General Pathology and Pathophysiology
A.Y. 2024/2025
Learning objectives
The main objective of this course will be to study the pathological mechanisms beyond the systemic diseases paying special attention on etiology (cause of the disease) and pathogenesis (origin and development of a disease) of the pathological processes. General topics which will be covered include the nature and causes of cell injury and death; adaptive cellular changes; apoptosis and necrosis, inflammation, healing and repair, immune system, neoplasia, liver damage and diabetes.
Expected learning outcomes
To understand pathological mechanisms related cell injury and death, adaptive cellular changes, apoptosis and necrosis, inflammation, healing and repair, immune system, and neoplasia.
To discriminate etiology and pathological mechanisms related to plant extracts.
Use the terminology for the field of pathology correctly and contextually.
To acquire the ability to relate these essential basic pathological processes to the pathogenesis of common and important diseases, e.g. neoplasia and inflammation
To discriminate etiology and pathological mechanisms related to plant extracts.
Use the terminology for the field of pathology correctly and contextually.
To acquire the ability to relate these essential basic pathological processes to the pathogenesis of common and important diseases, e.g. neoplasia and inflammation
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
Single session
Responsible
Lesson period
First semester
Course syllabus
- Etiology and pathogenesis
- Cholera, sickle cell anemia, cystic fibrosis
- Cellular damages
- Atrophy and hypertrophy
- Hyperplasia
- Metaplasia
- Steatosis
- Amyloidosis
- Necrosis and apoptosis
- Neoplasia
- Angiogenesis
- Carcinogenesis
- Immunological system
- Prions
- Alzheimer
- Diabetes (type 1, type 2 and gestational)
- Obesity and metabolic syndrome
- Hepatitis
- Haematopoiesis
- Hypertension
- Immunity (innate and acquired)
- Cholera, sickle cell anemia, cystic fibrosis
- Cellular damages
- Atrophy and hypertrophy
- Hyperplasia
- Metaplasia
- Steatosis
- Amyloidosis
- Necrosis and apoptosis
- Neoplasia
- Angiogenesis
- Carcinogenesis
- Immunological system
- Prions
- Alzheimer
- Diabetes (type 1, type 2 and gestational)
- Obesity and metabolic syndrome
- Hepatitis
- Haematopoiesis
- Hypertension
- Immunity (innate and acquired)
Prerequisites for admission
Physiology: endocrine system, cardiovascular system, lymphatic system.
Anatomy: The liver, the pancreas, the thyroid.
Molecular biology: proteasome, cell cycle.
Anatomy: The liver, the pancreas, the thyroid.
Molecular biology: proteasome, cell cycle.
Teaching methods
Standard teacher-based lessons.
Teaching Resources
- All the slides are present on the Ariel webpage
- Fabio Celotti, Patologia Generale e Fisiopatologia, II Edizione, Edises, 2013
- Kumar, Robbins Fondamenti di Patologia e di Fisiopatologia, Edra, 2013
- Pontieri, Elementi di Patologia Generale e Fisiopatologia Generale, Piccin, 2012
- Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai: Immunologia cellulare e molecolare. Elsevier Ed
- Fabio Celotti, Patologia Generale e Fisiopatologia, II Edizione, Edises, 2013
- Kumar, Robbins Fondamenti di Patologia e di Fisiopatologia, Edra, 2013
- Pontieri, Elementi di Patologia Generale e Fisiopatologia Generale, Piccin, 2012
- Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai: Immunologia cellulare e molecolare. Elsevier Ed
Assessment methods and Criteria
Oral test to evaluate students' knowledge of the fundamental concepts of the subject. Positive marks range from 18 to 30; e.g., 18/30 (the lowest mark) or 30/ 30 cum laude (the highest mark).
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 6
Lessons: 48 hours
Professor:
Ruscica Massimiliano
Educational website(s)
Professor(s)