Developmental Biology
A.Y. 2024/2025
Learning objectives
The course will introduce the student to the most important aspects of animal and plant developmental biology from fertilization to morphogenesis and the use of different model organisms.
Expected learning outcomes
At the end of the course, the student will acquire:
- the correct terminology related to the development of animal and plant organisms;
- the main genetic, molecular and cellular mechanisms that determine animal and plant development;
the main cellular and molecular techniques and the model organisms used in the study of animal and plant developmental biology
- the correct terminology related to the development of animal and plant organisms;
- the main genetic, molecular and cellular mechanisms that determine animal and plant development;
the main cellular and molecular techniques and the model organisms used in the study of animal and plant developmental biology
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
A - L
Responsible
Lesson period
First semester
Course syllabus
Animal Developmental Biology
An introduction to Developmental Biology: from egg to embryo. Cellular and molecular techniques for the study of development. Egg and sperm cells: structure of gametes and gametogenesis. Fertilization: species-specific interaction, cellular and molecular mechanisms regulating sperm-egg interaction. Embryonic development: maternal inheritance, cleavage, gastrulation and outlines of organogenesis. The three germ layers: ectoderm, mesoderm and endoderm. Morphogenesis of the Central Nervous System. Regeneration.
Animal models: Drosophila, Zebrafish, Xenopus, Chick and Mouse. Embryonic axes: the lesson from the Drosophila embryo.
The paradigm of differential gene expression. Homeobox genes and body plan. Stem Cells. Medical Embryology.
Plant Developmental biology:
The differences and similarities between Plant and animal developmental biology; Plant model organisms; Differentiation mechanisms: asymmetric cell divisions, transcriptional regulation and morphogen gradients; Fertilization (formation of male and female gametes - double fertilization process); Embryo development (embryogenesis); Phytohormones; Apical meristem; Radical meristem; Axillary meristems and lateral organ development (primordial position and morphology); Interactions between plant and environment; examples of organogenesis: the root and the flower.
An introduction to Developmental Biology: from egg to embryo. Cellular and molecular techniques for the study of development. Egg and sperm cells: structure of gametes and gametogenesis. Fertilization: species-specific interaction, cellular and molecular mechanisms regulating sperm-egg interaction. Embryonic development: maternal inheritance, cleavage, gastrulation and outlines of organogenesis. The three germ layers: ectoderm, mesoderm and endoderm. Morphogenesis of the Central Nervous System. Regeneration.
Animal models: Drosophila, Zebrafish, Xenopus, Chick and Mouse. Embryonic axes: the lesson from the Drosophila embryo.
The paradigm of differential gene expression. Homeobox genes and body plan. Stem Cells. Medical Embryology.
Plant Developmental biology:
The differences and similarities between Plant and animal developmental biology; Plant model organisms; Differentiation mechanisms: asymmetric cell divisions, transcriptional regulation and morphogen gradients; Fertilization (formation of male and female gametes - double fertilization process); Embryo development (embryogenesis); Phytohormones; Apical meristem; Radical meristem; Axillary meristems and lateral organ development (primordial position and morphology); Interactions between plant and environment; examples of organogenesis: the root and the flower.
Prerequisites for admission
It is recommended to have acquired basic skills in genetics, cellular and molecular biology
Teaching methods
Teaching method based on interactive frontal lessons supported by projected material (slides as power point presentations). Students will be stimulated to actively participate in the lesson / discussion to improve their critical skills, analyzing the literature and communicating the concepts in appropriate way. Frequency mode: strongly
Teaching Resources
Slides of the lectures in the Ariel website of the teacher
Gilbert SF Developmental Biology Zanichelli
Altamura et al., Elementi di Biologia dello Sviluppo delle piante Edises
Gilbert SF Developmental Biology Zanichelli
Altamura et al., Elementi di Biologia dello Sviluppo delle piante Edises
Assessment methods and Criteria
The exam consists of a written assignment with open and multiple choice questions. The student will also be given the opportunity to improve the final score with a subsequent oral interview. The exam aims to evaluate the knowledge acquired and the student's ability to solve biological problems based on the topics covered in the course.
BIO/01 - GENERAL BOTANY - University credits: 3
BIO/06 - COMPARATIVE ANATOMY AND CYTOLOGY - University credits: 3
BIO/06 - COMPARATIVE ANATOMY AND CYTOLOGY - University credits: 3
Lessons: 48 hours
Professors:
Biffo Stefano, Colombo Lucia
M - Z
Responsible
Lesson period
First semester
Course syllabus
Animal Developmental Biology
An introduction to Developmental Biology: from egg to embryo. Cellular and molecular techniques for the study of development. Egg and sperm cells: structure of gametes and gametogenesis. Fertilization: species-specific interaction, cellular and molecular mechanisms regulating sperm-egg interaction. Embryonic development: maternal inheritance, cleavage, gastrulation and outlines of organogenesis. The three germ layers: ectoderm, mesoderm and endoderm. Morphogenesis of the Central Nervous System. Regeneration.
Animal models: Drosophila, Zebrafish, Xenopus, Chick and Mouse. Embryonic axes: the lesson from the Drosophila embryo.
The paradigm of differential gene expression. Homeobox genes and body plan. Stem Cells. Medical Embryology.
Plant Developmental biology:
The differences and similarities between Plant and animal developmental biology; Plant model organisms; Differentiation mechanisms: asymmetric cell divisions, transcriptional regulation and morphogen gradients; Fertilization (formation of male and female gametes - double fertilization process); Embryo development (embryogenesis); Phytohormones; Apical meristem; Radical meristem; Axillary meristems and lateral organ development (primordial position and morphology); Interactions between plant and environment; examples of organogenesis: the root and the flower.
An introduction to Developmental Biology: from egg to embryo. Cellular and molecular techniques for the study of development. Egg and sperm cells: structure of gametes and gametogenesis. Fertilization: species-specific interaction, cellular and molecular mechanisms regulating sperm-egg interaction. Embryonic development: maternal inheritance, cleavage, gastrulation and outlines of organogenesis. The three germ layers: ectoderm, mesoderm and endoderm. Morphogenesis of the Central Nervous System. Regeneration.
Animal models: Drosophila, Zebrafish, Xenopus, Chick and Mouse. Embryonic axes: the lesson from the Drosophila embryo.
The paradigm of differential gene expression. Homeobox genes and body plan. Stem Cells. Medical Embryology.
Plant Developmental biology:
The differences and similarities between Plant and animal developmental biology; Plant model organisms; Differentiation mechanisms: asymmetric cell divisions, transcriptional regulation and morphogen gradients; Fertilization (formation of male and female gametes - double fertilization process); Embryo development (embryogenesis); Phytohormones; Apical meristem; Radical meristem; Axillary meristems and lateral organ development (primordial position and morphology); Interactions between plant and environment; examples of organogenesis: the root and the flower.
Prerequisites for admission
It is recommended to have acquired basic skills in cellular and molecular biology
Teaching methods
Teaching method based on interactive frontal lessons supported by projected material (slides as power point presentations). Students will be stimulated to actively participate in the lesson / discussion to improve their critical skills, analyzing the literature and communicating the concepts in appropriate way. Frequency mode: strongly recommended
Teaching Resources
Slides of the lectures in the Ariel website of the teacher
Gilbert SF Developmental Biology Zanichelli
Altamura et al., Elementi di Biologia dello Sviluppo delle piante Edises
Gilbert SF Developmental Biology Zanichelli
Altamura et al., Elementi di Biologia dello Sviluppo delle piante Edises
Assessment methods and Criteria
The exam consists of a written assignment with open and multiple choice questions. The student will also be given the opportunity to improve the final score with a subsequent oral interview. The exam aims to evaluate the knowledge acquired and the student's ability to solve biological problems based on the topics covered in the course.
BIO/01 - GENERAL BOTANY - University credits: 3
BIO/06 - COMPARATIVE ANATOMY AND CYTOLOGY - University credits: 3
BIO/06 - COMPARATIVE ANATOMY AND CYTOLOGY - University credits: 3
Lessons: 48 hours
Professors:
Messina Graziella, Miranda Mendes Marta Adelina
Educational website(s)
Professor(s)
Reception:
On appointment (email)
Torre C 7th floor