Toxicology 2

The objective of the teaching is to introduce students to the main classes of xenobiotics (molecules of natural and synthetic origin) that exert toxic effects on humans, with special emphasis on anthropogenic pollutants and molecules with pharmacological action. The conditions of exposure are examined, the effects on the organism are described, and the molecular mechanisms underlying the toxicity of the substances under investigation are analyzed. Students are encouraged to critically analyze data available in databases, experimental, occupational, and epidemiological, on the health and environmental risk associated with exposure to toxic substances. In addition, students, through laboratory exercises, are introduced to basic methodologies aimed at evaluating the biological effects of toxic substances in experimental models.

Upon completion of the course, the student will have acquired adequate knowledge of the toxic effects of natural and anthropogenic molecules and the mechanisms underlying these effects. The student will also be able to critically address toxicological issues based on available data: experimental, occupational and epidemiological. The student will also be able to deal with basic experimental methodologies for the evaluation of biological effects of toxic substances.