Molecular and Cellular Biology
Doctoral programme (PhD)
A.Y. 2024/2025
Study area
Science and Technology
PhD Coordinator
The doctoral programme aims to:
- train scientific experts with excellent skills in the field of biomolecular sciences and biotechnology;
- promote a molecular approach to the study of complex biological problems in model organisms (prokaryotic and eukaryotic microorganisms, animals and plants);
- encourage collaboration between research institutes, advanced training schools and companies in the fields of biomolecular sciences and biotechnology;
- encourage internationalisation by promoting international scientific collaborations, involving foreign lecturers, recruiting postgraduate students from abroad, and organising co-tutored dissertations involving study periods abroad.
Training activities will be characterised by:
- a multidisciplinary approach;
- interactivity;
- links to the business world;
- internationalisation.
A key element of the programme is the direct involvement of doctoral students in experimental research activities. Students will work full-time on a research project, providing critical insight and suggestions, and thereby acquiring scientific and organisational independence.
- train scientific experts with excellent skills in the field of biomolecular sciences and biotechnology;
- promote a molecular approach to the study of complex biological problems in model organisms (prokaryotic and eukaryotic microorganisms, animals and plants);
- encourage collaboration between research institutes, advanced training schools and companies in the fields of biomolecular sciences and biotechnology;
- encourage internationalisation by promoting international scientific collaborations, involving foreign lecturers, recruiting postgraduate students from abroad, and organising co-tutored dissertations involving study periods abroad.
Training activities will be characterised by:
- a multidisciplinary approach;
- interactivity;
- links to the business world;
- internationalisation.
A key element of the programme is the direct involvement of doctoral students in experimental research activities. Students will work full-time on a research project, providing critical insight and suggestions, and thereby acquiring scientific and organisational independence.
Classi di laurea - Classes of master's degrees:
LM-6 Biologia,
LM-7 Biotecnologie agrarie,
LM-8 Biotecnologie industriali,
LM-9 Biotecnologie mediche, veterinarie e farmaceutiche,
LM-11 Conservazione e restauro dei beni culturali,
LM-13 Farmacia e farmacia industriale,
LM-17 Fisica,
LM-18 Informatica,
LM-21 Ingegneria biomedica,
LM-22 Ingegneria chimica,
LM-25 Ingegneria dell'automazione,
LM-31 Ingegneria gestionale,
LM-32 Ingegneria informatica,
LM-35 Ingegneria per l'ambiente e il territorio,
LM-40 Matematica,
LM-41 Medicina e chirurgia,
LM-42 Medicina veterinaria,
LM-44 Modellistica matematico-fisica per l'ingegneria,
LM-46 Odontoiatria e protesi dentaria,
LM-47 Organizzazione e gestione dei servizi per lo sport e le attività motorie,
LM-48 Pianificazione territoriale urbanistica e ambientale,
LM-51 Psicologia,
LM-52 Relazioni internazionali,
LM-53 Scienza e ingegneria dei materiali,
LM-54 Scienze chimiche,
LM-56 Scienze dell'economia,
LM-58 Scienze dell'universo,
LM-59 Scienze della comunicazione pubblica, d'impresa e pubblicità,
LM-60 Scienze della natura,
LM-61 Scienze della nutrizione umana,
LM-67 Scienze e tecniche delle attività motorie preventive e adattate,
LM-68 Scienze e tecniche dello sport,
LM-69 Scienze e tecnologie agrarie,
LM-70 Scienze e tecnologie alimentari,
LM-71 Scienze e tecnologie della chimica industriale,
LM-73 Scienze e tecnologie forestali ed ambientali,
LM-74 Scienze e tecnologie geologiche,
LM-75 Scienze e tecnologie per l'ambiente e il territorio,
LM-76 Scienze economiche per l'ambiente e la cultura,
LM-78 Scienze filosofiche,
LM-79 Scienze geofisiche,
LM-82 Scienze statistiche,
LM-86 Scienze zootecniche e tecnologie animali,
LM-91 Tecniche e metodi per la società dell'informazione,
LM-92 Teorie della comunicazione,
LM/SNT1 Scienze infermieristiche e ostetriche,
LM/SNT2 Scienze riabilitative delle professioni sanitarie,
LM/SNT3 Scienze delle professioni sanitarie tecniche,
LM/SNT4 Scienze delle professioni sanitarie della prevenzione
LM-6 Biologia,
LM-7 Biotecnologie agrarie,
LM-8 Biotecnologie industriali,
LM-9 Biotecnologie mediche, veterinarie e farmaceutiche,
LM-11 Conservazione e restauro dei beni culturali,
LM-13 Farmacia e farmacia industriale,
LM-17 Fisica,
LM-18 Informatica,
LM-21 Ingegneria biomedica,
LM-22 Ingegneria chimica,
LM-25 Ingegneria dell'automazione,
LM-31 Ingegneria gestionale,
LM-32 Ingegneria informatica,
LM-35 Ingegneria per l'ambiente e il territorio,
LM-40 Matematica,
LM-41 Medicina e chirurgia,
LM-42 Medicina veterinaria,
LM-44 Modellistica matematico-fisica per l'ingegneria,
LM-46 Odontoiatria e protesi dentaria,
LM-47 Organizzazione e gestione dei servizi per lo sport e le attività motorie,
LM-48 Pianificazione territoriale urbanistica e ambientale,
LM-51 Psicologia,
LM-52 Relazioni internazionali,
LM-53 Scienza e ingegneria dei materiali,
LM-54 Scienze chimiche,
LM-56 Scienze dell'economia,
LM-58 Scienze dell'universo,
LM-59 Scienze della comunicazione pubblica, d'impresa e pubblicità,
LM-60 Scienze della natura,
LM-61 Scienze della nutrizione umana,
LM-67 Scienze e tecniche delle attività motorie preventive e adattate,
LM-68 Scienze e tecniche dello sport,
LM-69 Scienze e tecnologie agrarie,
LM-70 Scienze e tecnologie alimentari,
LM-71 Scienze e tecnologie della chimica industriale,
LM-73 Scienze e tecnologie forestali ed ambientali,
LM-74 Scienze e tecnologie geologiche,
LM-75 Scienze e tecnologie per l'ambiente e il territorio,
LM-76 Scienze economiche per l'ambiente e la cultura,
LM-78 Scienze filosofiche,
LM-79 Scienze geofisiche,
LM-82 Scienze statistiche,
LM-86 Scienze zootecniche e tecnologie animali,
LM-91 Tecniche e metodi per la società dell'informazione,
LM-92 Teorie della comunicazione,
LM/SNT1 Scienze infermieristiche e ostetriche,
LM/SNT2 Scienze riabilitative delle professioni sanitarie,
LM/SNT3 Scienze delle professioni sanitarie tecniche,
LM/SNT4 Scienze delle professioni sanitarie della prevenzione
Dipartimento di Bioscienze - Via Celoria, 26 - Milano
- Main offices
Dipartimento di Bioscienze - Via Celoria, 26 - Milano - Degree course coordinator: prof. Ricagno Stefano
[email protected] - Degree course website
https://bioscienzebio.unimi.it/phd_stud
| Title | Professor(s) |
|---|---|
| Multilevel integration of water deficit signals in the floral network
Requirements: Molecular biology, genetics |
|
| Role of flavonoids in the prevention of inflammation and related molecular mechanisms
Requirements: Molecular biology, genetics |
|
| Unveiling the genetic and epigenetic mechanisms related to environmental changes
Requirements: Molecular biology, genetics and epigenetics |
|
| Investigation of alternative splicing dysregulation in tumors.
Requirements: Basic knowledge of genetics, molecular biology and bioinformarics |
|
| Defining novel molecular and cellular mechanisms that promote angiogenesis in neovascular diseases
Requirements: Basic knowledge of biochemistry, cellular and molecular biology and physiology |
|
| Sviluppo di diversi approcci per modulare Nfix in Cancro e nelle Distrofie Muscolari
Requirements: Molecular and celluylar biology, mouse model handling and histo-morphological analysis |
|
| Molecular modelling of biomolecular self-assembly processes
Requirements: Computational structural biology, statistical mechanics |
|
| Ion channel engineering for sonogenetics
Requirements: Cell electrophysiology, molecuar biology, biophysics of ion channels |
A. Moroni
|
| The relationship between flowering and stem elongation in rice
Requirements: basic knowledge of botany, genetics and molecular biology |
|
| Functional analysis of dependency-associated non-coding RNAs to discover novel vulnerabilities of human cancer
Requirements: Basic knowledge in genetics, epigenetics, molecular and cell biology |
|
| Study of the role of calcium signaling in plants under water stress using a reverse genetics approach based on the generation of multiple knock-out mutants of genes belonging to gene families encoding for calcium transporters
Requirements: Cellular and molecular biology, transport physiology |
|
| Development and implementation of cloud-oriented bioinformatic methods, tools and workflows.
Requirements: Molecular biology, bioinformatics, basic programming |
|
| Genetic biodiversity study in crops to improve seed quality
Requirements: Biologia cellulare, biologia molecolare, biologia dello sviluppo delle piante, scienze vegetali |
|
| Antibiotic persistence and the heterogeneity of replication and metabolic activities in bacterial populations
Requirements: bioinformatics skills, programming, small experimental involvement (flow cytometry) |
|
| A Drosophila model of Type B Kufs/CLN13 disease to study pathogenesis and Cathepsin F function
Requirements: basic knowledge of cellular and molecular biology, genetics, developmental biology |
|
| Structural and functional characterization of the chimeric protein RecTo4 for multiple sclerosis gene therapy
Requirements: Structural biology, biochemistry, molecular biology |
M. Milani (CNR)
|
| Structural and biophysical characterization of the amyloidogenic proteins responsible for systemic amyloidoses
Requirements: Basic understanding of structural biology and protein biophysics. |
|
| Development and application of bioinformatics methods for the integration of single-cell multi-omics data
Requirements: Basic knowledge in molecular biology and genetics. Knowledge of the basic concepts of computer programming. |
|
| Flourish or perish: pro-regenerative epigenetic programme to sustain axonal sprouting of peripheral nerves. Scholarship fully financed by Istituto Carlo Besta
Requirements: Basic knowledge of cellular and molecular biology |
|
| Looking at the role of microtubule dysfunction and stress-related pathways in pathological alpha-synuclein aggregation
Requirements: Basic knowledge of cellular and molecular biology |
|
| Investigation of the molecular mechanisms underlying the maintenance and degradation of the chloroplast in Arabidopsis thaliana and barley
Requirements: Basic knowledge of molecular biology and plant genetics |
|
| Investigation on early diagnostic procedure to detect neurodegenerative process
Requirements: Cell and Molecular Biology Dynamic Microscopy |
|
| Studying he methylase SMYD3 role in chromosome instability, in breast cancer.
Requirements: Epigenetics, genetics, cell and molecular biology |
|
| Studies of molecular genetic mechanisms that control the reproductive systems of plants to increase their productivity
Requirements: genetics, developmental biology, molecular biology |
|
| Molecular Control of inflorescence development in rice
Requirements: genetics, developmental biology, molecular biology |
|
| Molecular basis of DNA-binding and functional cooperativity of human Transcription Factors
Requirements: Human molecular genetics |
|
| Structural biology on transcription factors and on their interaction with DNA
Requirements: Molecular biology, biochemistry |
|
| Molecular basis of cardiac arrhythmias
Requirements: Physiology,cell biology |
|
| Novel factors regulating genome staility at non-canonical chromsomal structures in normal and cancer cells
Requirements: basic knowledge of genetics, molecular biology, bioinformatics |
|
| Cellular and molecular effects of cigar smoke on human alveolar type II cells and lung surfactant production
Requirements: Basic knowledge of human cell biology, biochemical methodologies, morphological analysis |
|
| Adattamento dello sviluppo dei meristemi riproduttivi in risposta ai cambiamenti climatici in Arabidopsis thaliana e Oryza sativa per il miglioramento della resa
Requirements: Knowledge of plant developmental biology, molecular biology and genetics. |
|
| A stem cell platform for studying somatic CAG instability in Huntington’s disease by single-cell DNA sequencing and transcriptional profiling of brain organoids and brains from treated animals
Requirements: Molecular biology, sequencing, human pluripotent stem cell technologies, some knowledge of bioinformatics |
|
| Searching for the best allelic variants responsible for the pale green leaf phenotype in barley
Requirements: Basic knowledge of molecular biology and biochemistry |
|
| Translational control in tumor organoids
Requirements: Omic studies on single cells. Establishment of human organoids |
|
| Unveiling the role of chlorogenic acid on anthocyanin bioactivity: a multi-species case study (ex DM 630/24)
Requirements: Molecular biology, genetics |
CREA
|
| Novel roles for CXCR4 signaling in hematovascular development (ex DM 630/24)
Requirements: Basic knowledge of biochemistry, cellular and molecular biology and physiology |
(HMGBiotech s.r.l)
|
| Antiviral-drug discovery and design: Design chemical modifications and prodrugs, by means of computational, structural and functional studies, to increase pharmacokinetic properties, bioavailability and cell permeability, and to reduce toxicity of molecules active on specific targets (e.g. antivirals, such as PBZ virucidal compounds recently identified against flaviviruses and coronaviruses) (ex DM 630/24)
Requirements: Basic knowledge of molecular biology and biochemistry |
E. Mastrangelo (CNR)
Linari Engineeering s.r.l
|
| Identification of 8 aa cyclic and linear peptides to be used as sustanable alternative to conventional pesticides in agriculture (ex DM 630/24)
Requirements: Basic knowledge of moleclar biology and biochemistry |
GOWAN CROP PROTECTION
|
Courses list
December 2024
| Courses or activities | Professor(s) | ECTS | Total hours | Language |
|---|---|---|---|---|
| Optional | ||||
| Membrane Protein Structural Biology: History, Methods, and Some Results | 2 | 12 | English | |
January 2025
| Courses or activities | Professor(s) | ECTS | Total hours | Language |
|---|---|---|---|---|
| Compulsory | ||||
| Biostatistics for Molecular and Cellular Biology | 5 | 27 | English | |
| Optional | ||||
| A World of Biological Images: from the Nanoscale to Micro and Mesoscale. a Guide to Electron and Optical Microscopy | 2 | 12 | English | |
February 2025
| Courses or activities | Professor(s) | ECTS | Total hours | Language |
|---|---|---|---|---|
| Compulsory | ||||
| Molecular and Cellular Biology. Methods and Communication of Results | 4 | 24 | English | |
| Optional | ||||
| Protein Structure Prediction and Design: How to Use Alphafold and Other Ai Methods for Research | 2 | 12 | English | |
March 2025
| Courses or activities | Professor(s) | ECTS | Total hours | Language |
|---|---|---|---|---|
| Optional | ||||
| Crispr/cas9: Practical Applications in Biotechnology | 2 | 12 | English | |
Enrolment
Places available: 16
Call for applications
Please refer to the call for admission test dates and contents, and how to register.
Application for admission: from 29/05/2024 to 27/06/2024
Application for matriculation: from 09/08/2024 to 31/10/2024
Attachments and documents
Qualifications assessment criteria
Following the programme of study
Contacts
Office and services for PhD students and companies