Polymorphism and Crystal Forms in Industry

The course is designed to provide students with a comprehensive understanding of the fundamental principles governing of solid-state chemistry of crystal forms. Key topics include polymorphic behavior, thermodynamics and kinetics of phase transitions, polymorphism, and crystallization techniques, equipping students with the necessary knowledge to tackle solid-state challenges in industrial applications.
Additionally, the course will introduce essential analytical techniques for solid-state characterization, covering X-ray powder diffraction (both laboratory scale and synchrotron radiation), X-ray fluorescence, thermal analyses, hot-stage microscopy, and advanced combined or in situ techniques. By the end of the course, students will develop the analytical skills required to independently address qualitative and quantitative solid-state problems of industrial relevance.

By the end of the course, students will be able to analyze and solve common qualitative and quantitative solid-state challenges relevant to industrial applications. They will gain the ability to describe and interpret phase transitions, polymorphic behavior, and crystallization processes, as well as to apply best practices for crystallization and solid-state optimization in the production of pharmaceuticals, pigments, and other industrially relevant materials.