Medicinal and Toxicological Chemistry I

The course aims to provide the student with:
a) the knowledge that underlies the design and development of new active ingredients having the necessary requisites to be able to become drug candidates;
b) a good knowledge of the properties, the mechanisms of action and the use of the different classes of drugs treated;
c) the fundamental knowledge on the structure-activity relationships for the purpose of a more rational design aimed at a therapeutic effect free from contraindications and toxic effects;
d) indications concerning the synthetic methods used for the preparation of some of the drugs considered.

The student must demonstrate to have acquired what is foreseen by the educational objectives.
In particular, the student must demonstrate that he / she has acquired and understood:
a) the basic concepts of Medicinal Chemistry and the fundamental elements of drug design;
b) the notions provided on the chemical, chemical-physical, structural properties and on the mechanism of action of the drugs belonging to the therapeutic classes considered and the main synthetic strategies that can be used for the preparation of drugs.