Human Anatomy (1 year)

A.Y. 2024/2025
12
Max ECTS
152
Overall hours
SSD
BIO/16
Language
Italian
Learning objectives
The aim of the Course of Macroscopic Human Morphology is to provide a map for self-guided learning and a tool for student success, managing to:
- define the terms relative to the anatomical position, the anatomical planes and the terms used to describe movement, so preparing the students to the correct knowledge and use of anatomical terms,
- define the basic principles of anatomy and identify the major levels of organization of human body with description of organ structure, size, localization inside the body in relation to adjacent structures,
- describe and recognize the major components of each organ system (muscular, skeletal, circulatory, respiratory, digestive, endocrine, renal, reproductive, integumentary),
- identify and describe the surface limits of the major body cavities (thorax, abdomen and pelvic cavity), including the detailed description of the limits of the mediastinum, pleural spaces, the four quadrants and nine descriptive regions of the abdomen in relation to underlying organs the relationship of the abdominal organs to the peritoneum (parietal and visceral layers) and the intestinal mesenteries,
- define the critical concept of human barrier (skin, respiratory, digestive system, hepatic sinusoids, kidney filtration barrier),
- describe the basic principles of the development of embryo and fetus, and the relationship with congenital malformations,
- recognize common anatomical variants,
- identify and describe the differences between the male and female when considering reproductive and endocrine systems, including the different embryological development and the anatomical changes that occur during pregnancy,
- define the layering structure of anatomical regions, their projection on the skin and the relation to the major surface and bony landmarks in each body region (e.g. occipital protuberance, orbital ridge, nasal bones, mastoid process, cervical to sacrococcygeal vertebrae and associated joints, shoulder girdle and upper limb, sternal region, ribs and costal margin, pelvic girdle and lower limb).
Expected learning outcomes
At the end of the Course of Macroscopic Human Morphology, the student should be able to:
- identify the key concepts of the structure and function of human anatomy: systems organization, morphology of the corresponding organs (including external and internal features) and their position in the body cavities and spaces,
- demonstrate an understanding of a specific embryological event or sequence of events that leads to the development of a particular body region or system,
- demonstrate a knowledge and an understanding of structure and a basic understanding of the function, of the different organ systems,
- demonstrate an understanding of the body region and of the different organ systems (topographic anatomy),
- demonstrate the appropriate oral communication skills involved in peer teaching of anatomy,
- know the basic clinical skills required to approach clinical anatomy: this course provides students with skills to prepare for clinical or health-related careers.
Single course

This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.

Course syllabus and organization

Single session

Course syllabus
The first semester provides an in-depth knowledge of the anatomy of the upper/lower limbs and thorax, incorporating; gross anatomy, surface anatomy, medical imaging, and embryology.
It focuses on gross anatomy of the bones, joints and muscles, basic embryology (week I through week IV of human development, including development of the skull, spine and limbs).
Definition of the terms relative to the anatomical position: anterior/ventral, posterior/dorsal, superior, inferior, medial, median, lateral, proximal, distal, superficial, deep, prone, supine, palmar & plantar.
Description of the anatomical planes (axial/transverse/horizontal, sagittal/vertical plane and the coronal/frontal plane) and of the corresponding terms used to describe the movements.
Introduction to the major surface and bony landmarks in each body region (e.g. occipital protuberance, orbital ridge, nasal bones, mastoid process, cervical to sacrococcygeal vertebrae and associated joints, shoulder girdle and upper limb, sternal region, ribs and costal margin, pelvic girdle and lower limb).
Description of the skull (bones & foramina/canals) intracranial cavities (anterior, middle and posterior cranial fossa), orbit bones, nasal cavity and paranasal sinuses, external-middle-inner ear and petrous temporal bone.
Classifications of the major bones that make up the axial (the main curvatures and features of the vertebral column, individual vertebrae cervical, thoracic, lumbar, sacral and coccygeal) and intervertebral joints and appendicular skeleton and summarizing their main differences and also the differences between compact and cancellous bone.
The different types of joints (synovial, fibrous and cartilaginous) and their associated structures (cartilage, tendons, ligaments, bursa) in relation to movement and stability.
Description of the major muscle groups of the head, neck, thorax, abdomen, pelvis, upper limb and lower limb.
The second semester focuses on topographical/systemic gross anatomy of the head, neck and body cavities (thorax, abdomen, pelvis, the four quadrants and nine descriptive regions of the abdomen in relation to underlying organs), cross sectional anatomy and corresponding embryology (lectures on the development of the organs and functional systems precede gross anatomical presentations and include frequently occurring malformations). During this semester the students will be introduced to the normal structure (including anatomical variants) and development of the gastrointestinal system and to the morphological basis of the function of the following systems:
Gastrointestinal system
Description of the major features of the oral cavity including the teeth, tongue, soft and hard palate.
Description of the salivary glands (parotid, submandibular and sublingual).
Description of the structure of the oesophagus.
Description of the relationship of the abdominal organs to the peritoneum (parietal and visceral layers) and the mesenteries.
Description of the regions of the stomach.
Description of the major sphincters of the gastrointestinal system in relation to their associated structures (oesophageal sphincter, cardiac sphincter, pyloric sphincter, ileocaecal sphincter, hepato‐pancreatic sphincter, anal sphincters).
Description of the constituent parts of the small intestine (duodenum, jejunum and ileum) and the large intestine (caecum, ascending colon, transverse colon, descending colon, sigmoid colon, rectum and anus).
Description of the lobes and major ligaments of the liver, the anatomy of the gallbladder, the anatomy of the pancreas and its associated ducts, and their position relative to the intestines.
Respiratory system
Description of the joints and muscles of respiration (accessory and intercostal muscles and thoracic joints, i.e. components of the sternum, ribs and costal cartilage articulations) and examine their contribution to the mechanism of breathing.
Description of the major features of the external nose, the nasal cavity, the pharynx, the larynx and the trachea.
Description of the major features of the diaphragm, pleural layers and the lungs (lobes and fissures of the right and left lungs; bronchi, bronchioles, alveoli; surface landmarks).
Identify and describe the course and role of the phrenic nerve in maintaining normal breathing.
Urinary system
Description of the main differences between the male and female urinary systems.
Description of the position of the kidneys and adrenal glands in relation to adjacent structures.
Description of the external and internal structure of the kidney and the relationship to the associated structures.
Description of the position of the bladder relative to associated structures in males and females (including during pregnancy).
Reproductive system
Differences between the male and female reproductive systems (organs, glands, external genitalia and pelvic characteristics).
Description of the anatomy of the pelvic diaphragm and perineum and their relationship to the neurovascular structures that supply these regions in males and females.
Structure and composition of the breast.
Endocrine
Identify the major endocrine structures (hypothalamus, anterior and posterior lobes of the pituitary gland, pineal gland thyroid gland and parathyroid glands, thymus, adrenal gland, pancreas, gonads, skin, heart, kidneys, gastrointestinal tract).
Cardiovascular system
Description of the position of the heart in the mediastinum relative to the associated structures.
Description of the atrial and ventricular chambers of the heart (macroscopic and functional features), the specialized conduction network, and the fibrous and serous layers of the pericardium; structure and location of the valves of the heart.
Description of the origin, course and main branches of the left and right coronary arteries and describe their location relative to the heart and the general area of the heart that they supply.
Structure of arteries, veins and capillaries.
Description of the structures of the pulmonary and systematic circulation.
Description of the course and important relationships of the major arteries and veins of the trunk, with emphasis on the aorta, superior vena cava and inferior vena cava, their major branches and associated pulse points.
Description of the deep and superficial veins and outline the course of the main veins of the upper limb and lower limb.
Description of the blood supply and venous drainage of the brain and its association to the great vessels of the heart and neck.
Description of the hepatic portal‐venous system.
Lymphatic system
Description of the drainage of lymph throughout the body.
Description of the primary (bone marrow & thymus) and secondary lymphoid (lymph nodes, spleen, tonsils and appendix) organs and tissues of the lymphatic system.
The third semester takes place in the second academic year and it focuses on central and peripheral nervous system, organs of special senses and corresponding embryology.
Description of the general features of nervous tissue, the spinal cord and the brain stem.
Introduction to the fundamentals of neural development.
Fundamental concepts, organizational principles, structure, connectivity, and how these relate to function and behavior are considered, with a strong emphasis on the clinical application of "traditional" neuroanatomical knowledge.
The forebrain (cerebral hemispheres), the midbrain (amygdala, thalamus, hypothalamus, hippocampus, pituitary gland, pineal gland and crus cerebri), the brainstem/hindbrain (pons, medulla oblongata and cerebellum).
Characteristics of the grey matter (e.g. nuclei, ganglia, cerebellar and cerebral cortex and basal nuclei/ganglia) and white matter (association, commissural and projection fibers, and the corpus callosum).
Cortical topography: frontal, parietal, temporal and occipital lobes and the major sulci/landmarks that separate them. Description of the cerebral cortex in relation to its functions, namely: motor, sensory, visual, auditory, speech; memory and emotion, decision making, social behavior.
Describe the organization of the internal capsule.
Basal ganglia (the caudate nucleus, putamen, and globus pallidus, their relationship with each other and with the lateral ventricle and internal capsule).
Description of the cerebellar anatomy (anatomic division and evolutionary terms neocerebellum, paleocerebellum and pontocerebellum).
Description of the cerebellar cortex and nuclei, afferents, internal circuitry, efferents and blood supply.
Identify the major structures of the limbic system (limbic lobe, hypothalamus, hippocampus, amygdala.
Describe and identify the anatomic features of the hypothalamus, the efferent connections of the hypothalamus with the autonomic nervous system and compare neuroendocrine secretion and control in the anterior and posterior pituitary.
Description of the structure of the spinal cord, a typical spinal nerve and a reflex arc, and its relation to the vertebral column.
Spinal and dorsal column-medial lemnisci, trigeminal lemniscus (proprioception i.e., joint position, tactile discrimination, vibration sense and form recognition).
Motor tracts: pyramidal [the corticobulbar and corticospinal tracts) and extrapyramidal (i.e., reticulospinal, vestibulospinal, tectospinal, rubrospinal including the basal ganglia (caudate, putamen, and globus pallidus), and the subthalamic nucleus].
Description of the 12 cranial nerves and their major functions in relation to innervation.
Description of the general organization of the outer, middle and inner ear.
Description of the structure of the visual system: eye, eyelid, conjunctiva and lacrimal gland.
Particular importance is given to central nervous pathways and to the anatomical basis of the reflexes (Moro reflex, abdominal reflexes, myotatic, tendon and those involving cranial nerves like as pupillary light reflex, the lacrimal reflex , the cough reflex, sucking and swallowing reflexes, the gag reflex, salivation, accommodation and corneal reflexes, vestibulo-ocular reflex, baroreflex) that are critical for clinical diagnosis and also for the basic understanding of the principles of motor control.
Description of the structural differences between the three layers of meninges (dura, arachnoid and pia), their relationship to the brain and spinal cord and the ventricular system and the formation, circulation, drainage and role of cerebrospinal fluid.
Prerequisites for admission
Students must have got a basic knowledge of Cytology, Histology and Cellular Biology.
Preparatory activities: in order to take the Macroscopic Human Morphology exam, the student must have passed the Microscopic and Ultrastructural Human Morphology exam.
Teaching methods
The course of anatomy takes place in a 6-year-degree course and it is organized in three semesters. Two semesters take place in the first academic year, the third in the second academic year.
- Lectures on concepts, anatomical organization, surface anatomy, sectional anatomy, variations. Lectures focus on a general introduction to anatomy and its terminology. A mixed topographical-systemic anatomy approach is applied to the limbs, head and neck, and to the organs of the thorax, abdomen, pelvis, and perineum (respiratory, endocrine, circulatory, gastrointestinal, and urogenital systems). Neuroanatomy is a fully developed unit.
- Use of plastic models in the anatomy class to show internal organ relationships and to allow students to repeatedly study a specimen. During these the students work in peer groups and are supported by the Anatomy teacher and by peer teaching or near-peer teaching assistants (i.e., medical students who have already passed the anatomy program, and are still in their medical school training). Although plastic models associated to low fidelity, they teach three-dimensional comprehension and anatomical reasoning, by showing the spatial relationship of the structures, which strongly correspond to the human body.
- Video acquisitions during classic or laparoscopic surgery have been introduced to underline anatomical concepts and to transpose them into a clinical setting. Each video is followed by a discussion with the students involving surgeons, endoscopists and anatomy teacher.
- During the course, groups of students (five to eight students) are solicited to elaborate under anatomy teacher supervision a presentation on an anatomical topic relevant to lecture content and derived from an article featured in scientific literature, focused around both clinical and scientific problems and to present them as lecture to the rest of the class (i.e., power point presentation). Anatomy teacher supervised the elaboration of students' lectures, in order to provide an appropriate guidance and motivation to students on how to improve their performance (quality of the report, level and fluency of oral presentation and ability to carry out literature search).
- We have started a pilot study with a selected group of first and second-year medical students where they learn to explore and create 3D visceral organ reconstruction alongside various CT cross-sectional slices of the neck, thorax and abdomen to describe patient specific anatomy. Moreover, they could have access to modules of macroscopic morphology (heart, lung, liver, kidney) based on Artificial Intelligence. During this pilot study, the students: 1) apply their basic anatomy knowledge to identify anatomical structures in the radiological image; 2) learn to use open-source software for imaging elaboration. Lastly, 3D scenes will be loaded in a Immersive Virtual Reality setting on an App that we have developed using head-mounted displays with tracker and coupled with a Smartphone.
Teaching Resources
- Gray's Anatomy - 41st Edition - ElsevierHealth.com‎ 2022
- Trattato di Anatomia Umana e Anatomia Topografica - Anatomy Bag e Risorse Digitali su Piattaforma Virtual Campus di Anastasi et al, Ed 2022
- The Developing Human 13° Edition Keith L. Moore, T. V. Persaud, Mark G. Torchia
- Neuroanatomy in Clinical Context: An Atlas of Structures, Sections, Systems, and Syndromes (Neuroanatomy: An Atlas of Structures, Sections, and Systems (English Edition) Duane E. Haines, Italian Edition by Maurizio Vertemati
- Fitzgerald's Clinical Neuroanatomy and Neuroscience (9th Ed) Estomih Mtui, Gregory Gruener, M. J. T. FitzGerald, Peter Dockery
- Netter Atlas of Human Anatomy X Ed, di Netter F.H.
Assessment methods and Criteria
The final exam (oral) is held at the end of the Macroscopic Human Morphology Course which takes place in three semesters: first and second semester of the first year and first semester of the second year.
To pass the exam, which validates the acquisition of the credits attributed to the Course, the following tests must be passed:
- Preliminary written test, preparatory to admission to the oral test: it consists of answering a set of multiple-choice quizzes relating to the entire exam program (except for students who have passed the ongoing test on the Locomotor System described below), distributed among the various topics in proportion to their relevance. For this test 40 quizzes are provided, each comprising five answers that can be true or false independently of each other. The correction is carried out automatically, by optical reading of a form filled in by the candidates.
Passing the quiz test allows, in the same session and only in that one, access to the oral exam. If the oral exam is not passed, the student must take the quiz test again, even in the case of sessions with more than one exam.
The test lasts 90 minutes.
The test is considered passed when the condition is satisfied:
t = 5 * N - e ≥ 46 where:
- N = number of quizzes in which all five questions were answered correctly
- e = number of incorrect questions.

N= 14 15 16 17 18 19 20
e≤ 20 25 30 35 40 45 50

- Oral exam: it consists of an interview on the topics of the entire program, namely Locomotor ((except for students who have passed the relevant ongoing test as described below)), Splanchnology, Neuroanatomy, Embryology, Systematics of blood and lymphatic circulation and Topographic Anatomy (except students who have passed the relevant ongoing test as described below).
The oral exam must be carried out within the same exam session in which the preliminary quiz test is taken.

If the student who has passed the ongoing tests relating to the Locomotor System and/or Systematics of Blood and Lymphatic Circulation and Topographical Anatomy does not pass the oral exam, the value of the tests will lapse. Therefore, in successful exam sessions, the student will have to take the preliminary quiz test on all the topics of the teaching program before trying again the oral test.

There are two optional ongoing tests relating to the following topics:
1) Locomotor system (General information, bones, joints and muscles);
2) Systematics of blood and lymphatic circulation (origin, course, main relationships and possible landmarks, distribution territory) and Topographic Anatomy.
Both tests consist of a quiz of 40 questions, each of which includes five answers, which can be true or false independently of each other.
Both tests will be considered passed when the following condition is satisfied:
t = 5 * N - e ≥ 46 where:
- N = number of quizzes in which all five questions were answered correctly
- e = number of incorrect questions.

N= 14 15 16 17 18 19 20
e≤ 20 25 30 35 40 45 50

Both tests last 60 minutes.
Passing the tests allows the exemption of the part concerning the arguments of Locomotor System, Systematics of Blood and Lymphatic Circulation and Topographical Anatomy from the preliminary quiz test and from the oral exam.
The validity of this ongoing test is for all exam sessions (7) subsequent to the end of the Course and relative to the current academic year.
BIO/16 - HUMAN ANATOMY - University credits: 12
Informal teaching: 32 hours
Lessons: 120 hours
Shifts: