Advances in Drug Delivery Systems (modules I and II)
A.Y. 2024/2025
Learning objectives
The course aims to deepen the principles behind formulation/design, preparation/production and control of the main forms of conventional dosage and modified release.
In addition, this objective is sought by means of student participation in practical laboratory exercises.
In addition, this objective is sought by means of student participation in practical laboratory exercises.
Expected learning outcomes
At the end of the course the student must have a thorough knowledge of the various types of dosage forms and be able to propose formulation strategies for the development of specific products.
Lesson period: Second semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
Single session
Responsible
Lesson period
Second semester
Prerequisites for admission
The knowledge of technological operations for the preparation of oral solid pharmaceutical forms and basic knowledge of biopharmaceuticals are useful for a fruitful use of the course.
Assessment methods and Criteria
The exam of the course is oral and includes a lecture of a research topic chosen by the student. The topic is related to what was taught in class. The lecture is followed by a discussion
Advances in Drug Delivery Systems Mod. I
Course syllabus
The program of the lectures includes an in-depth study of topics regarding oral administration through orodispersible pharmaceutical forms. Furthermore, the technologies based on the administration of active ingredients through microneedles are addressed. Finally, the problems related to the delivery of genetic material through non-viral nanovectors are addressed.
The exercises, in analogy with the topics covered in the lectures, concern:
- the formulation, preparation and characterization of orodispersible films containing microparticles for the prolonged release of active ingredients
- the design through the creation of a cad file, the production through 3D printing by photopolymerization and the characterization of microneedles.
The exercises, in analogy with the topics covered in the lectures, concern:
- the formulation, preparation and characterization of orodispersible films containing microparticles for the prolonged release of active ingredients
- the design through the creation of a cad file, the production through 3D printing by photopolymerization and the characterization of microneedles.
Teaching methods
The lessons, integrated with exercises, are organized so that the student can acquire skills in the creation of innovative pharmaceutical forms and in the statistical re-elaboration of the characterization results obtained.
Teaching Resources
1. Slides of the lessons provided by the teacher or downloadable from the ARIEL website
2. P. Colombo, P.L. Catellani, A. Gazzaniga et al., Principi e Tecnologie Farmaceutiche, CEA, Milano (2007).
2. P. Colombo, P.L. Catellani, A. Gazzaniga et al., Principi e Tecnologie Farmaceutiche, CEA, Milano (2007).
Advances in Drug Delivery Systems Mod. II
Course syllabus
The class lessons program includes:
- innovative oral solid pharmaceutical forms
- Quality by Design paradigm for pharmaceutical production
- oral delayed-release systems
For the laboratory lessons part:
- characterization of powders for pharmaceutical use
- mixing of powders
- preparation of tablets
- coating of solid pharmaceutical forms
- preparation of multiparticulate forms
- physical-technological characterization of oral solid pharmaceutical forms
- innovative oral solid pharmaceutical forms
- Quality by Design paradigm for pharmaceutical production
- oral delayed-release systems
For the laboratory lessons part:
- characterization of powders for pharmaceutical use
- mixing of powders
- preparation of tablets
- coating of solid pharmaceutical forms
- preparation of multiparticulate forms
- physical-technological characterization of oral solid pharmaceutical forms
Teaching methods
The lessons include a theoretical study of the knowledge acquired in previous Pharmaceutical Technology courses and the putting into practice of different processes and methodologies
Teaching Resources
1. Slides of the lessons provided by the teacher or downloadable from the ARIEL website
2. P. Colombo, P.L. Catellani, A. Gazzaniga et al., Principi e Tecnologie Farmaceutiche, CEA, Milano (2007).
2. P. Colombo, P.L. Catellani, A. Gazzaniga et al., Principi e Tecnologie Farmaceutiche, CEA, Milano (2007).
Advances in Drug Delivery Systems Mod. I
CHIM/09 - PHARMACEUTICAL AND TECHNOLOGICAL APPLICATIONS OF CHEMISTRY - University credits: 4
Single bench laboratory practical: 32 hours
Lessons: 16 hours
Lessons: 16 hours
Professors:
Cilurzo Francesco, Melocchi Alice
Advances in Drug Delivery Systems Mod. II
CHIM/09 - PHARMACEUTICAL AND TECHNOLOGICAL APPLICATIONS OF CHEMISTRY - University credits: 4
Single bench laboratory practical: 32 hours
Lessons: 16 hours
Lessons: 16 hours
Professors:
Gazzaniga Andrea, Palugan Luca
Professor(s)
Reception:
by appointment
Via G. Colombo 71