Molecular and Cellular Pharmacology and Experimental Pharmacology
A.Y. 2024/2025
Learning objectives
The objective of the course is:
- To acquire knowledge about the main pharmacological targets at cellular and molecular level.
- To acquire knowledge about the most relevant in vitro and in vivo experimental models of preclinical pharmacology
- To acquire knowledge about the most relevant experimental techniques of preclinical pharmacology
- To acquire knowledge about the main pharmacological targets at cellular and molecular level.
- To acquire knowledge about the most relevant in vitro and in vivo experimental models of preclinical pharmacology
- To acquire knowledge about the most relevant experimental techniques of preclinical pharmacology
Expected learning outcomes
At the end of the course, the student will have to know
- the molecular and cellular mechanisms in which the main pharmacological targets are involved
- the techniques available to characterize such biological pathways.
- the main fundamentals of experimental and preclinical pharmacology
- the main techniques used in experimental pharmacology laboratories
- the molecular and cellular mechanisms in which the main pharmacological targets are involved
- the techniques available to characterize such biological pathways.
- the main fundamentals of experimental and preclinical pharmacology
- the main techniques used in experimental pharmacology laboratories
Lesson period: Second semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Lesson period
Second semester
Prerequisites for admission
Notions of pharmacology are required to adequately address the content covered in the course.
Assessment methods and Criteria
Written exam (15 multiple-choice questions, 2 points for each correct answer) and oral presentation of a scientific publication. The final grade is the average of the marks from the written exam and oral presentation.
Molecular and Cellular Pharmacology
Course syllabus
Study of the main pharmacological targets: receptors and channels, structure and function, post-translational modifications, enzymes, proteases and adhesion molecules, synaptic plasticity mechanisms.
Teaching methods
Lectures (16 hours) and laboratory of preclinical pharmacology (32 hours).
Teaching Resources
Slides and other material provided by the professor
Experimental Pharmacology
Course syllabus
Use of PubMed, Entrez, UniProt and other related websites for protein and gene analysis. Scientific publications. Research integrity. In vitro methods of experimental pharmacology: use and manipulation of cell lines and primary cultures. Human induced pluripotent stem cells (iPSCs) and their use as disease model. Organoids. Molecular biology techniques and CRISPR/Cas9.
Use of animal models of different diseases. Analysis of behavioral experiments.
Microscopy: from traditional fluorescence microscopy to confocal microscopy.
Study of protein-protein interaction.
Use of animal models of different diseases. Analysis of behavioral experiments.
Microscopy: from traditional fluorescence microscopy to confocal microscopy.
Study of protein-protein interaction.
Teaching methods
Frontal lectures (16 hours) and laboratory of preclinical pharmacology (32 hours)
Teaching Resources
Slides and other material provided by the lecturer.
Experimental Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Practicals: 32 hours
Lessons: 16 hours
Lessons: 16 hours
Professor:
Marcello Elena
Shifts:
Turno
Professor:
Marcello Elena
Molecular and Cellular Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Practicals: 32 hours
Lessons: 16 hours
Lessons: 16 hours
Professors:
Pelucchi Silvia Cecilia, Scheggia Diego
Shifts:
Professor(s)