Toxicology 1

Aim of the course is to provide the fundamental knowledge to understand the basic principles of toxicology through:
- the scientific basis of experimental toxicology
- the characterisation of the mechanisms of toxicity of the main chemical pollutants in air, water, soil and drugs, including the factors modulating the incidence and severity of a toxic event
- the analysis of adverse manifestations of xenobiotics and drugs on organs
- the basics of the criteria for evaluating and extrapolating toxicity data to humans through technical, scientific and regulatory sources in the field of environmental and health safety

Knowledge and understanding of the general concepts and molecular basis of toxicology with particular reference to the general principles of toxicity and organ toxicity of xenobiotics and drugs and the factors that modulate the incidence and severity of a toxic event.
Knowledge of the principles underlying the approaches used at European level for hazard and risk assessment.