Molecular Biology of the Cell

Ragazza in laboratorio
Molecular Biology of the Cell
Course sheet
A.Y. 2025/2026
Master programme
LM-6 R - Biologia
Master programme
120
ECTS
Access
Open with entry requirements examination
2
Years
Language
English
The MBC course covers all principal areas of the LM-6 Biology course, with a unique focus on biomolecular subjects that distinguishes it from other courses of the same LM Class. The main goal of the MBC course is to train biologists in advanced biomolecular research, to address present and future scientific challenges.
In-depth and up-to-date knowledge will be provided for the following subjects: molecular analysis of the genome; regulation of gene expression; structure and function of biological macromolecules and their interactions in pramolecular complexes; cellular communication, signal perception and transduction, metabolic regulation, biomolecular engineering, bioinformatics, biostatistics and biotechnological applications in both pharmaceutical and agri-food sectors. Both theoretical and practical aspects of biomolecular research will be addressed. Graduate students will learn to apply novel and emerging research technologies/approaches, cutting-edge data acquisition systems and analysis, and will have hands-on experience with top-level nanotechnology, hosted in the research laboratories of the DBS. MBC graduates will be well-equipped to enter further, postgraduate-level education programmes as well as R&D departments of different biotech companies.
Biologist
Role in a work context:
The offering of the Master's Degree in Molecular Biology of the Cell entirely in English enables graduates to access both national and international job markets.
Graduates of the Master's Degree in Molecular Biology of the Cell perform high-responsibility roles in professional contexts that include:
? promotion and development of scientific methodologies;
? managerial roles in public or private institutions dedicated to environmental conservation and management, biological research laboratories, biotechnological, pharmaceutical, and food industries, as well as professional fields requiring a multidisciplinary approach to molecular biology-related issues;
? management of clinical trials;
? activities in scientific publishing and dissemination.

According to DPR 328/01, graduates are eligible to take the state exam to obtain the qualification for the profession of biologist and to enroll in the National Order of Biologists. To achieve higher levels of responsibility, graduates may also pursue PhDs, Specialization Schools, and second-level Master's programs, subject to passing the respective admission exams.

Skills associated with the role:
Graduates of the Master's Degree in Molecular Biology of the Cell possess advanced and modern knowledge in the fields of molecular biology and bioinformatics. Their strong theoretical foundation and in-depth understanding of analytical methodologies, data acquisition, and analysis techniques in molecular cell biology provide specific preparation for professional and project activities in areas related to biological disciplines in the healthcare, pharmaceutical, agri-food, environmental, and biotechnological industries.

Career opportunities:
? Universities and public or private research institutions;
? Public and private laboratories specialized in biological, microbiological, genetic analyses, and quality control;
? Pharmaceutical, chemical, biotechnological, and agri-food industries;
? Communication, dissemination, and scientific information sectors, including scientific publishing in the biomolecular field.

Molecular Biologist
Role in a work context:
Graduates of the Master's Degree in Molecular Biology of the Cell perform high-responsibility roles in all professional contexts involving advanced research in biological and applied sciences. They work in university laboratories, other public or private research centers, and industries, with a particular focus on biochemical, genetic, biophysical, molecular, bioinformatic, and biotechnological aspects.

According to DPR 328/01, graduates are eligible to take the state exam to qualify for the profession of biologist and, consequently, to register with the National Order of Biologists. They can also pursue PhDs, Specialization Schools, and second-level Master's programs, subject to passing the relevant admission exams.
Skills associated with the role:

Graduates of the Master's Degree in Molecular Biology of the Cell possess a specific and modern cultural preparation in molecular biology and bioinformatics. They are particularly equipped to conduct basic and applied research in the industrial, healthcare, and public and private sectors. Their work focuses on understanding the molecular bases of biological phenomena, developing biological and molecular analysis methodologies, and applying biological, genetic, and biochemical knowledge in healthcare, agri-food, and environmental fields.

Career opportunities:
? Universities and public or private research institutions;
? Public and private laboratories specialized in biological, microbiological, genetic analyses, and quality control;
? Pharmaceutical, chemical, biotechnological, and agri-food industries;
? Fields related to communication, dissemination, and scientific information, including scientific publishing in the biomolecular domain.

Researchers and Technicians with Degrees in Biological Sciences
Role in a work context:
Graduates of the Master's Degree in Molecular Biology of the Cell perform high-responsibility roles in all professional contexts requiring the development of research on concepts and theories related to molecular cell biology:
? collaborate with university professors, assisting them in the design and implementation of teaching and curricular activities;
? support students in their academic activities;
? design and conduct theoretical and experimental research in academia aimed at expanding and innovating scientific knowledge or its application in productive contexts;
? ensure the proper functioning of laboratories and scientific equipment;
? define and implement scientific protocols in laboratory experiments and research activities.

According to DPR 328/01, graduates are eligible to take the state exam to qualify for the profession of biologist and, consequently, to register with the National Order of Biologists. They can also pursue PhDs, Specialization Schools, and second-level Master's programs, subject to passing the relevant admission exams.

Skills associated with the role:
Graduates of the Master's Degree in Molecular Biology of the Cell possess a specific and modern cultural preparation in the fields of molecular biology and bioinformatics. Their solid academic background and in-depth knowledge of analytical methodologies, as well as data acquisition and analysis techniques in molecular cell biology, provide them with the expertise necessary for professional and project activities. These include managing and operating productive technologies, technological platforms, analytical methodologies, and scientific instruments in the healthcare, pharmaceutical, and agri-food sectors.

Career opportunities:
? Universities and Research Institutions;
? Public and private research laboratories.
MBC students are given the opportunity to spend part of their curriculum abroad, at a University within the European Union (EU), in the context of the Erasmus+ mobility for study program of the European Commission. Students can attend courses and sit exams that can be included in the core curriculum and/or perform their practical thesis in several European Universities localized in North Europe (Norway, Denmark, Netherlands), France, Germany, Ireland and Iberian Peninsula (visit the link: https://dbs.unimi.it/it/rapporti-internazionali/il-dipartimento-nel-mondo/accordi-internazionali). Most of the European Universities offer master courses taught in English. The Erasmus+ mobility for study call is released each year, usually in February. More information can be found at https:// www.unimi.it/en/international/study-abroad/studying-abroad-erasmus.
Thanks to the participation of the University of Milan in the 4EU+ Alliance, MBC students have the opportunity to earn academic credits (up to a maximum of 12) by attending courses virtually at partner universities (Sorbonne Université in Paris, Paris-Panthéon-Assas University, Charles University in Prague, University of Copenhagen, University of Geneva, Heidelberg University, and the University of Warsaw).
Students interested in conducting research abroad as part of their thesis can also take advantage of the Erasmus+ mobility for Traineeship program and the "Thesis Abroad" call.
Accepted students must present a study plan that reports all the activities he/she intends to perform abroad, detailing the corresponding CFUs; the number of proposed CFUs should approximately correspond to those the student would have
achieved over the same time period in his/her university. The proposed Erasmus+ program study plan, must be coherent with the MBC course content and must be evaluated and approved by the Academic Board. If necessary, the Academic
Board may request the student to integrate the program of exams taken abroad. In accordance with the rules established by the Academic Senate, following completion of the Erasmus+ program, approved exams will be registered, possibly with
the original denomination, as part of the student's curriculum, upon the conversion of the European Credit Transfer and Accumulation System (ECTS) into CFUs.
If the student performs the experimental thesis work abroad, he/she must follow the rules outlined above (see Internship criteria and Rules for the thesis and final exam).
The Erasmus and international mobility advisors for Biological area are prof. M. Cristina Bonza ([email protected]) and prof. Federica Marini ([email protected]).
Course attendance is strongly recommended.
Enrolment
QUALIFICATIONS AND KNOWLEDGE REQUIRED FOR ADMISSION
The admission to the MBC course is subjected to curricular requirements and a demonstrated background knowledge in suitable disciplines related to the course (DM 270/04). Admission is open to:
- Graduates in Biological Sciences (Class L-13) from any Italian University that follows CBUI rules, as adequately certified. In this case, credits (ECTS) acquired by the candidate as an undergraduate will be fully recognized and will meet the curricular prerequisites. The CBUI guidelines describe the compulsory SSD (scientific areas) and the related recommended number of ECTS (min-max):
- 66-96 CFU in basic biological disciplines, including 18-27 ECTS in the fields of botany, plant physiology, zoology, comparative anatomy, or ecology (BIO/01, BIO/02, BIO/04, BIO/05, BIO/06, BIO/07); 18-24 ECTS in physiology or biochemistry (BIO/09, BIO/10); 30-45 ECTS in molecular biology, genetics, and microbiology (BIO/11, BIO/18, BIO/19);
- 12-15 ECTS in non-biological basic chemical disciplines (CHIM/01, CHIM/02, CHIM/03, CHIM/06);
- 15-18 ECTS in non-biological basic disciplines such as mathematics, physics, and computer science (MAT/01-09, FIS/01-08, and INF/01).

The following candidates may also be admitted:
- Graduates from the same L-13 degree class who have not followed an academic path aligned with the CBUI guidelines, or from the L-12 degree class in Biological Sciences under DM 509/99, or from other degree classes, as well as those who have obtained a foreign qualification recognized as suitable under current regulations, provided they meet the required curricular prerequisites. Specifically, the curricular prerequisites consist of holding an adequate number of ECTS, usually no less than 90 CFU, distributed across SSDs of non-biological disciplines (CHIM/01-03, CHIM/06, MAT/01-09, FIS/01-08, and INF/01) as well as SSDs of basic and core biological disciplines (BIO/01-02, BIO/04-07, BIO/09-11, BIO/18-19), as described above;
- Graduates from the L-2 degree class (Biotechnology) who have obtained at least 57 CFU in basic biological disciplines (BIO/01-02, BIO/04-07, BIO/09-11, BIO/18-19).
Students lacking adequate curricular requirements should contact the Coordinator of the Master's course well in advance, to plan the acquisition of the requested ECTS prior to the application deadline. Any lacking ECTS can be acquired by passing the relevant exams and thus acquiring the credits at the University of Milan or any other University. Only students who possess the prerequisites will be invited to the interview.

ADMISSION ASSESSMENT
The admission exam will consist of a formal interview (that can be arranged online) with an Evaluation Committee that will verify the candidate's background knowledge in Molecular biology, Genetics, Microbiology, Biochemistry and Physiology. A Syllabus will be made available to students prior to their interview for a self-assessment of their level of knowledge.
For all students, knowledge of the English language must be at least B2 level ("Upper-intermediate") according to the Common European Framework of Reference (CEFR) for Languages or equivalent certification. The proficiency in scientific English will be verified by the committee during the interview.

KNOWLEDGE ASSESSMENT
The prerequisite to enter the MBC Master's Degree program is an adequate knowledge of the fundaments of biological disciplines as certified by the possession of the required ECTS as described in paragraph "Qualifications and knowledge required for admission". Knowledge will be verified by: 1) evaluation of the bachelor study program and 2) an interview with the Admission Committee, composed of teaching members appointed by the Academic Board. The interview will evaluate the expertise of the candidate in topics related to the MBC degree, and will ascertain proficiency in the English language.
The committee will evaluate the candidate on a 100-point scale and award:
- 25/100 points for the graduation grade, or, in the case of graduating students, the average grade of the exams taken;
- 10/100 points for the curriculum studiorum (degrees with higher number of ECTS in biology related disciplines will obtainmore points; the same applies to the presence of extra elective courses, Erasmus experience, others,...)
- 65/100 for interview performance
The minimum requirement for admission is 60/100 and an adequate English proficiency level (equivalent to B2 level).
For the academic Year 2025--2026, applicant interviews for EU citizens, who submit their application by 25 August 2025 (see below, "Application and enrolment information and procedures"), will be held face-to-face on September 08, 2025 at 14.30, for both graduate students and undergraduate students that plan to graduate by December 31, 2025; Students must bring official proof of their identity (identity card or passport).
Upon graduation, students not from University of Milan, must present certification of their awarded degree to the Administrative Office or email via https://informastudenti.unimi.it

Non-EU citizens applying for a visa, who are not resident in Italy and who possess a foreign bachelor's degree title, must submit their application by 30 April 2025 and they will be invited to an online interview in the following days:
- February 28, 2025
- March 21, 2025
- April 08, 2025
- April 22, 2025
- May 06, 2025
- May 27, 2025
Foreign students who reside in Italy are classed as Italian citizens and must undergo the same evaluation. Check for updates on interview dates and times on the website: https://mbc.cdl.unimi.it

Admission

Application for admission: from 22/01/2025 to 25/08/2025

Application for matriculation: from 02/04/2025 to 15/01/2026


Attachments and documents

Admission notice

Learn more:
Programme description and courses list
First semester
Courses or activities ECTS Total hours Language SSD
Compulsory
Advanced Molecular Biology 6 48 English BIO/11
Molecular Bioinformatics 6 48 English BIO/11
Organic Chemistry Applied to Biology 6 48 English CHIM/06
Optional
Biomembranes 6 48 English BIO/09
Developmental Biology and Genetics 6 48 English BIO/18
Functional Genomics 6 48 English BIO/11 BIO/18
Molecular Microbiology and Genetics of Microorganisms 6 48 English BIO/18 BIO/19
Molecular Pharmacology and Immunology 6 48 English BIO/14 MED/04
Synthetic Biology 6 48 English BIO/04 BIO/10 BIO/11 BIO/18 BIO/19
Second semester
Courses or activities ECTS Total hours Language SSD
Compulsory
Molecular Genetics 6 48 English BIO/18
Protein Biochemistry 6 48 English BIO/10
Structural Biology of the Cell 6 48 English BIO/01 BIO/06
Optional
Biostatistics 6 48 English BIO/11 BIO/18
Epigenetics and Epigenomics 6 48 English BIO/11 BIO/18
Methods in Biochemical Investigation 6 48 English BIO/10
Signal Transduction 6 48 English BIO/04 BIO/10
Stem Cells and Genetic Diseases 6 48 English BIO/14
Open sessions
There are no specific sessions for these activities (e.g. open online courses).
Courses or activities ECTS Total hours Language SSD
Optional
Additional Language Skills: Italian (3 ECTS) 3 0 Italian
be activated by the A.Y. 2026/2027
year
Courses or activities ECTS Total hours Language SSD
Compulsory
Biomolecular Methods Laboratory 9 72 English BIO/10 BIO/11 BIO/18
Open sessions
There are no specific sessions for these activities (e.g. open online courses).
Courses or activities ECTS Total hours Language SSD
Compulsory
Laboratory Training 9 0 English
Conclusive activities
There are no specific sessions for these activities (e.g. open online courses).
Courses or activities ECTS Total hours Language SSD
Compulsory
Final Dissertation 30 0 English
There are no propaedeutic courses in the MBC programme that limit progression from the first to the second year.
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Laboratory locations
Classrooms are located in the University buildings in: Via Celoria, 26 (Biology buildings); Via Celoria, 20 (Teaching Sector); Via Golgi, 19. Most laboratories are located in the Department of Biosciences, Via Celoria 26, 20133 Milano.
Head of study programme
Erasmus and international mobility tutor 
Master's degree admission tutor
Credit recognition tutor
Reference structures
Contacts

The tuition fees for students enrolled in Bachelor's, Master's and single-cycle degree programmes are divided into two instalments with different calculation methods and payment schedules:

  • The amount of the first instalment is the same for all students
  • The amount of the second instalment varies according to the ISEE University value, the degree programme and the student status (on track / off track for one year or off track for more than a year) 
  • An additional fee is due for online programmes

The University also offers:

  • Concessions for students meeting high merit requirements
  • Diversified tuition fees according to the student's home country for international students with assets/income abroad
  • Concessions for international students with refugee status

Scholarships and benefits

The University provides a range of financial benefits to students meeting special requirements (merit, financial or personal conditions, international students).

Learn more