Research Methods in Rehabilitation
A.Y. 2024/2025
Learning objectives
The course is aimed at providing students with knowledge about: - medical ethics, in order to develop critical thinking and discussion skills on moral, legal and ethical issues related to health professions; - theories and statistical-psychometric methods
Expected learning outcomes
At the end of the course, the student will be able to:
- assess educational needs, identify effective operational tools and educational strategies in order to design training interventions according to the characteristics and needs of the trainees
- assess educational needs, identify effective operational tools and educational strategies in order to design training interventions according to the characteristics and needs of the trainees
Lesson period: Second semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
Single session
Responsible
Prerequisites for admission
Basic knwoldege of descriptive statistic
Assessment methods and Criteria
The learning assessment takes place through a written test, organized in specific exam sessions, as per the Regulations.
Up to a maximum of six exam sessions may be scheduled for each academic year: two in each session.
The typology of the test is written (multiple choice quiz) with 31 closed questions with the choice between five answers, only one of which is correct; each correct question is worth one point; all correct questions give an evaluation of 30 Lode.
The total time of the written test is 45 minutes.
The exams of all the modules of the Rehabilitation Research Methodology course are carried out together on the same day and contribute equally to determining the final evaluation expressed in thirtieths with the mathematical average of the partial grades.
The questions refer to the slides presented in the classroom and available in ARIEL, to the recommended texts and to the bibliography provided by the teacher.
No intermediate or early exam sessions are planned.
Didactic materials or notes are not admitted for the test.
The results are published online on the course's ARIEL website and students can view the test upon request.
The exam is recorded using the University's online procedure.
Up to a maximum of six exam sessions may be scheduled for each academic year: two in each session.
The typology of the test is written (multiple choice quiz) with 31 closed questions with the choice between five answers, only one of which is correct; each correct question is worth one point; all correct questions give an evaluation of 30 Lode.
The total time of the written test is 45 minutes.
The exams of all the modules of the Rehabilitation Research Methodology course are carried out together on the same day and contribute equally to determining the final evaluation expressed in thirtieths with the mathematical average of the partial grades.
The questions refer to the slides presented in the classroom and available in ARIEL, to the recommended texts and to the bibliography provided by the teacher.
No intermediate or early exam sessions are planned.
Didactic materials or notes are not admitted for the test.
The results are published online on the course's ARIEL website and students can view the test upon request.
The exam is recorded using the University's online procedure.
Sistemi di elaborazioni delle informazioni Modulo
Course syllabus
- Technological tools and equipment that can assess and quantify functional damage: motion analysis, inertial
sensors, sensor prostheses; Robotics and virtual reality in rehabilitation; Skeletal muscle modelling: simulation of
movement based on data collected by the patient.
- Planning of functional surgery, applications of neuromuscular electrical stimulation
The system of European research organization in rehabilitation.
sensors, sensor prostheses; Robotics and virtual reality in rehabilitation; Skeletal muscle modelling: simulation of
movement based on data collected by the patient.
- Planning of functional surgery, applications of neuromuscular electrical stimulation
The system of European research organization in rehabilitation.
Teaching methods
The teaching consists of frontal classroom lessons, scheduled according to a timetable published on the ARIEL website of the master degree
Teaching Resources
Slides and learning material provided by the teacher
Patologia generale
Course syllabus
Natural immunity response
- Natural immunity cells
- Cell modifications during the response of natural immunity: Cellular activation (prr, nfkb and its adjustment);
Macrophage activation (m1, m2)
- Vascular changes during natural immunity: Vasodilation; Increased permeability
- Leucocitary recruitment: Membership (molecules involved)
ChemotaxIs
- Mediators
- Chronic inflammatory response
- Adenosine; Functions of adenosine
Tumors
- Benign tumor and malignant tumor; Genes involved in the genesis of cancer; Molecular bases of oncology;
Characteristics of the cancer cell: neoplastic progression; Angiogenesis; TranscriptIon Factor hypoxia
inducible factor 1: adjustment
- Techniques described: Cell cultures; Western blot, qualitative and quantitative analysis of protein
- Natural immunity cells
- Cell modifications during the response of natural immunity: Cellular activation (prr, nfkb and its adjustment);
Macrophage activation (m1, m2)
- Vascular changes during natural immunity: Vasodilation; Increased permeability
- Leucocitary recruitment: Membership (molecules involved)
ChemotaxIs
- Mediators
- Chronic inflammatory response
- Adenosine; Functions of adenosine
Tumors
- Benign tumor and malignant tumor; Genes involved in the genesis of cancer; Molecular bases of oncology;
Characteristics of the cancer cell: neoplastic progression; Angiogenesis; TranscriptIon Factor hypoxia
inducible factor 1: adjustment
- Techniques described: Cell cultures; Western blot, qualitative and quantitative analysis of protein
Teaching methods
The teaching consists of frontal classroom lessons, scheduled according to a timetable published on the ARIEL website of the master degree
Teaching Resources
Pontieri, Elementi di patologia generale. Per i corsi di laurea in professioni sanitarie. Piccin, 2018
Rubin, Reisner, Rizzuto, Ausoni, Patologia generale: l'essenziale. Piccin 2015
Cairo, Recalcati, Tacchini, Quick review: patologia. Edises 2011
Rubin, Reisner, Rizzuto, Ausoni, Patologia generale: l'essenziale. Piccin 2015
Cairo, Recalcati, Tacchini, Quick review: patologia. Edises 2011
Oncologia
Course syllabus
- Fundamentals of clinical research (hypothesis, experimental phase, discussion of results)
- Epidemiology and risk factors of tumors
- Diagnostic Procedure, screening test in oncology
- Value of clinical trials, observational and experimental trials, cohort study, study with historical control group, randomized studies
- Phase I clinical studies: objectives, methods, interpretation of results
- Phase II clinical studies: objectives, methods (Simon test, clinical response assessment), interpretation of results
- Phase III clinical studies: objectives, methods (Survival evaluation, median Survival), interpretation of results
- Phase IV studies
- Studies with historical controls: limits and advantages
- Non inferiority studies
- Meta-analysis: limits and advantages
- Planning a clinical trial (ethical committee, inclusion and exclusion criteria, informed consent)
- the basics of cancer immunology
- immune checkpoint inhibitors
- writing a project for a clinical research grant
- planning of a clinical trial from design to dissemination
- personalized and gender medicine
- how to present the results of the research project at a conference (posters, oral communications)
- how to write a scientific paper
- the EQUATOR network guidelines for the different types of study
- Epidemiology and risk factors of tumors
- Diagnostic Procedure, screening test in oncology
- Value of clinical trials, observational and experimental trials, cohort study, study with historical control group, randomized studies
- Phase I clinical studies: objectives, methods, interpretation of results
- Phase II clinical studies: objectives, methods (Simon test, clinical response assessment), interpretation of results
- Phase III clinical studies: objectives, methods (Survival evaluation, median Survival), interpretation of results
- Phase IV studies
- Studies with historical controls: limits and advantages
- Non inferiority studies
- Meta-analysis: limits and advantages
- Planning a clinical trial (ethical committee, inclusion and exclusion criteria, informed consent)
- the basics of cancer immunology
- immune checkpoint inhibitors
- writing a project for a clinical research grant
- planning of a clinical trial from design to dissemination
- personalized and gender medicine
- how to present the results of the research project at a conference (posters, oral communications)
- how to write a scientific paper
- the EQUATOR network guidelines for the different types of study
Teaching methods
Lectures
Tutorials
Flipped classroom
Tutorials
Flipped classroom
Teaching Resources
Slide and references provided by the teacher
Scienze infermieristiche e tecniche neuropsichiatriche e riabilitative
Course syllabus
Defining research aims according to clinical needs
Experimental designs and bias in rehabilitation
Quasi-Experimental designs
AB or "single system design"
Observational studies
Experimental studies in rehabilitation: examples from the field
Research grants:
Grant selection
The research group
Main characteristics:
Introduction
experimental hypotheses
Aims
Material and Methods
Sample size and data analysis
Significance and Innovation
Relevance
Experimental designs and bias in rehabilitation
Quasi-Experimental designs
AB or "single system design"
Observational studies
Experimental studies in rehabilitation: examples from the field
Research grants:
Grant selection
The research group
Main characteristics:
Introduction
experimental hypotheses
Aims
Material and Methods
Sample size and data analysis
Significance and Innovation
Relevance
Teaching methods
The teaching consists of frontal classroom lessons and group discussion on key documents with and without digital tools. Teaching is scheduled according to a timetable published on the ARIEL website of the master degree.
Teaching Resources
Slide e bibliografia a cura del docente
Materiale Facoltativo: Leslie Gross Portney, Mary P. Watkins. Foundations of Clinical Research: Applications to Practice, 3rd Edition - Part 3 - Portney & Watkins ©2000
Materiale Facoltativo: Leslie Gross Portney, Mary P. Watkins. Foundations of Clinical Research: Applications to Practice, 3rd Edition - Part 3 - Portney & Watkins ©2000
Filosofia morale
Course syllabus
Part 1: Ethics
- Philosophical ethics and role ethics
- content and function of ethical codes in the health professions.
Part 2 - Medical bioethics
- Health rights, informed consent
- role of Ethics Committees as concerns healthcare treatments and biomedical research
- Philosophical ethics and role ethics
- content and function of ethical codes in the health professions.
Part 2 - Medical bioethics
- Health rights, informed consent
- role of Ethics Committees as concerns healthcare treatments and biomedical research
Teaching methods
The teaching consists of frontal classroom lessons, scheduled according to a timetable published on the ARIEL website of the master degree
Teaching Resources
-C. Del Bò, Etica del turismo, Carocci, 2017, only chapter 2.
-material is distributed in class.
-material is distributed in class.
Psicometria
Course syllabus
1)The stages of scientific research (2 LESSONS)
2) Validity of research (1 LESSON)
3) Validity and reliability of measurement. Concept of quantification and measurement: overview of measurement scales and tests (2 LESSONS)
4) Experimental and non-experimental and clinical research (3 LESSONS)
2) Validity of research (1 LESSON)
3) Validity and reliability of measurement. Concept of quantification and measurement: overview of measurement scales and tests (2 LESSONS)
4) Experimental and non-experimental and clinical research (3 LESSONS)
Teaching methods
Lectures and group exercises.
Teaching Resources
Materials provided by the teacher.
Filosofia morale
M-FIL/03 - MORAL PHILOSOPHY - University credits: 1
Lessons: 8 hours
Professor:
Ferraro Francesco
Oncologia
MED/06 - MEDICAL ONCOLOGY - University credits: 1
Lessons: 8 hours
Professors:
Gualtierotti Roberta, Guidetti Anna
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 1
Lessons: 8 hours
Professor:
Gammella Elena
Psicometria
M-PSI/03 - PSYCHOMETRICS - University credits: 2
Lessons: 16 hours
Professor:
Mangialavori Sonia
Scienze infermieristiche e tecniche neuropsichiatriche e riabilitative
MED/48 - NURSING IN NEUROPSYCHIATRY AND REHABILITATION - University credits: 1
Lessons: 8 hours
Professor:
Cattaneo Davide
Sistemi di elaborazioni delle informazioni Modulo
ING-INF/05 - INFORMATION PROCESSING SYSTEMS - University credits: 1
Lessons: 8 hours
Professor:
Cattaneo Davide
Educational website(s)
Professor(s)
Reception:
Wednesday from 11am to 4pm
Larice Lab - IRCCS Fondazione Don Carlo Gnocchi - Via Capecelatro 66, Milan
Reception:
By appointment via e-mail
Reception:
On Thursdays, at 3 p.m.
CET, via Pace 9 Milano, Pad 2, first floor