Histology
A.Y. 2024/2025
Learning objectives
The course addresses cell morphology and ultrastructure, tissue organization of human cells and tissues, as well as the main methods and the instruments for their morphological analysis. Morphological and structural aspects of cell and tissues are described and discussed in relation to their functional role.
The core of knowledge acquired during this course is fundamental to understand the human anatomy, and functions and pathologies of the different organs and systems.
At the end of the course the student should be able to:
· Describe and identify tissues and cell ultrastructure
· Possess sufficient knowledge to proficiently attend the subsequent courses.
The core of knowledge acquired during this course is fundamental to understand the human anatomy, and functions and pathologies of the different organs and systems.
At the end of the course the student should be able to:
· Describe and identify tissues and cell ultrastructure
· Possess sufficient knowledge to proficiently attend the subsequent courses.
Expected learning outcomes
Recognize and describe eukariotic cells and their ultrastructure, the structure of human tissues and their localization in the human body, and the functional aspects in relation to the morphological organization.
Describe the mechanisms responsible for gametogenesis, fertilization, and the early stages of embryonic development, and the key characteristics of embryo annexes.
Describe the mechanisms responsible for gametogenesis, fertilization, and the early stages of embryonic development, and the key characteristics of embryo annexes.
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Linea Policlinico
Course syllabus
CYTOLOGY and HISTOLOGY:
Introduction to histology. Instruments and methods for samples preparation and observation at the microscope.
Cell membrane and inner cell compartments (endoplasmic reticulum, Golgi apparatus), ribosomes.
Vesicle trafficking. Exocytosis and endocytosis. Lysosomes. Peroxisomes.
Mitochondria.
Cytoskeleton.
Nucleus, nucleolus, cell cycle.
Epithelia: apical and basolateral specializations of epithelial cells. Cell junctions.
Lining epithelia: classification and localizations.
Exocrine glands.
Endocrine glands.
Connective tissue: cellular components and extracellular matrix.
Connective tissue: proper connective tissue. Adipose tissue.
Cartilage.
Bone and osteogenesis.
Blood and hemopoiesis.
Muscle tissue: skeletal, cardiac and smooth muscle tissues.
Nervous tissue
Dental tissues.
EMBRYOLOGY:
Male gametogenesis. Testes and cycle of the seminiferous epithelium. Introduction to genital ducts.
Female gametogenesis. Ovary and uterus. Maturation of follicles and menstrual cycle.
Fertilization. Early stages of the embryo development. Segmentation. Morula. Blastocyst implantation.
1st, 2nd and 3rd week of embryo development.
Embryo annexes.
Introduction to histology. Instruments and methods for samples preparation and observation at the microscope.
Cell membrane and inner cell compartments (endoplasmic reticulum, Golgi apparatus), ribosomes.
Vesicle trafficking. Exocytosis and endocytosis. Lysosomes. Peroxisomes.
Mitochondria.
Cytoskeleton.
Nucleus, nucleolus, cell cycle.
Epithelia: apical and basolateral specializations of epithelial cells. Cell junctions.
Lining epithelia: classification and localizations.
Exocrine glands.
Endocrine glands.
Connective tissue: cellular components and extracellular matrix.
Connective tissue: proper connective tissue. Adipose tissue.
Cartilage.
Bone and osteogenesis.
Blood and hemopoiesis.
Muscle tissue: skeletal, cardiac and smooth muscle tissues.
Nervous tissue
Dental tissues.
EMBRYOLOGY:
Male gametogenesis. Testes and cycle of the seminiferous epithelium. Introduction to genital ducts.
Female gametogenesis. Ovary and uterus. Maturation of follicles and menstrual cycle.
Fertilization. Early stages of the embryo development. Segmentation. Morula. Blastocyst implantation.
1st, 2nd and 3rd week of embryo development.
Embryo annexes.
Prerequisites for admission
There are no specific pre-requirements for the Histology and Embryology course
Teaching methods
Teaching methods (all compulsory):
· Lectures
· Asinchronous lectures
· Innovative teaching
· Tutorial activities using virtual slides and at the light microscope
Attendance required.
· Lectures
· Asinchronous lectures
· Innovative teaching
· Tutorial activities using virtual slides and at the light microscope
Attendance required.
Teaching Resources
Istologia
Adamo et al. Istologia di Monesi - Piccin.
Ross, Pawlina. Istologia: testo e atlante - Casa Editrice Ambrosiana.
Embriologia
Barbieri, Carinci. Embriologia - Casa Editrice Ambrosiana.
De Felici et al. Embriologia umana - Piccin.
Sadler - Embriologia Medica di Langman - Edra
Embriologia Umana (Larsen) - Edra
Atlanti
Gagliano. Eserciziario di Istologia - Piccin.
Gagliano. Colorare l'istologia - Piccin.
Wheater. Istologia e anatomia microscopica - Edra.
Ross, Pawlina, Barnash. Atlante di istologia e anatomia microscopica - Casa Editrice Ambrosiana.
Altri supporti didattici
Gagliano. QuickReviews Istologia - Edises.
Adamo et al. Istologia di Monesi - Piccin.
Ross, Pawlina. Istologia: testo e atlante - Casa Editrice Ambrosiana.
Embriologia
Barbieri, Carinci. Embriologia - Casa Editrice Ambrosiana.
De Felici et al. Embriologia umana - Piccin.
Sadler - Embriologia Medica di Langman - Edra
Embriologia Umana (Larsen) - Edra
Atlanti
Gagliano. Eserciziario di Istologia - Piccin.
Gagliano. Colorare l'istologia - Piccin.
Wheater. Istologia e anatomia microscopica - Edra.
Ross, Pawlina, Barnash. Atlante di istologia e anatomia microscopica - Casa Editrice Ambrosiana.
Altri supporti didattici
Gagliano. QuickReviews Istologia - Edises.
Assessment methods and Criteria
-The assessment method is based on an oral exam. The oral exam consists in the observation, description and identification of cells and histological samples on micrographs at the light and electron microscope, and in a discussion on the topics included in the course program.
- The correct identification of the histological sample is mandatory to complete the exam with the discussion on the topics included in the course program.
- Assessment parameters: the knowledge of cytology-histology and embryology, the ability to recognize and describe tissues based on the specific microscopic characteristics, and the efficacious communication of the information and with the appropriate terms will be assessed.
- Assessment: final mark (/30);
-The exam is deemed to be passed successfully if the final grade is equal to or higher than 18/30.
Registration to exams through SIFA is mandatory for each session.
- The correct identification of the histological sample is mandatory to complete the exam with the discussion on the topics included in the course program.
- Assessment parameters: the knowledge of cytology-histology and embryology, the ability to recognize and describe tissues based on the specific microscopic characteristics, and the efficacious communication of the information and with the appropriate terms will be assessed.
- Assessment: final mark (/30);
-The exam is deemed to be passed successfully if the final grade is equal to or higher than 18/30.
Registration to exams through SIFA is mandatory for each session.
BIO/17 - HISTOLOGY - University credits: 7
Informal teaching: 16 hours
Lessons: 60 hours
: 12 hours
Lessons: 60 hours
: 12 hours
Professors:
Gagliano Nicoletta, Sartori Patrizia Mirella
Shifts:
Gruppo 1
Professor:
Gagliano NicolettaGruppo 2
Professor:
Gagliano NicolettaGruppo 3
Professor:
Sartori Patrizia MirellaGruppo 4
Professor:
Sartori Patrizia MirellaTurno
Professor:
Gagliano NicolettaLinea San Donato
Course syllabus
CYTOLOGY and HISTOLOGY:
Introduction to histology. Instruments and methods for samples preparation and observation at the microscope.
Cell membrane and inner cell compartments (endoplasmic reticulum, Golgi apparatus), ribosomes.
Vesicle trafficking. Exocytosis and endocytosis. Lysosomes. Peroxisomes.
Mitochondria.
Cytoskeleton.
Nucleus, nucleolus, cell cycle.
Epithelia: apical and basolateral specializations of epithelial cells. Cell junctions.
Lining epithelia: classification and localizations.
Exocrine glands.
Endocrine glands.
Connective tissue: cellular components and extracellular matrix.
Connective tissue: proper connective tissue. Adipose tissue.
Cartilage.
Bone and osteogenesis.
Blood and hemopoiesis.
Muscle tissue: skeletal, cardiac and smooth muscle tissues.
Nervous tissue
Dental tissues.
EMBRYOLOGY:
Male gametogenesis. Testes and cycle of the seminiferous epithelium. Introduction to genital ducts.
Female gametogenesis. Ovary and uterus. Maturation of follicles and menstrual cycle.
Fertilization. Early stages of the embryo development. Segmentation. Morula. Blastocyst implantation.
1st, 2nd and 3rd week of embryo development.
Embryo annexes.
Introduction to histology. Instruments and methods for samples preparation and observation at the microscope.
Cell membrane and inner cell compartments (endoplasmic reticulum, Golgi apparatus), ribosomes.
Vesicle trafficking. Exocytosis and endocytosis. Lysosomes. Peroxisomes.
Mitochondria.
Cytoskeleton.
Nucleus, nucleolus, cell cycle.
Epithelia: apical and basolateral specializations of epithelial cells. Cell junctions.
Lining epithelia: classification and localizations.
Exocrine glands.
Endocrine glands.
Connective tissue: cellular components and extracellular matrix.
Connective tissue: proper connective tissue. Adipose tissue.
Cartilage.
Bone and osteogenesis.
Blood and hemopoiesis.
Muscle tissue: skeletal, cardiac and smooth muscle tissues.
Nervous tissue
Dental tissues.
EMBRYOLOGY:
Male gametogenesis. Testes and cycle of the seminiferous epithelium. Introduction to genital ducts.
Female gametogenesis. Ovary and uterus. Maturation of follicles and menstrual cycle.
Fertilization. Early stages of the embryo development. Segmentation. Morula. Blastocyst implantation.
1st, 2nd and 3rd week of embryo development.
Embryo annexes.
Prerequisites for admission
There are no specific pre-requirements for the Histology and Embryology course.
Teaching methods
Teaching methods (all compulsory):
· Lectures
· Asinchronous lectures
· Innovative teaching
· Tutorial activities using virtual slides and at the light microscope
Attendance required.
· Lectures
· Asinchronous lectures
· Innovative teaching
· Tutorial activities using virtual slides and at the light microscope
Attendance required.
Teaching Resources
Istologia
Adamo et al. Istologia di Monesi - Piccin.
Ross, Pawlina. Istologia: testo e atlante - Casa Editrice Ambrosiana.
Embriologia
Barbieri, Carinci. Embriologia - Casa Editrice Ambrosiana.
De Felici et al. Embriologia umana - Piccin.
Sadler - Embriologia Medica di Langman - Edra
Embriologia Umana (Larsen) - Edra
Atlanti
Gagliano. Eserciziario di Istologia - Piccin.
Gagliano. Colorare l'istologia - Piccin.
Wheater. Istologia e anatomia microscopica - Edra.
Ross, Pawlina, Barnash. Atlante di istologia e anatomia microscopica - Casa Editrice Ambrosiana.
Altri supporti didattici
Gagliano. QuickReviews Istologia - Edises.
Adamo et al. Istologia di Monesi - Piccin.
Ross, Pawlina. Istologia: testo e atlante - Casa Editrice Ambrosiana.
Embriologia
Barbieri, Carinci. Embriologia - Casa Editrice Ambrosiana.
De Felici et al. Embriologia umana - Piccin.
Sadler - Embriologia Medica di Langman - Edra
Embriologia Umana (Larsen) - Edra
Atlanti
Gagliano. Eserciziario di Istologia - Piccin.
Gagliano. Colorare l'istologia - Piccin.
Wheater. Istologia e anatomia microscopica - Edra.
Ross, Pawlina, Barnash. Atlante di istologia e anatomia microscopica - Casa Editrice Ambrosiana.
Altri supporti didattici
Gagliano. QuickReviews Istologia - Edises.
Assessment methods and Criteria
-The assessment method is based on an oral exam. The oral exam consists in the observation, description and identification of cells and histological samples on micrographs at the light and electron microscope, and in a discussion on the topics included in the course program.
- The correct identification of the histological sample is mandatory to complete the exam with the discussion on the topics included in the course program.
- Assessment parameters: the knowledge of cytology-histology and embryology, the ability to recognize and describe tissues based on the specific microscopic characteristics, and the efficacious communication of the information and with the appropriate terms will be assessed.
- Assessment: final mark (/30);
-The exam is deemed to be passed successfully if the final grade is equal to or higher than 18/30.
Registration to exams through SIFA is mandatory for each session.
- The correct identification of the histological sample is mandatory to complete the exam with the discussion on the topics included in the course program.
- Assessment parameters: the knowledge of cytology-histology and embryology, the ability to recognize and describe tissues based on the specific microscopic characteristics, and the efficacious communication of the information and with the appropriate terms will be assessed.
- Assessment: final mark (/30);
-The exam is deemed to be passed successfully if the final grade is equal to or higher than 18/30.
Registration to exams through SIFA is mandatory for each session.
BIO/17 - HISTOLOGY - University credits: 7
Informal teaching: 16 hours
Lessons: 60 hours
: 12 hours
Lessons: 60 hours
: 12 hours
Professors:
Bianchi Francesca, Gagliano Nicoletta
Shifts: