Organic Chemistry 1
A.Y. 2024/2025
Learning objectives
The objectives of the Organic Chemistry 1 course are aimed at the learning, by the student, of the fundamental principles of organic chemistry: from the nature of chemical bonds to the molecular structure, from the shape of the molecules to the stereochemistry up to the study of the reactivity of the organic compounds based on the nature of their functional groups. Therefore, the ability to recognize functional groups, the understanding of reaction mechanisms and the critical evaluation of related stereochemical aspects are the fundamental objectives of teaching. The purpose of this course is to provide a reasoning method to facilitate the learning of the basic notions. In this regard there will be numerous examples of practical application of the concepts taught and the lessons will be accompanied by exercises on the blackboard with the aim of deepening and assimilating the topics covered in the theoretical lessons.
Expected learning outcomes
At the end of the course, students must be able to: - acquire the appropriate terminology to name the molecules and describe their reactivity; discuss the mechanisms of organic reactions applied to specific substrates; propose synthetic routes for the construction of simple organic molecules; - possess the ability to present their knowledge in a clear and orderly manner, with appropriate scientific language and with rigorous arguments.
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
Linea AK
Responsible
Lesson period
First semester
Course syllabus
Chemical bonding and structure: Ionic and covalent bonds; polarity. Structures and formulas of organic molecules. Resonance structures. Acid-base equilibrium. Functional groups in organic chemistry.
Alkanes. Naming, conformational isomerism, Newman projections, kinetics and thermodynamics of conformational isomerism. Reactions of alkanes. Alogenation, alkyl radicals, hyperconjugation. Combustion. Cyclic alkanes. Naming; ring strain. Substituted cyclohexanes and conformational considerations.
Stereochemistry. Chiral molecules; optical activity; absolute configurations and R-S sequence rules; Fischer projections. Molecules with several stereocenters: diastereomers and meso compounds. Stereochemistry in chemical reactions; resolution of enantiomers.
Haloalkanes. Naming. Nucleophilic substitution SN2 and SN1: kinetics, stereochemistry, leaving group ability, solvent effects, relative stability of carbocations. Elimination reactions E1 and E2. Organometallic compounds: preparation and reactivity.
Alcohols. Naming. Alcohols as acids and bases. Synthesis by nucleophilic substitution or organometallic reagents. Alkoxide. Oxidations.
Ethers. Naming, synthesis and reactivity.
Alkenes. Naming, structure and E/Z isomerism; relative stability and heat of hydrogenation. Synthesis and reactivity. Synthesis and reactivity of oxiranes.
Alkynes. Naming, acidity. Synthesis and reactivity.
Delocalized systems. Allylic system and conjugated dienes. Diels-Alder reaction. Benzene and aromaticity.
Aldehydes and ketones. Naming, structure of carbonyl group. Synthesis. Reactions of nucleophilic additions; oxidations and reductions.
Carboxylic acids and derivatives. Naming and acidity. Synthesis and reactivity. Dicarboxylic acids. Esters, anhydrides, acid chlorides, amides, nitriles.
Alkylamines. Naming. Basicity. Synthesis and reactivity.
Carbohydrates. Structures, classification, configuration. Mutarotation. Reactivity.
Alkanes. Naming, conformational isomerism, Newman projections, kinetics and thermodynamics of conformational isomerism. Reactions of alkanes. Alogenation, alkyl radicals, hyperconjugation. Combustion. Cyclic alkanes. Naming; ring strain. Substituted cyclohexanes and conformational considerations.
Stereochemistry. Chiral molecules; optical activity; absolute configurations and R-S sequence rules; Fischer projections. Molecules with several stereocenters: diastereomers and meso compounds. Stereochemistry in chemical reactions; resolution of enantiomers.
Haloalkanes. Naming. Nucleophilic substitution SN2 and SN1: kinetics, stereochemistry, leaving group ability, solvent effects, relative stability of carbocations. Elimination reactions E1 and E2. Organometallic compounds: preparation and reactivity.
Alcohols. Naming. Alcohols as acids and bases. Synthesis by nucleophilic substitution or organometallic reagents. Alkoxide. Oxidations.
Ethers. Naming, synthesis and reactivity.
Alkenes. Naming, structure and E/Z isomerism; relative stability and heat of hydrogenation. Synthesis and reactivity. Synthesis and reactivity of oxiranes.
Alkynes. Naming, acidity. Synthesis and reactivity.
Delocalized systems. Allylic system and conjugated dienes. Diels-Alder reaction. Benzene and aromaticity.
Aldehydes and ketones. Naming, structure of carbonyl group. Synthesis. Reactions of nucleophilic additions; oxidations and reductions.
Carboxylic acids and derivatives. Naming and acidity. Synthesis and reactivity. Dicarboxylic acids. Esters, anhydrides, acid chlorides, amides, nitriles.
Alkylamines. Naming. Basicity. Synthesis and reactivity.
Carbohydrates. Structures, classification, configuration. Mutarotation. Reactivity.
Prerequisites for admission
The course is delivered to students who have acquired fundamental notions in General and Inorganic Chemistry.
Teaching methods
- Classroom lessons incorporating learning verification checkpoints
- Classroom exercises
- Online learning verification tests (via the Exam Manager app) conducted between lessons to monitor learning progress
- Classroom exercises
- Online learning verification tests (via the Exam Manager app) conducted between lessons to monitor learning progress
Teaching Resources
Textbooks:
1. P. Y. Bruice - Chimica Organica 3°ediz. it. - Ed. Edises - 2017
2. W.H. Brown et al. - Chimica Organica 7°ediz. it. - Ed. Edises - 2023
3. J. Mc Murry - Chimica Organica - ediz. it. su 8° ediz. ingl. - Ed. Piccin - 2012
4. M. Loudon - Chimica Organica - ediz. it. su 5° ediz. amer. - Ed. Edises - 2010
Exercise books:
1. D'Auria et al. - Guida ragionata allo svolgimento di esercizi di chimica organica - Ed. Loghia
2. Iverson - Guida alla soluzione dei problemi da Chimica Organica di Brown, Iverson, Anslyn, Foote - Ed. Edises
3. Broggini et al. - Chimica Organica 800 esercizi con soluzione - Zanichelli
On the instructor's MyAriel website, the following resources are available: lecture slides, exercises, videos, additional teaching materials, a list of relevant websites, a forum, and self-assessment tests.
1. P. Y. Bruice - Chimica Organica 3°ediz. it. - Ed. Edises - 2017
2. W.H. Brown et al. - Chimica Organica 7°ediz. it. - Ed. Edises - 2023
3. J. Mc Murry - Chimica Organica - ediz. it. su 8° ediz. ingl. - Ed. Piccin - 2012
4. M. Loudon - Chimica Organica - ediz. it. su 5° ediz. amer. - Ed. Edises - 2010
Exercise books:
1. D'Auria et al. - Guida ragionata allo svolgimento di esercizi di chimica organica - Ed. Loghia
2. Iverson - Guida alla soluzione dei problemi da Chimica Organica di Brown, Iverson, Anslyn, Foote - Ed. Edises
3. Broggini et al. - Chimica Organica 800 esercizi con soluzione - Zanichelli
On the instructor's MyAriel website, the following resources are available: lecture slides, exercises, videos, additional teaching materials, a list of relevant websites, a forum, and self-assessment tests.
Assessment methods and Criteria
The exam consists of a written test and an oral test.
- Written test: 10 exercises (practical applications of the theory) to be completed in two hours. Each exercise allows the acquisition of a score between zero and three points. Passing the written test, and therefore admission to the oral test is achieved upon reaching a total of 18 points.
- Oral test: it takes place after the time necessary for correcting the written test, on average about ten days, and concerns the theoretical topics covered in the course, reaction mechanisms, and the concepts underlying the exercises proposed in the written test. The final grade is formulated by the teacher by evaluating the student's overall preparation.
- Written test: 10 exercises (practical applications of the theory) to be completed in two hours. Each exercise allows the acquisition of a score between zero and three points. Passing the written test, and therefore admission to the oral test is achieved upon reaching a total of 18 points.
- Oral test: it takes place after the time necessary for correcting the written test, on average about ten days, and concerns the theoretical topics covered in the course, reaction mechanisms, and the concepts underlying the exercises proposed in the written test. The final grade is formulated by the teacher by evaluating the student's overall preparation.
CHIM/06 - ORGANIC CHEMISTRY - University credits: 10
Practicals: 16 hours
Lessons: 72 hours
Lessons: 72 hours
Professor:
Abbiati Giorgio
Shifts:
Turno
Professor:
Abbiati GiorgioLinea LZ
Responsible
Lesson period
First semester
Course syllabus
Chemical bonding and structure: Ionic and covalent bonds; polarity. Structures and formulas of organic molecules. Resonance structures. Acid-base equilibrium. Functional groups in organic chemistry.
Alkanes. Naming, conformational isomerism, Newman projections, kinetics and thermodynamics of conformational isomerism. Reactions of alkanes. Alogenation, alkyl radicals, hyperconjugation. Combustion. Cyclic alkanes. Naming; ring strain. Substituted cyclohexanes and conformational considerations.
Stereochemistry. Chiral molecules; optical activity; absolute configurations and R-S sequence rules; Fischer projections. Molecules with several stereocenters: diastereomers and meso compounds. Stereochemistry in chemical reactions; resolution of enantiomers.
Haloalkanes. Naming. Nucleophilic substitution SN2 and SN1: kinetics, stereochemistry, leaving group ability, solvent effects, relative stability of carbocations. Elimination reactions E1 and E2. Organometallic compounds: preparation and reactivity.
Alcohols. Naming. Alcohols as acids and bases. Synthesis by nucleophilic substitution or organometallic reagents. Alkoxide. Oxidations.
Ethers. Naming, synthesis and reactivity.
Alkenes. Naming, structure and E/Z isomerism; relative stability and heat of hydrogenation. Synthesis and reactivity. Synthesis and reactivity of oxiranes.
Alkynes. Naming, acidity. Synthesis and reactivity.
Delocalized systems. Allylic system and conjugated dienes. Diels-Alder reaction. Benzene and aromaticity.
Aldehydes and ketones. Naming, structure of carbonyl group. Synthesis. Reactions of nucleophilic additions; oxidations and reductions.
Carboxylic acids and derivatives. Naming and acidity. Synthesis and reactivity. Dicarboxylic acids. Esters, anhydrides, acid chlorides, amides, nitriles.
Alkylamines. Naming. Basicity. Synthesis and reactivity.
Carbohydrates. Structures, classification, configuration. Mutarotation. Reactivity.
Alkanes. Naming, conformational isomerism, Newman projections, kinetics and thermodynamics of conformational isomerism. Reactions of alkanes. Alogenation, alkyl radicals, hyperconjugation. Combustion. Cyclic alkanes. Naming; ring strain. Substituted cyclohexanes and conformational considerations.
Stereochemistry. Chiral molecules; optical activity; absolute configurations and R-S sequence rules; Fischer projections. Molecules with several stereocenters: diastereomers and meso compounds. Stereochemistry in chemical reactions; resolution of enantiomers.
Haloalkanes. Naming. Nucleophilic substitution SN2 and SN1: kinetics, stereochemistry, leaving group ability, solvent effects, relative stability of carbocations. Elimination reactions E1 and E2. Organometallic compounds: preparation and reactivity.
Alcohols. Naming. Alcohols as acids and bases. Synthesis by nucleophilic substitution or organometallic reagents. Alkoxide. Oxidations.
Ethers. Naming, synthesis and reactivity.
Alkenes. Naming, structure and E/Z isomerism; relative stability and heat of hydrogenation. Synthesis and reactivity. Synthesis and reactivity of oxiranes.
Alkynes. Naming, acidity. Synthesis and reactivity.
Delocalized systems. Allylic system and conjugated dienes. Diels-Alder reaction. Benzene and aromaticity.
Aldehydes and ketones. Naming, structure of carbonyl group. Synthesis. Reactions of nucleophilic additions; oxidations and reductions.
Carboxylic acids and derivatives. Naming and acidity. Synthesis and reactivity. Dicarboxylic acids. Esters, anhydrides, acid chlorides, amides, nitriles.
Alkylamines. Naming. Basicity. Synthesis and reactivity.
Carbohydrates. Structures, classification, configuration. Mutarotation. Reactivity.
Prerequisites for admission
The course is delivered to students who have acquired fundamental notions in General and Inorganic Chemistry
Teaching methods
- Classroom lessons incorporating learning verification checkpoints
- Classroom exercises
- Online learning verification tests (via the Exam Manager app) conducted between lessons to monitor learning progress
- Classroom exercises
- Online learning verification tests (via the Exam Manager app) conducted between lessons to monitor learning progress
Teaching Resources
Textbooks:
1. P. Y. Bruice - Chimica Organica 3°ediz. it. - Ed. Edises - 2017
2. W.H. Brown et al. - Chimica Organica 7°ediz. it. - Ed. Edises - 2023
3. J. Mc Murry - Chimica Organica - ediz. it. su 8° ediz. ingl. - Ed. Piccin - 2012
4. M. Loudon - Chimica Organica - ediz. it. su 5° ediz. amer. - Ed. Edises - 2010
Exercise books:
1. D'Auria et al. - Guida ragionata allo svolgimento di esercizi di chimica organica - Ed. Loghia
2. Iverson - Guida alla soluzione dei problemi da Chimica Organica di Brown, Iverson, Anslyn, Foote - Ed. Edises
3. Broggini et al. - Chimica Organica 800 esercizi con soluzione - Ed. Zanichelli
On the instructor's MyAriel website, the following resources are available: lecture slides, exercises, and, additional teaching materials,.
1. P. Y. Bruice - Chimica Organica 3°ediz. it. - Ed. Edises - 2017
2. W.H. Brown et al. - Chimica Organica 7°ediz. it. - Ed. Edises - 2023
3. J. Mc Murry - Chimica Organica - ediz. it. su 8° ediz. ingl. - Ed. Piccin - 2012
4. M. Loudon - Chimica Organica - ediz. it. su 5° ediz. amer. - Ed. Edises - 2010
Exercise books:
1. D'Auria et al. - Guida ragionata allo svolgimento di esercizi di chimica organica - Ed. Loghia
2. Iverson - Guida alla soluzione dei problemi da Chimica Organica di Brown, Iverson, Anslyn, Foote - Ed. Edises
3. Broggini et al. - Chimica Organica 800 esercizi con soluzione - Ed. Zanichelli
On the instructor's MyAriel website, the following resources are available: lecture slides, exercises, and, additional teaching materials,.
Assessment methods and Criteria
The exam consists of a written test and an oral test.
- Written test: 10 exercises (practical applications of the theory) to be completed in two hours. Each exercise allows the acquisition of a score between zero and three points. Passing the written test, and therefore admission to the oral test is achieved upon reaching a total of 18 points.
- Oral test: it takes place after the time necessary for correcting the written test, on average about ten days, and concerns the theoretical topics covered in the course, reaction mechanisms, and the concepts underlying the exercises proposed in the written test. The final grade is formulated by the teacher by evaluating the student's overall preparation.
- Written test: 10 exercises (practical applications of the theory) to be completed in two hours. Each exercise allows the acquisition of a score between zero and three points. Passing the written test, and therefore admission to the oral test is achieved upon reaching a total of 18 points.
- Oral test: it takes place after the time necessary for correcting the written test, on average about ten days, and concerns the theoretical topics covered in the course, reaction mechanisms, and the concepts underlying the exercises proposed in the written test. The final grade is formulated by the teacher by evaluating the student's overall preparation.
CHIM/06 - ORGANIC CHEMISTRY - University credits: 10
Practicals: 16 hours
Lessons: 72 hours
Lessons: 72 hours
Professor:
Pirovano Valentina
Shifts:
Turno
Professor:
Pirovano ValentinaProfessor(s)
Reception:
on appointment
DiSFarm - Sezione di Chimica Generale e Organica "A. Marchesini", via Venezian, 21 - Edificio 5, corpo A, 2° piano, stanza 2044