The Effect of Endocrine Disruptors On Health

A.Y. 2024/2025
4
Max ECTS
32
Overall hours
SSD
MED/13
Language
Italian
Learning objectives
The upcoming course will give an overview on the fundamental notions on endocrine disruptors and the effects they can have on human health. It is possible to find these substances in everyday necessities and in food with the ability to interfere with normal hormonal activity by inducing abnormal reactions. The course aims to provide the basics of the different mechanisms of action of endocrine disruptors. The effects of these interferents on the functionality of the endocrine glands (i.e., metabolism, reproduction) and the nervous system (i.e., behavior) will be discussed. These aspects will be discussed on various stages of life and possible sexual differences. It will be possible to understand endocrine disruptors and the possible risks associated with their exposure.
Expected learning outcomes
At the end of the course the students are expected to demonstrate the knowledge of the mechanisms and effects exerted by endocrine disruptors on all phases of hormones such as synthesis, action and degradation from a molecular point of view and considering the different organs.
Single course

This course can be attended as a single course.

Course syllabus and organization

Single session

Responsible
Lesson period
First semester
Course syllabus
The program includes:

- Introduction to the course
- QUIZ: How much are you exposed to the Endocrine Disrupting Chemicals (EDC)?
- Concepts of environmental endocrinology
- How the concept of EDC was born
- Knowledge of the past and the challenges of the future
- IE origin, classification and mechanisms of action
- IE and exposure
- IE and male fertility
- IE and female fertility
- Epigenetics and transgenerational effects
- IE and thyroid
- EI and diet (obesogenic)
- IE and gut microbiota
- EI and neurodevelopmental disorders
Prerequisites for admission
Fundamental knowledge in human anatomy and biology
Teaching methods
Frontal lessons
Teaching Resources
Materials provided by the teacher (slides and scientific articles)
Assessment methods and Criteria
PowerPoint presentation of an original article suggested by the professor related to a topic of the course
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 4
Lessons: 32 hours
Professor: Diviccaro Silvia