici e filosofici del nostro Ateneo godono di buona reputazione internazionale: il Centro si propone di promuoverla ulteriormente attraverso nuove edizioni critiche, pubblicazioni, convegni, e il consolidamento di network con centri e gruppi di ricerca analoghi, nazionali e internazionali. Il Centro si propone inoltre di organizzare iniziative didattiche di alta specializzazione per studenti del nostro e di altri Atenei, come una Summer School di Filologia Filosofica a Palazzo Feltrinelli, e laboratori di filologia filosofica, da svolgersi anche presso la Biblioteca Ambrosiana. Il Centro rappresenta il quadro di riferimento per alcune delle attività dei visiting professors invitati dai Dipartimenti di afferenza dei componenti.

The Centre is active in the field of diagnostic and preclinical imaging with infrared thermography and optical molecular imaging (bioluminescence and fluorescence).

The purpose of the Centre is to enhance, strengthen and extend existing scientific and clinical collaboration with laboratories and other research bodies, both public and private, with the local health and social partners affiliated with the University of Milan, and with various corporate actors in the sector, national and multinational.

La missione del centro è contribuire allo sviluppo e diffusione di nuove applicazioni, modelli di servizio e competenze che consentano ai professionisti (studenti in medicina e medici già operanti nel SSN) e ai manager di istituzioni ed imprese pubbliche e private che a diverso titolo sono attive nel settore della salute, di introdurre e gestire nel tempo l’innovazione tecnologica e la telemedicina garantendone sostenibilità e generando il massimo valore per tutti gli stakeholder.

Nel panorama italiano e internazionale il CRC assume un posizionamento competitivo che lo distingue e differenzia in modo significativo, forte di una multidisciplinarietà (che comprende medicina, fisica, informatica, economia e management, diritto) centrale per affrontare le sfide che l’innovazione tecnologica pone per una sanità sempre più inclusiva e sostenibile.

The Centre aims to offer:  

• international visibility to the university as a reference point for the assessment of toxicological risk in various areas of production;

• scope for undergraduate dissertations in the field of toxicological risk assessment and internships for recent graduates.