Drugs and Innovation
A.Y. 2024/2025
Learning objectives
The course is aimed at showing and discussing the most recent innovations in the context of the development and of the use of drugs. It will cover the need to implement the knowledge on innovative therapies and their use, especially in special populations such as kids, pregnant women, and elderly. It will also discuss the important role of implementing personalized therapies in medicine. In this context it will discuss how a better knowledge and investigation of the genome can be used in the prediction of the diagnosis, of the treatment response and of the development of side effects.
Expected learning outcomes
Better knowledge of the definition of special populations and how pharmacology has to adapt according to the clinical and medical features of the patient. Knowledge of the definition of precision medicine and of the techniques and of the prediction models that can be used to implement precision medicine in different pathologies. Knowledge of the existing limitations in the development and use of personalized therapies. Ability to critically analyze data in scientific literature on examples related to pharmacology in special population and related to personalized medicine.
Lesson period: year
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
Single session
Responsible
Lesson period
year
Prerequisites for admission
Basic Knowledge in Pharmacology, Biochemistry and physiopathology.
Assessment methods and Criteria
The exam will be an oral representation and discussion of a scientific paper that will be provided during the course
Pharmacology and special populations
Course syllabus
Definition of special populations (elderly, populations with impaired metabolism system, pregnant and/or lactating women, children, ethnic subgroups)
Clinical pharmacology in the critically ill patient
Clinical pharmacology in oncohaematological and/or transplant patients
Clinical pharmacology in obese patients or patients with impaired drug metabolism system
Pharmacology during pregnancy and lactation
Medications in children
Medications in the elderly
Clinical pharmacology in the critically ill patient
Clinical pharmacology in oncohaematological and/or transplant patients
Clinical pharmacology in obese patients or patients with impaired drug metabolism system
Pharmacology during pregnancy and lactation
Medications in children
Medications in the elderly
Teaching methods
The course includes frontal lessons (2 hours each), during which the proposed subjects will be explained and examined in depth via recent scientific manuscripts. Lessons will be devoted to databases for clinical trials and for artificial intelligences where also practical examples will be given. Different innovative methodological tools will be used.
Teaching Resources
Teaching material will be made available on the web site Ariel
Personalized pharmacological Therapy
Course syllabus
Definition of precision medicine
Role of the genome and omics techniques
Pharmacogenetics and pharmacogenomics
Prediction patterns for diagnosis, response to treatment and appearance of side effects
Examples of medical conditions in which precision medicine is used
Psychiatry and precision medicine
Cardiovascular disorders and precision medicine
Cancer and precision medicine
Diabetes and precision medicine
Migraine and precision medicine
Limits of precision medicine
Role of the genome and omics techniques
Pharmacogenetics and pharmacogenomics
Prediction patterns for diagnosis, response to treatment and appearance of side effects
Examples of medical conditions in which precision medicine is used
Psychiatry and precision medicine
Cardiovascular disorders and precision medicine
Cancer and precision medicine
Diabetes and precision medicine
Migraine and precision medicine
Limits of precision medicine
Teaching methods
The course includes frontal lessons (2 hours each), during which the proposed subjects will be explained and examined in depth via recent scientific manuscripts. Lessons will be devoted to databases for clinical trials and for artificial intelligences where also practical examples will be given. Different innovative methodological tools will be used.
Teaching Resources
Teaching material will be made available on the web site Ariel
Personalized pharmacological Therapy
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 32 hours
Professor:
Cattaneo Annamaria
Pharmacology and special populations
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 32 hours
Professor:
Cattaneo Annamaria
Professor(s)