Clinical Research | Università degli Studi di Milano Statale

Doctoral programme (PhD)

A.Y. 2024/2025

Study area

Medicine and Healthcare

Doctoral programme (PhD)

Years

Dipartimento di Scienze Biomediche, Chirurgiche ed Odontoiatriche, Via della Commenda, 10 - 20122 Milano

English

PhD Coordinator

Del Fabbro Massimo

Course objectives

Students will learn a correct research approach for studying the causes and the clinical-therapeutic management of diseases.
Specific objectives:
? identify clinical issues and uncertainties in pathogenesis, diagnosis, prognosis and in therapeutic approaches in various diseases;
? correctly apply different research methodologies (randomized trials, longitudinal, cross-sectional or transversal studies and case control studies);
? identify and use biological and genetic markers for studying clinical syndromes, guiding diagnosis and assessing the clinical outcome of different pathologies;
? develop critical skills to analyse and comment clinical research results published or presented at national and international conferences;
? introduce students to independent clinical research methods and to the issues and critical points relating to ethics in clinical research.
The programme is entirely in English.

Entry requirements

Classi di laurea magistrale - Classes of master's degree:

LM-41 Medicina e chirurgia
LM-46 Odontoiatria e protesi dentaria
LM/SNT1 Scienze infermieristiche e ostetriche
LM/SNT2 Scienze riabilitative delle professioni sanitarie
LM/SNT3 Scienze delle professioni sanitarie tecniche
LM/SNT4 Scienze delle professioni sanitarie della prevenzione

Course location

Dipartimento di Scienze Biomediche, Chirurgiche ed Odontoiatriche, Via della Commenda, 10 - 20122 Milano

Contacts

Main offices
Dipartimento di Scienze Biomediche, Chirurgiche ed Odontoiatriche, Via della Commenda, 10 - 20122 Milano
PhD coordinator: Massimo Del Fabbro
[email protected]
Website
https://disbioc.unimi.it/

Research lines

Title	Professor(s)
1. Intra-operative protection of the saphenous vein used as a graft in cardiac and vascular surgery to allow for greater patency at a distance. 2. Study of the interaction between mechanical and paracrine factors in the progression of saphenous vein bypass disease. 3. Aortic valve insufficiency in relation to left ventricular size: what is the correct surgical timing? 4. Transcatheter aortic implantation (TAVR) in aortic valve disease: a study of access routes 5. Transcatheter aortic implantation (TAVR) in reoperations on degenerated aortic and mitral prostheses using the Valve-in-Valve technique (ViV TAVR) Curriculum: specialized medical sciences	Agrifoglio Marco
Prevalence of Chagas disease among people from Latin America living in Milano.2 Prevalence of Trypanosoma cruzi infection among Latin American pregnant women and incidence of vertical transmission.3 Epidemiology and clinical aspects of SARS-CoV-2 infection during different waves.4 Invasive pulmonary aspergillosis among patients affected by Covid-19critical disease.5 Chronic pulmonary aspergillosis 6 Leishmaniosis Curriculum: specialized medical sciences	Antinori Spinello
1. Pathophysiology, therapy and complications of hypothalamic-pituitary diseases . 2. Thyroid and adrenal cancers: Studies on clinical aspect, prognostic risk factors, new biomarkers and innovative treatments . 3. New approaches for the diagnosis and prognosis of rare endocrine diseases 4. Pathophysiology, diagnosis and therapy of thyroid autoimmune diseases and Graves' ophthalmopathy Curriculum: specialized medical sciences	Muller Ilaria
Morphological and functional adaptation of right ventricle ad different stages of pulmonary circulation involvement in heart failure patients with reduced ejection fraction Curriculum: specialized medical sciences	Bandera Francesco
1. Videolaparoscopic surgical treatment of symptoms associated with pathological gastroesophageal reflux through the use of devices: cardiac magnetic sphincter (MSA) and refluxstop (RS). Intraoperative pathophysiological evaluation of the esophageal distensibility index using endoflip. Curriculum: specialized medical sciences	Bona Davide
1. Prehabilitation in upper digestive surgery; 2. Endoscopic screening of gastroesophageal reflux disease and Barrett’s esophagus with brush citology; 3. Hemodynamic effects after repair of large hiatal hernia; Curriculum: specialized medical sciences	Bonavina Luigi
1. Diseases of the pericardium. 2. Pregnancy in autoimmune diseases. 3. VASCULITIS: pathogenesis, diagnosis, therapy, folow-up. 4. FRAGILE MULTIMORDIB PATIENTS. Curriculum: specialized medical sciences	Brucato Antonio Luca
1. Innovative approaches to early diagnosis of Autism Spectrum Disorders 2. Multidisciplinary characterization of epilepsy and/or neurodevelopmental disorders 3. Central Nervous System involvement in Sars-Cov-2 Infection Curriculum: specialized medical sciences	Canevini Maria Paola
Radiomics and "multi-omics" in diagnostic and interventional radiology: 1. evaluation of radiomic features for the choice of optimal treatments, with particular attention to oncological and vascular disease (malformations of head-neck district); 2. integration of radiomic data with different sets of features (genomic, metabolomic, proteomic) for better selection and definition of patients eligible for different therapies (responders/ non responders) Curriculum: specialized medical sciences	Carrafiello Gianpaolo
1. Use of respiratory function tests for diagnosis and follow-up of patients with Covid-19. 2. Differential effects of hypoglycemic therapies on survival in diabetic patients with COVID 19. 3. Evaluation of acute respiratory failure in patients with type 1 respiratory failure including Covid 19 patients. Curriculum: specialized medical sciences	Di Marco Fabiano
Endocrine disorders in patients with common diseases (diabetes mellitus and/or hypertension and/or osteoporosis) Curriculum: specialized medical sciences	Chiodini Iacopo
1. Bariatric-metabolic surgery as a model for studying nutritional ketosis Curriculum: specialized medical sciences	C. CONTE
1. Clinical methodology (critical evaluation of choosing in medicine and scientific literature). 2. Risk stratification in cardiovascular diseases and in emergency situations, expecially in syncope. Curriculum: specialized medical sciences	Costantino Giorgio Massimiliano
Study of microcirculation:pathophysiologic and clinical implications. Curriculum: specialized medical sciences	Cugno Massimo
1) Modulation of the metabolism of the malignancies through the use of metformina and fast mimicking diet Curriculum: specialized medical sciences	De Braud Filippo Guglielmo Maria
1) "Nasal Function" - CFD 2) "Sleep disorders in ENT" 3) Olfactory impairment in SARS-Cov-2 infection 4) Audiology and vestibology 5) Personalized medicine in chronic rhinosinusitis Curriculum: specialized medical sciences	Felisati Giovanni Pipolo Giorgia Carlotta
Clinical Aspects,imaging, genetics and bimolecular aspects of nurodegenerative diseases of the central nervous system. In particular: 1) Role of the glymphatic system in neurodegenerative diseases: multimodal characterization through neuro-imaging and plasma/serum biological markers 2) From neuroinflammation to neurodegeneration: expression of inflammatory proteins in biological fluids and extracellular vesicles 3) miRNA and lncRNA expression in biological fluid and exosomes.4)Role of atypical lymphocytes in aberrant microglia activation during neuroinflammatory and neurodegenerative processes, with particular attention to CD3+CD20+ cells Curriculum: specialized medical sciences	Galimberti Daniela
1. Physiopathological mechanisms of insulin-resistance in obesity and diabetes. 2. Implications for atherosclerosis acceleration and microvascular complications. 3. Differential effects of hypoglycemic therapies on survival in diabetic patients with COVID 19 Curriculum: specialized medical sciences	Folli Franco
1. Hepatic steatosis and its cardiovascular complications as co-morbidities in different clinical settings (diabetes, viral infection, includings, IBD, liver transplantation). 2. Bidirectional relationship between hepatic steatosis and altered body composition (obesity, sarcopenia and sarcopenic obesity). 3. Role of gut and saliva microbiota and sarcopenia in determining liver and cardiovascular damage in diabetic patients with Non-Alcoholic Fatty Liver Disease. 4. Dynamic scores (including clinical, anthropometric, and genetic data, with application of artificial intelligence) for risk stratification of severe liver and cardiovascular disease Curriculum: specialized medical sciences	Fracanzani Anna Ludovica
Clinical characterization, biomarkers, and innovative treatment of adults with severe mental disorders Curriculum: specialized medical sciences	D'Agostino Armando
Clinico-pathological characterization of the effects of specific therapies on the bone marrow, for the treatment of patients with MielodisplaticMieloproliferative syndromes. Curriculum: specialized medical sciences	Gianelli Umberto
1. Custom-made maxillary and mandibular reconstructions prior to implant surgery and maxillofacial oncologic surgery. 2. Sars-CoV-2 and other viral infections in HNSCC: genetic and epigenetic susceptibility characterization and related patient clinical profiles 3. Customized three-dimensional synthesis means in orthognathic surgery and in OSAS maxillofacial surgery; evaluation of splintless planning accuracy Curriculum: specialized medical sciences	Gianni' Aldo Bruno
Use of ex vivo confocal microscopy in the diagnosis of oncological pathologies in urology Curriculum: specialized medical sciences	Rocco Bernardo Maria Cesare
Role of the autologous adipose tissue in tissue regeneration, in fibrosis reduction and in scar-pain control. Curriculum: specialized medical sciences	Klinger Marco Ettore Attilio
"Retinal and choroidal disorders" Curriculum: specialized medical sciences	Invernizzi Alessandro
Immunotherapy in head and neck tumours. Curriculum: specialized medical sciences	Licitra Lisa Francesca Linda
1) Development of personalized therapies in tumors of the nervous system. 2) New knowledge and surgical therapies in movement disorders. Curriculum: specialized medical sciences	Locatelli Marco
1. Use of transcranic electromagnetic stimulation for the treatment of the endocrino-metabolic diseases. 2. Olfactory alterations and diabetes: early biomarker for disease complications 3. Metabolic effects of obstructive sleep apnea syndrome Curriculum: specialized medical sciences	Luzi Livio Mozzanica Francesco
1) cardiologic and pneumologic implications of OSAS. 2) development of new diagnostic tools for the siagnosis of OSAS Curriculum: specialized medical sciences	Mozzanica Francesco
1) Cutaneous manifestations associated with COVID-19 vaccines and new disease variants : clinical, histopathological and immunological study based on an Italian registry 2) Comparison between classical and syndromic HS: a genetic and immunological study Curriculum: specialized medical sciences	A. V. Marzano
1) Clinical and immunohistochemical characterization of immune-mediated alopecias: from the pathophysiological scenario to possible treatment targets Curriculum: specialized medical sciences	A. V. Marzano
1. Urothelial cancer: new diagnostic and therapeutic approaches 2. Translational analysis of the impact of HLA-G-related tolerance in overall health in infertile vs. fertile men. 3. Rare urological malignancies: penile and testicular cancer. Risk factors and predictors of lymph nodal and advanced disease analysis to develop personalized treatments. Curriculum: specialized medical sciences	Montanari Emanuele
Assesment and modulation of autonomic nervous system in acute and chronic diseases Curriculum: specialized medical sciences	Montano Nicola
1) Pathophysiology, clinics and personalized therapeutic strategies in myelodisplastic/myeloproliferative neoplasms. 2) Cutaneous T-cell lymphomas in advenced stages: study on the biological-molecular factors and on the main clinical variables in predicting the response to the diverse therapeutcal strategies Curriculum: specialized medical sciences	Onida Francesco
1. Recurrent infective-inflammatory disease of the upper airways. 2. Mini-invasive surgery for airways obstructions. 3. Clinical expressions and relapse in ENT of the COVID-19 pandemic. 4. Biologic treatments for chronic rhinosinusitis with nasal polyps. 5. The role of nasal microbiota in pediatric upper airway infections Curriculum: specialized medical sciences	Pignataro Lorenzo Torretta Sara Silvia Gaffuri Michele
1. Assessment of structure/funcion relationship in glaucomatous damage 2. Efficacy of neuropritection in slowing glaucoma progressio 3. Evaluation of the role of inflammation in retinitis pigmentosa: therapeutic implications 4. Evaluation of the ocular surface in the elderly: comparison of different molecules in restoring lacrimal film Curriculum: specialized medical sciences	Rossetti Luca Mario
1. HIV infection: clinical, metabolic and pharmacological correlates and focus on genotypic and phenotypic resistance. 2. In vitro pharmacological response of SARS-CoV-2 to different drug classes with a different mechanism of action Curriculum: specialized medical sciences	Rusconi Stefano
1. Setup of a national database for the functional, respiratoty and clinical characterization in a wide population of patients suffering from cronic obstructive broncho-pulmonary disease. 2. Burden and clinical outcomes of respiratory viral infections 3. The role of lung ultrasound in assesing idiopathic pulmonary fibrosis progression and its correlaion with lung function. Curriculum: specialized medical sciences	Santus Pierachille
Novel biomarkers of cardiovascular risk associated with adipose tissue plasticity in obese and / or diabetic subjects Curriculum: specialized medical sciences	Terruzzi Ileana Marina
Autonomic nervous system from bench to bedside: physiopathological and clinical aspects and new therapeutic approaches using vagal stimulation. Curriculum: specialized medical sciences	Tobaldini Eleonora
1. Evaluation of the role of radiant therapy in the treatment of intractable ventricular tachycards co. 2. Role of transcathere ablation of the back wall of the left atrium for the treatment of persistent atrial fibrillation 3. Role of hybrid therapy (surgical+electrophysiological) in the treatment of chronic forms of atrial fibrillation 4. Effectiveness of mechanical closure of the left auricola compared with conventional anticoagulant therapy in thromboembolic prevention in patients with atrial fibrillation 5. Effectiveness and safety of new leadless pacemakers with accelerometer sensor for AV synchronization in patients with intermittent AV block 6. Effectiveness and safety of left branch stimulation in patients with a need for heart stimulation 7. Role of endomyocardial biopsy in arrhythmic risk stratification in cardiomyopathy patients 8. Efficacia e sicurezza della modulazione della contrattilità miocardica nei pazienti con scompenso cardiaco. Curriculum: specialized medical sciences	Tondo Claudio
New pathophysiological knowledge for the design of endovascular treatment of thoracic and abdominal aorta diseases. Curriculum: specialized medical sciences	Trimarchi Santi
Analysis of cardiovascular stiffening after thoracic and abdominal aortic diseases management using endovascular treatment Curriculum: specialized medical sciences	Trimarchi Santi
1. Safety and efficacy of the Thulium laser system for endoscopic therapy of gastrointestinal lesions: a multicenter study. 2. Novel biomarkers for complicated and non-responsive celiac disease. 3. Nutritional status as a prognostic index in patients with Inflammatory Bowel Disease or Short Bowel Syndrome: evaluation of therapeutic strategies. Curriculum: specialized medical sciences	Vecchi Maurizio
1. Ocular surface pathophysiology, clinics and therapeutic strategies 2. The eye as a window on the immune system Curriculum: specialized medical sciences	Villani Edoardo
Development and validation of a four-dimensional modeling software of the musculoskeletal system with focus on the lower limb, aimed at replicating with good reliability the kinematics and dynamics of the body segment. Design and implementation of innovative tools for the preoperative planning of hip and knee replacement, in order to optimize the identification of alignment targets for the prosthetic components. Curriculum: specialized medical sciences	Sansone Valerio Cesidio
Diagnostic, interventional and quantitative radiology, with particular reference to musculoskeletal system and applications of artificial intelligence to imaging. Curriculum: specialized medical sciences	Sconfienza Luca Maria
1 - Study of the progression of reticular drusen.2 - Research and validation of retinal biomarkers for the monitoring and diagnosis of systemic diseases 3 - Advances in imaging for the diagnosis and monitoring of age-related macular degeneration Curriculum: specialized medical sciences	Viola Francesco
“The complications in clinical trial: management and medical liability" Curriculum: specialized medical sciences	Zoia Riccardo
1. New methodological and technological developments in physical and rehabilitation medicine 2. Verification of efficacy of therapies and reliability of outcome measurements in vertebral deformities Curriculum: specialized medical sciences	Negrini Stefano
1. Research of new biomarkers of systemic cutaneous disorders by integrating multi-omics with artificial intelligence. 2. Defintiion of the main endotype to apply one-helath and precison medicine concepts. Curriculum: specialized medical sciences	Damiani Giovanni Del Fabbro Massimo Muti Paola Cornelia Maria
1- Study of the predictors of functional recovery in patients suffering from respiratory pathologies, through the investigation of diaphragmatic and peripheral muscles function 2- Study of predictive models of post-lung transplantation outcomes validated through clinical and instrumental follow-up 3- Identification of the intraoperative phase during lung transplantation of onset of the phrenic nerve conduction defect and therefore of post-transplantation diaphragmatic dysfunction 4- Identification of patients at risk by dedicating a personalized approach to the prevention and treatment of diaphragmatic dysfunctions 5- Study the impact of the transplant on the shape of the diaphragm and the functional consequences of the mismatch on the size of the donor/recipient lung 6- Identify clinically measurable predictors of diaphragmatic dysfunction assessed by ultrasound, histology and molecular biology Curriculum: specialized medical sciences	Palleschi Alessandro
Drug interactions: clinical pharmacology study approaches and new approaches with artificial intelligence. Curriculum: specialized medical sciences	Pani Arianna
Neural control of ventilation: breathing pattern, pulmonary-volume feedback and respiratory muscles electromiography Curriculum: specialized medical sciences	Grasselli Giacomo
1.Optimizinig the management of patients with acute respiratory failure (i.e., mechanical ventilation, extracorporeal membrane oxygenation), with particular focus on the clinical and biological phenotyping of patients' cohorts Curriculum: specialized medical sciences	Grasselli Giacomo
1. Assessment and optimization of the critical care management of patients ungergoing solid organ transplant Curriculum: specialized medical sciences	Scaravilli Vittorio
1) Advancing ICU Care: Development of AI and Machine Learning Algorithms for Clinical Decision Support Curriculum: specialized medical sciences	Scaravilli Vittorio
1. mucosal immunity and development of organoids in HIV infection; 2. Immunopathogenesisi of COVID-19 and Long COVID; 3. real-life studies on novel anitibiotics for MDR germs and implementation of antimicrobial stewardship strategies Curriculum: specialized medical sciences	Marchetti Giulia Carla
1. Non-invasive study of coronary atherosclerosis through cardiac CT; 2. Physiopathology of cardiomyopathies through genetic assessment and advanced imaging; 3. Clinical studies on pericardial syndromes (acute pericarditis, chronic pericarditis, and pericardial effusion); 4. Diagnostic and prognostic evaluation in the field of sports cardiology. Curriculum: specialized medical sciences	E. Conte
1 Immunology and virology of HIV-1 infection 2 Epidemiology, virology and immunology of SARS-COV-2 infection 3. Pathogenesis of Long Covid focusing on NeuroCOVID 4 Safety and efficacy of vaccines in immunocompromised subjects 5 Clinical trials on antiretroviral drugs and new vaccines Curriculum: specialized medical sciences	A. RivaI
Role of inlammaging in the pathogenesys of acute a chronic damage in nephropaties and transplantation Curriculum: specialized medical sciences	Castellano Giuseppe
Development and validation of a therapeutic algorithm for the management of patients diagnosed with hepatocellular carcinoma, on the basis of the BCLC staging system and therapeutic hierarchy: multiparametric model. Curriculum: specialized medical sciences	Lampertico Pietro
Optimization of the management of patients suffering from HBV-related chronic hepatitis with/without HDV coinfection: from early diagnosis to optimization of treatment, surveillance and management of medium/long-term complications (clinically significant portal hypertension, hepatocellular carcinoma, liver failure) Curriculum: specialized medical sciences	Lampertico Pietro
1) Analysis of the relationship between geriatric syndromes (multimorbidity, sarcopenia, polypharmacy, frailty) and cardiovascular diseases, in determining clinical management, the risk of major adverse clinical events and the impact on quality of life and the use of healthcare resources Curriculum: specialized medical sciences	Proietti Marco
1. Evaluation of homologous nerve grafts in the reconstruction of the nerves of the oral cavity. 2. Study of the effectiveness of facial nerve neurorrhaphy in the term-terminal and termino-lateral modalities. Curriculum: Oral Sciences	Biglioli Federico
1. Epidemiology of oral diseases especially dental caries 2. Caries prevention agents and their use in populations at high risk of disease 3. Children with Special needs and oral health: preventive and therapeutic strategies 4. Maternal and children's oral health promotion and prevention Curriculum: Oral Sciences	Cagetti Maria Grazia
Radioprotection in medicine concerning diagnosis treatment and therapy. Risks and benefits evaluation regarding patient characteristics. Curriculum: Oral Sciences	M. C. CANTONE
1) Comparative mapping of viroma and microbiome of the upper respiratory tract in SARS-CoV-2 patients; 2) Development of an integrated proteomic and metabolomic approach for the treatment of SARS-CoV-2 patients admitted to intensive and subintensive therapies. Curriculum: Oral Sciences	Capaccio Pasquale
1. Clinical and lab validations of new orthodontic devices Curriculum: Oral Sciences	Caprioglio Alberto
Systematic reviews, meta-analysis and network meta-analysis to synthesize the evidence in dentistry Curriculum: Oral Sciences	Del Fabbro Massimo
Autologous dentin matrix and platelet concentrates for alveolar site preservation and bone defects reconstruction procedures in oral surgery Curriculum: Oral Sciences	Del Fabbro Massimo Taschieri Silvio Luigi Maria
1. Morphofunctional analyses of organs and tissues of the oral system. 2. Evaluation of the sustainability, efficiency and effectiveness of oral health promotion programs aimed at including oral care in primary care. Curriculum: Oral Sciences	Dellavia Claudia Paola Bruna
1. Modern therapeutic approaches for periodontal and peri-implant diseases. 2. Study of the correlation between periodontal diseases and systemic conditions Curriculum: Oral Sciences	Francetti Luca Angelo Corbella Stefano
1. Interaction of the microbial flora of the oral cavity with modern materials used in Restorative and Prosthetic Dentistry. The line includes the study and synthesis of dental materials with antibacterial and bioactive properties also using nanotechnologies with a bottom-up approach, the study of their surface characteristics, mechanical tests on materials, the development and use of flow bioreactors, the use of optical, SEM, confocal microscopes to the CLSM laser. 2. Development of in vitro models for simulating the microbiological aging of materials for dental use. 3. Development of in vitro microbiological models for the study of demineralization / remineralization of dental hard tissues, also using micro-CT. Development and study of active principles with remineralizing activity. 4. Development of 3D tissue models of reconstituted human epithelium for the evaluation of the efficacy of active ingredients and models of microbial co-infections. 5. Development of flow bioreactor models for the study and prevention of microbial infections of catheters. 6. Development of a protected environment for the evaluation of the spread via aerosol of infections in the clinical setting, in particular for the evaluation of measures to protect the Operators and limit the spread of Coronavirus in the Dental field. Curriculum: Oral Sciences	Ionescu Andrei Cristian E. BRAMBILLA
Etiopathogenesis, diagnosis, treatment and prognosis of mucosal lesions with particular attention towards potentially malignant ones. Curriculum: Oral Sciences	Lodi Giovanni Lorenzo
1. ONE-PIECE MONOPHASIC IMPLANTS: Prospective observational cohort study. Radiographic evaluation of MBL at one-piece monophasic implants inserted in full-arch rehabilitations with full-digital approach and immediate loading. 2. MATRICES FOR SOFT TISSUE GROWTH: RCT evaluation of the increase of soft tissue with pig collagen matrix placed in split and full thickness techniques with scans at 1-3-6-12 months. 3. INCREASE IN PERIMPLANTARY SOFT TISSUES: RCT evaluation of soft tissue increase with roll flap vs connective tissue grafting approach.Volumetric and PES 12-month assessment. 4. Evaluation of peri-implant bone level in implant placed following partial versus full thickness flap approaches: prospective randomized 3-year study. 5. Randomized, double-blind, active-controlled, placebo-controlled, parallel group, single dose, multicenter study to evaluate the analgesic effect of CR4056 in postoperative dental pain - ACTS 1262/2018. 6. Clinical evaluation of the effectiveness of a reabsorbable collagen membrane in guided bone regeneration for implant-prosthetic purposes - ACTS 1124/2017. 7. Study of the neuromuscular behavior of the elevating muscles of the jaw (temporal and masseter) and of the cranial postural muscles (sternocleidomastoid and trapezius) as possible indicators of an occluded-postural imbalance in subjects of the ballet dances between 16 and 24 years old. 8. Evaluation of the biocompatibility of prosthetic suprastructures made of BioHPP in impland dentistry: clinical and radiological pilot study. ACTS 447/2022 Curriculum: Oral Sciences	Maiorana Carlo Beretta Mario
1. Study of the individual resistance determinants and environmental protective factors in Sars-CoV-2 infections in populations with low prevalence of infection. 2. Study of the adaptive immune response to Sars-CoV-2 infections in exposed and non-exposed populations (immunological response through cross-reactivity) Curriculum: Oral Sciences	Muti Paola Cornelia Maria
1. Regeneration of Periodontal and peri-implant tissues, in particular surgical techniques, scaffolds and growth factors. 2. Development of 3D printed scaffolds for the regeneration of maxillary processes. 3. Identification of "treatable traits" and characterization of "personalized therapy" in asthmatic subjects. Curriculum: Oral Sciences	Rasperini Giulio
Single edentulism treatment through implant-supported rehabilitation with autologous connective or heterologous matrix graft. Multicentric, randomized controlled study. Curriculum: Oral Sciences	Romeo Eugenio
1. Impact of chronic facial pain disorders (Burning Mouth Syndrome, Persistent Idiopathic Facial Pain) on the oral, systemic and mental health conditions of patients and their family members. Curriculum: Oral Sciences	Sardella Andrea
Evaluation of molecules with anti-biofilm activity for the prevention and treatment of peri-implantitis. Curriculum: Oral Sciences	Sisto Francesca
Efficacy of laser biostimulation in pain and oedema reduction after impacted mandibular third molar extraction: multicentric, randomized study. Curriculum: Oral Sciences	Spadari Francesco
1. Wearables BioSensor Technologies for Oral Metabolic Agents in saliva 2. Semiautomatic and Automatic 3D craniofacial analysis through Artificial Intelligence (AI) methods and its application in orthodontics and maxillo-facial surgery 3. 3d on chair printed aligners. Validation of their clinical efficacy Curriculum: Oral Sciences	Tartaglia Gianluca Martino Tartaglia Gianluca Martino Tartaglia Gianluca Martino Caprioglio Alberto
1) Development of drug release systems for the prevention and treatment of diseases of the oral mucosa; 2) Analysis of oral microbiome in relation to oral mucosal diseases Curriculum: Oral Sciences	Varoni Elena Maria
Cardiac amyloidosis: early diagnosis in high risk subjects (ex DM 630/2024)	Bandera Francesco (IRCCS MultiMedica – MultiMedica S.p.A)
Sugar-free chewing gums and oral health: benefits and risks of their use (ex DM 630/2024) Requirements: Knowledge of surface electromyography Curriculum: Oral Sciences	Cagetti Maria Grazia (Perfetti Van Melle S.p.A.)