Organic Chemistry 2 and Organic Chemistry Laboratory

Therotical course:
1 - Aromatic compounds. Chemistry of benzene and naphtalene, aromaticity, mechanisms of electrophilic and nucleophilic substitution, activating, deactivating and orienting effects of substituting groups. Understanding of the main reactions of synthetic value. Some classes of compounds will be developed taking into account their specific importance.
2 - Chemistry of sulfur containing compounds
3- Enols, enolates, enamines, electron-poor alkenes, quinones: kinetics and thermodynamics of enolization processes, formation and stability of enolates and enamines; synthetic applications of aldol condensation reactions, Claisen condensation reactions, alkylation processes. Theory and use of the reactivity of eletron-poor alkenes.
4 - Heterocyclic compounds. A general picture of the reactivity of several important heterocyclic rings will be given to the student taking into account those essential for his career. Main synthetic pathways will be explained.
5 - Amino acids and peptides: properties of amino acids, their synthesis, protecting groups and principles of peptide synthesis.
6 - Exercises. Theoretical and practical problems will be proposed to the student and solved by direct free discussion.

Laboratory course:
Practical experiences are preceded by the necessary theoretical explanations. - Realization of simple Organic Chemistry syntheses and learning of fundamental purification techniques: a) condensation; b) oxidation; c) multicomponent reaction; d) nucleophilic acyl substitution. All the syntheses are followed and controlled with the most appropriate analytical techniques and all the products obtained are subjected to adequate purification and characterization processes.

1 - Aromatic compounds. Chemistry of benzene and naphtalene, aromaticity, mechanisms of electrophilic and nucleophilic substitution, activating, deactivating and orienting effects of substituting groups. Understanding of main reactions of synthetic value. Some classes of compounds will be developed taking into account their specific importance.
2 - Chemistry of sulfur containing compounds
3- Enols, enolates, enamines, electron-poor alkenes, quinones: kinetics and thermodynamics of enolization processes, formation and stability of enolates and enamines; synthetic applications of aldol condensation reactions, Claisen condensation reactions, alkylation processes. Theory and use of the reactivity of eletronpoor alkenes.
4 - Heterocyclic compounds. A general picture of the reactivity of several important heterocyclic rings will be given to the student taking into account those essential for his career. Main synthetic pathways will be explained.
5 - Amino acids and peptides: properties of amino acids, their synthesis, protecting groups and principles of peptide synthesis.
6 - Exercises. Theoretical and practical problems will be proposed to the student and solved by direct free discussion.
Laboratory course:
Practical experiences are preceded by the necessary theoretical explanations. - Realization of simple Organic Chemistry syntheses and learning of fundamental purification techniques: a) condensation; b) oxidation; c) multicomponent reaction; d) nucleophilic acyl substitution. All the syntheses are followed and controlled with the most appropriate analytical techniques and all the products obtained are subjected to adequate purification and characterization processes.