System Diseases 2

The System Diseases 2 course takes the students into clinical medicine with the study of the "Blood Diseases" (Hematology) and the "Diseases of the Respiratory System" (Pneumology). Such studies will be dealt on a comprehensive basis, i.e. including Diagnostic Imaging, Pathology, Clinical Biochemistry and Microbiology, in relation to the diseases of the organ. The students will aquire knowledge on: -the basic concept of laboratory test which will be integrated with new methodologies to be translated in the near future in clinical laboratory: clinical enzymology, methodologies utilized to monitor proteins, antibodies and RNA messengers. -basic concepts related to new and high throughput technologies applied to biological fluids for markers monitoring. -the most important aspect of respiratory medicine, examining prevalence, risk factors, pathophysiological and clinical aspect of the most important lung diseases. - the analysis of the most relevant respiratory disease entities from pathogenesis to clinical features to diagnostic approach and principles of treatment. - the respiratory diseases during differential diagnosis in routine clinical practice, and perform/interpret the correct laboratory tests to exclude/confirm the diagnosis and for clinical management. -the most relevant hematological disease entities from pathogenesis to clinical features to diagnostic approach and principles of treatment. -the relevance of infectious diseases on the pathogenesis of hematological malignancies and during the various stages of cancer treatment - the imaging techniques and interpretation of radiologic studies. - the pathogenetic mechanisms, morphologic changes, evolution and complications of obstructive, restrictive diseases of the lung together with pulmonary infections and neoplastic diseases of lung and pleura.

Students are expected to achieve general and specific requirements: - report main diagnostics imaging modalities used to evaluate the respiratory system (X-ray, ultrasound, computed tomography [CT]). - describe the normal anatomy on a chest radiograph, the normal anatomy on a chest CT and how and when to perform a contrast-enhanced or non-contrast CT and understand when ultrasound should be used in the lung. -recognize the main abnormalities on a chest radiograph and the main abnormalities on a CT of the chest related to the main respiratory diseases -describe pathogenetic mechanisms, morphologic changes, evolution and complications of respiratpry and hematologic diseases. - recognize the pathogenesis, clinical features, diagnostic approach and principles of treatment of the most relevant respiratory disease entities. - Report indications, technique and complications of image-guided pulmonary interventional procedures. - Recognize the main features of imaging of thrombosis and pulmonary thromboembolism and related interventional procedures - intravascular thrombolysis, vena cava filters. - describe the basic concept of laboratory test. - describe the role of bone marrow biopsy in the diagnosis of myeloid neoplasms, their ontogenetic process and the updated classification -recognize the pathogenesis, clinical features, diagnostic approach and principles of treatment of the most relevant hematologic disease entities.