Technology-Driven Organic Synthesis

The course aims at presenting innovative and alternative organic synthetic methods, with low environmental impact, economically sustainable, based on the use of new technologies. The learning objectives of the course are the following:
- to introduce the students to the use of enabling technologies in organic chemistry to carry out alternative/innovative syntheses of pharmaceutical products and, in general, of fine chemicals.
- to present the general concepts of flow chemistry (advantages, equipment) and its applications, both at laboratory and industrial level, for the creation of unprecedented synthetic processes;
- to introduce the use of photocatalysis in organic synthesis for the formation of C-C and C-X bonds promoted by light. The advantages of carrying out photocatalysed reactions in continuous flow conditions will be highlighted through examples reported in the literature;
- to introduce the use of electrochemistry in organic synthesis, applied to the preparation of functionalized small molecules, presenting both the equipment and the new synthetic methodologies;
- to introduce the general concepts of artificial intelligence and machine learning applied to organic synthesis.

At the end of the course, the student is expected to:
- have acquired knowledge and understanding of the enabling technologies presented in the course and the advantages of their application in organic synthesis;
- have acquired competence and ability to discuss the enabling technologies applied to the synthesis of an organic compound;
- be able to propose a synthesis/transformation of a functionalized organic compound through the methods presented in the course;
- be able to independently carry out bibliographic research about the relevant scientific literature.