Analytical Methods in Drug Discovery and Development and Validation of Analytical Procedures in Pharmaceutical Industry

The main objective of the course is to illustrate and discuss the most important analytical approaches used in the different stages of the process of research, development and production of drugs. In particular, the course involves the transfer of knowledge of the most modern analytical approaches used in the research and development process and in particular: a) to identify and validate the therapeutic targets; b) to define the mechanism of action of the molecules identified with phenotypic approaches; c) to identify the target compounds; d) to characterize the molecular interactions ligand-target; e) to identify and optimize the lead compounds. The course also includes training on the analytical aspects used in industry for the processes development not only of small molecules but also of large molecules and phyto-derived products.
In line with its concept of professionalizing course, the course aims therefore not only to transfer to the student the most modern knowledge in pharmaceutical analysis, but also to provide the tools needed to develop a critical approach necessary to address the analytical issues in the field of research, development and production of the drug.

At the end of the learning process the student must know the most important analytical applications used in the processes of research, development and production of the drug. The student must also understand the main analytical problems and design possible solutions applying not only the knowledge acquired during the course but also that obtained in the modules of advanced methodologies in pharmaceutical chemistry.