Organic Chemistry Ii
A.Y. 2022/2023
Learning objectives
The course is a continuation of Organic Chemistry I and aims at providing an introduction to the chemistry of carbocyclic aromatic compounds. Additional topics include the chemistry of heterocyclic aromatic compounds.
Expected learning outcomes
Skills acquired by the students at the end of the course are the knowledge of the chemistry of aromatic systems. In particular, they will achieve competences in the design of the synthesis of aromatic and heteroaromatic systems, even of pharmacological interest.
Lesson period: year
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Lesson period
year
Course syllabus
During theoretical classes, the concepts of aromaticity and antiaromaticity, and the fundamental structural characteristics of aromatic carbocyclic systems (benzene and derivatives) on which is based their reactivity are illustrated. Then, the main classes of reactions such as electrophilic and nucleophilic aromatic substitution, are presented, showing in details the mechanism and scope. The main classes of aromatic compounds are described. In particular, characteristics, reactivity and synthesis of arenes and alkylarenes, naphthalene, aryl and arylaliphatic arenes, nitrogen derivatives (nitro-, nitroso-, and azocompounds, arylhydroxylamines, mono- and diarylhydrazines, aromatic amines, diazonium salts), phenols and derivatives, aldehydes and ketones, nitriles, carboxylic acids and derivatives, sulfur compounds, quinones. In the second part of the course, the most important classes of heteroaromatic compounds are described, with their structural characteristics, reactivity and synthesis. In particular, pyrrole, furan, thiophene and their benzocondensed indole, benzofuran and benzothiophene are presented, some six-member atoms heterocyclic compounds such as pyridine, quinoline and isoquinoline are described. Finally, some selected information about five-member heterocycles containing two heteroatoms such as imidazole, pyrazole and isooxazole is given. The course is divided in three parts: after each part a set of interactive exercises related to the topic described are organized.
Prerequisites for admission
Basic knowledge of organic chemistry are required. Students must therefore have attended Organic Chemistry I course and acquired the related skills, that are necessary to understand Organic Chemistry II.
Teaching methods
Lessons will be held in classrooms (using blackboard whenever possible) as scheduled in the timetable.
Teaching Resources
The following books are recommended:
1] John D. Hepworth, David R. Waring and Michael J. Waring, Aromatic Chemistry, Royal Society of Chemistry, Cambridge, 2002
2] Brown, Foote, Iverson, Anslyn, CHIMICA ORGANICA, EdiSES, VI edition
3] Marc Loudon, CHIMICA ORGANICA, EdiSES
Students can communicate with the teacher through e-mail, or making an appointment
1] John D. Hepworth, David R. Waring and Michael J. Waring, Aromatic Chemistry, Royal Society of Chemistry, Cambridge, 2002
2] Brown, Foote, Iverson, Anslyn, CHIMICA ORGANICA, EdiSES, VI edition
3] Marc Loudon, CHIMICA ORGANICA, EdiSES
Students can communicate with the teacher through e-mail, or making an appointment
Assessment methods and Criteria
The exam includes a written and an oral test, both compulsory.
As regards the written test, in order to simplify the learning of the subject and to facilitate the verification of knowledge, two intermediate written tests will be organized, each at the end of the two parts of the course. The final marks will result from the average of the two marks. For admission to the oral test the student will have to achieve a pass grade (not less than 18/30) in both intermediate written tests. In case of negative grade achieved in one of the intermediate written tests, students will need to pass a written test focused on the whole course program to get admitted to the oral test.
The oral test will cover the entire program of the course.
As regards the written test, in order to simplify the learning of the subject and to facilitate the verification of knowledge, two intermediate written tests will be organized, each at the end of the two parts of the course. The final marks will result from the average of the two marks. For admission to the oral test the student will have to achieve a pass grade (not less than 18/30) in both intermediate written tests. In case of negative grade achieved in one of the intermediate written tests, students will need to pass a written test focused on the whole course program to get admitted to the oral test.
The oral test will cover the entire program of the course.
CHIM/06 - ORGANIC CHEMISTRY - University credits: 7
Practicals: 16 hours
Lessons: 48 hours
Lessons: 48 hours
Professor:
Lay Luigi
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