Infectious Diseases

A.Y. 2024/2025
5
Max ECTS
64
Overall hours
SSD
MED/17
Language
Italian
Learning objectives
At the end of the course the student will:
· have acquired the epidemiological, clinical-anamnestic and instrumental elements to identify the main infectious diseases
· have acquired the elements to evaluate the main laboratory investigations used for the diagnosis of infectious diseases
· have acquired the elements to identify the main infectious diseases
· know how to indicate the main classes of antibiotics and their use in bacterial infections
· know how to indicate the main classes of antivirals and antifungals
· be able to report the main measures of individual and general prophylaxis relating to infectious diseases
Expected learning outcomes
At the end of the course, the student has to:
· acquire the main knowledge related to epidemiology, etiology, pathogenesis, natural history, diagnostics and therapy principles of the main infectious diseases of the following organs and systems: respiratory, gastrointestinal, central nervous system as well as exanthematous diseases, systemic diseases and main tropical diseases
· know the individual and collective prophylaxis measures as well as the regulations in force relating to contumacy measures
· know the microbiological and instrumental investigations necessary to reach a correct diagnosis of infectious disease;
· be able to correctly interpret the information contained in the microbiological and instrumental reports in order to obtain precise indications for an adequate therapeutic decision-making process.
Single course

This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.

Course syllabus and organization

Linea Policlinico

Course syllabus
Exanthematous infections
Epidemiology
Etiology
Pathogenesis and clinic (typical course and complications)
Therapeutic possibilities
Active and passive prophylaxis
of the following exanthematous diseases: measles, rubella, infectious megaloerythema, critical exanthema, scarlet fever, varicella, and other vesicular exanthema

Infections of the respiratory system
Infectious syndromes of the respiratory system:
Diphtheria
Pharyngitis/tonsillitis
Epiglottitis/laryngitis/tracheitis
Acute bronchitis and flare-ups of chronic bronchitis
Bronchiolitis
Viral pneumonias
Bacterial pneumonias
Influenza
Pulmonary tuberculosis (and extrapulmonary forms)
Whooping cough

Liver and biliary tract infections
Epidemiology, etiology, and pathogenesis of viral hepatitis
Diagnosis of acute and chronic viral hepatitis
Therapy of viral hepatitis
Yellow fever
Leptospirosis
Hydatidosis
Biliary tract infections

Infections of the digestive tract: infectious diarrheas
Etiological and pathophysiological classification
Food poisoning (staphylococcal, botulism, C. perfrigens, V. parahaemoliticus, B. cereus)
Viral gastroenteritis (Norwalk, Rotavirus, other viruses involved)
Bacterial gastroenteritis (Cholera, E.coli, minor salmonellosis, Shigella, Campylobacter, C. difficile)
Protozoal diarrheas (giardiasis, amebiasis, cryptosporidiosis)
Helminth diarrheas (tapeworm, oxyuriasis, ascaridiasis)

Tropical Diseases
Epidemiology of tropical diseases: what are the 6 "deadly killers"?
Malaria
Epidemiology
Life cycle
Pathogenesis
Typical and atypical presentation
Complications and prognosis
Diagnosis
Differential diagnosis between plasmodia
Principles of therapy and prophylaxis
Schistosomiasis
Epidemiology
Life cycle
Clinical: acute form, chronic forms
Diagnosis
Therapy
Control measures

Arthropod-borne infections
Dengue
West-Nile fever
Zika virus
Chikungunya
Viral hemorrhagic fevers
Rickettsiosis exanthema and ehrlichiosis

Systemic infections
Infectious mononucleosis and CMV infection
Brucellosis
Cutaneous and visceral leishmaniasis
Lyme diseases
Toxoplasmosis
Atypical mycobacterioses

Sepsis and septic shock
Etiology and epidemiology
Pathophysiology and pathogenesis
Clinical framing
The microbiological diagnosis
The antibiotic and supportive therapeutic approach

HIV infection
History
Epidemiology
Life cycle of HIV
Natural history of infection
Immunopathogenesis
Main opportunistic manifestations, divided by systems
Diagnosis of acute and chronic infection
Infections of the immunocompromised host
Infections in the solid organ transplant patient
Infections in the patient with bone marrow transplantation
Infections in the patient with neoplasia
Infections in the splenectomized patient
Infections in the diabetic patient
Infections in the alcoholic patient
Infections in the injection drug patient

Infections of the soft tissues and musculoskeletal system
Cellulitis and soft tissue infections, particularly:
Erisipelas
Gas gangrene
Necrotizing fasciitis
Primitive septic arthritis and on media
Primary osteomyelitis and on synthetic media
Spondylodiscitis

Infections of the cardiovascular system
Infective endocarditis
Etiology
Clinical manifestations and complications
Diagnosis (Dukes' criteria)
Principles of therapy and prophylaxis
Infectious myocarditis and pericarditis
Clinical manifestations and complications
Principles of diagnosis

Urinary tract infections and sexually transmitted diseases
Cystitis
Pyelonephritis
Syphilis
Gonorrhea
Chlamydia and pelvic inflammatory disease (PID)
Trichomonas
Gardrenella
Lymphogranuloma venereum

Infections of the nervous system
Meningitis
Etiology
Pathogenesis
Clinical manifestations
Diagnosis (clinical and laboratory, with emphasis on CSF analysis)
Principles of therapy
Encephalitis and encephalomyelitis
General pathogenesis
Clinical manifestations
Diagnostic evaluation
Main etiologic agents and their clinical features
HSV and VZV
CMV
Enterovirus
rabies
Bacterial toxin-mediated neuraxitis
Brain abscess and subdural empyema
Prerequisites for admission
No prior knowledge is required
Teaching methods
Formal teaching (32 hours):
frontal didactics 24 hours
Innovative asynchronous didactics: 8 hours (dedicated to student study of articles uploaded to MyAriel and presented during frontal classroom teaching)

Non-formal didactics (16 hours):
clinical case presentations
Teaching Resources
"Malattie Infettive" di Moroni, Esposito, Antinori
"Principles and Practice of Infectious Diseases" Mandell, Douglas and Bennett's
Assessment methods and Criteria
Admission to the examination is subject to attending at least 66 percent of the classes.
The examination will include a written test (multiple-choice quizzes) and an oral test.

Multiple-choice quiz No. 30 questions in 30 minutes.
Evaluation to access the oral test 18/30
The result of the written test does not average with the final grade.

There are no scheduled:
Intermediate tests
Pre-appeals
Useful materials for taking the test

The results of the written test will be communicated to students in the classroom after the written exam has been corrected and before the oral exam begins.
MED/17 - INFECTIOUS DISEASES - University credits: 5
Informal teaching: 16 hours
Lessons: 48 hours
Shifts:
Gruppo 1
Professor: Gori Andrea
Gruppo 2
Professor: Bandera Alessandra
Turno
Professors: Bandera Alessandra, Gori Andrea

Linea San Donato

Course syllabus
Exanthematous infections
Epidemiology
Etiology
Pathogenesis and clinic (typical course and complications)
Therapeutic possibilities
Active and passive prophylaxis
of the following exanthematous diseases: measles, rubella, infectious megaloerythema, critical exanthema, scarlet fever, varicella, and other vesicular exanthema

Infections of the respiratory system
Infectious syndromes of the respiratory system:
Diphtheria
Pharyngitis/tonsillitis
Epiglottitis/laryngitis/tracheitis
Acute bronchitis and flare-ups of chronic bronchitis
Bronchiolitis
Viral pneumonias
Bacterial pneumonias
Influenza
Pulmonary tuberculosis (and extrapulmonary forms)
Whooping cough

Liver and biliary tract infections
Epidemiology, etiology, and pathogenesis of viral hepatitis
Diagnosis of acute and chronic viral hepatitis
Therapy of viral hepatitis
Yellow fever
Leptospirosis
Hydatidosis
Biliary tract infections

Infections of the digestive tract: infectious diarrheas
Etiological and pathophysiological classification
Food poisoning (staphylococcal, botulism, C. perfrigens, V. parahaemoliticus, B. cereus)
Viral gastroenteritis (Norwalk, Rotavirus, other viruses involved)
Bacterial gastroenteritis (Cholera, E.coli, minor salmonellosis, Shigella, Campylobacter, C. difficile)
Protozoal diarrheas (giardiasis, amebiasis, cryptosporidiosis)
Helminth diarrheas (tapeworm, oxyuriasis, ascaridiasis)

Tropical Diseases
Epidemiology of tropical diseases: what are the 6 "deadly killers"?
Malaria
Epidemiology
Life cycle
Pathogenesis
Typical and atypical presentation
Complications and prognosis
Diagnosis
Differential diagnosis between plasmodia
Principles of therapy and prophylaxis
Schistosomiasis
Epidemiology
Life cycle
Clinical: acute form, chronic forms
Diagnosis
Therapy
Control measures

Arthropod-borne infections
Dengue
West-Nile fever
Zika virus
Chikungunya
Viral hemorrhagic fevers
Rickettsiosis exanthema and ehrlichiosis

Systemic infections
Infectious mononucleosis and CMV infection
Brucellosis
Cutaneous and visceral leishmaniasis
Lyme diseases
Toxoplasmosis
Atypical mycobacterioses

Sepsis and septic shock
Etiology and epidemiology
Pathophysiology and pathogenesis
Clinical framing
The microbiological diagnosis
The antibiotic and supportive therapeutic approach

HIV infection
History
Epidemiology
Life cycle of HIV
Natural history of infection
Immunopathogenesis
Main opportunistic manifestations, divided by systems
Diagnosis of acute and chronic infection
Infections of the immunocompromised host
Infections in the solid organ transplant patient
Infections in the patient with bone marrow transplantation
Infections in the patient with neoplasia
Infections in the splenectomized patient
Infections in the diabetic patient
Infections in the alcoholic patient
Infections in the injection drug patient

Infections of the soft tissues and musculoskeletal system
Cellulitis and soft tissue infections, particularly:
Erisipelas
Gas gangrene
Necrotizing fasciitis
Primitive septic arthritis and on media
Primary osteomyelitis and on synthetic media
Spondylodiscitis

Infections of the cardiovascular system
Infective endocarditis
Etiology
Clinical manifestations and complications
Diagnosis (Dukes' criteria)
Principles of therapy and prophylaxis
Infectious myocarditis and pericarditis
Clinical manifestations and complications
Principles of diagnosis

Urinary tract infections and sexually transmitted diseases
Cystitis
Pyelonephritis
Syphilis
Gonorrhea
Chlamydia and pelvic inflammatory disease (PID)
Trichomonas
Gardrenella
Lymphogranuloma venereum

Infections of the nervous system
Meningitis
Etiology
Pathogenesis
Clinical manifestations
Diagnosis (clinical and laboratory, with emphasis on CSF analysis)
Principles of therapy
Encephalitis and encephalomyelitis
General pathogenesis
Clinical manifestations
Diagnostic evaluation
Main etiologic agents and their clinical features
HSV and VZV
CMV
Enterovirus
rabies
Bacterial toxin-mediated neuraxitis
Brain abscess and subdural empyema
Prerequisites for admission
No prior knowledge is required
Teaching methods
Formal teaching (32 hours):
frontal didactics 24 hours
Innovative asynchronous didactics: 8 hours (dedicated to student study of articles uploaded to MyAriel and presented during frontal classroom teaching)

Non-formal didactics (16 hours):
clinical case presentations
Teaching Resources
"Malattie Infettive" di Moroni, Esposito, Antinori
"Principles and Practice of Infectious Diseases" Mandell, Douglas and Bennett's
Assessment methods and Criteria
Admission to the examination is subject to attending at least 66 percent of the classes.
The examination will include a written test (multiple-choice quizzes) and an oral test.

Multiple-choice quiz No. 30 questions in 30 minutes.
Evaluation to access the oral test 18/30
The result of the written test does not average with the final grade.

There are no scheduled:
Intermediate tests
Pre-appeals
Useful materials for taking the test

The results of the written test will be communicated to students in the classroom after the written exam has been corrected and before the oral exam begins.
MED/17 - INFECTIOUS DISEASES - University credits: 5
Informal teaching: 16 hours
Lessons: 48 hours
Professor: Antinori Spinello
Shifts:
Turno
Professor: Antinori Spinello

Linea San Giuseppe

Course syllabus
Exanthematous infections
Epidemiology
Etiology
Pathogenesis and clinic (typical course and complications)
Therapeutic possibilities
Active and passive prophylaxis
of the following exanthematous diseases: measles, rubella, infectious megaloerythema, critical exanthema, scarlet fever, varicella, and other vesicular exanthema

Infections of the respiratory system
Infectious syndromes of the respiratory system:
Diphtheria
Pharyngitis/tonsillitis
Epiglottitis/laryngitis/tracheitis
Acute bronchitis and flare-ups of chronic bronchitis
Bronchiolitis
Viral pneumonias
Bacterial pneumonias
Influenza
Pulmonary tuberculosis (and extrapulmonary forms)
Whooping cough

Liver and biliary tract infections
Epidemiology, etiology, and pathogenesis of viral hepatitis
Diagnosis of acute and chronic viral hepatitis
Therapy of viral hepatitis
Yellow fever
Leptospirosis
Hydatidosis
Biliary tract infections

Infections of the digestive tract: infectious diarrheas
Etiological and pathophysiological classification
Food poisoning (staphylococcal, botulism, C. perfrigens, V. parahaemoliticus, B. cereus)
Viral gastroenteritis (Norwalk, Rotavirus, other viruses involved)
Bacterial gastroenteritis (Cholera, E.coli, minor salmonellosis, Shigella, Campylobacter, C. difficile)
Protozoal diarrheas (giardiasis, amebiasis, cryptosporidiosis)
Helminth diarrheas (tapeworm, oxyuriasis, ascaridiasis)

Tropical Diseases
Epidemiology of tropical diseases: what are the 6 "deadly killers"?
Malaria
Epidemiology
Life cycle
Pathogenesis
Typical and atypical presentation
Complications and prognosis
Diagnosis
Differential diagnosis between plasmodia
Principles of therapy and prophylaxis
Schistosomiasis
Epidemiology
Life cycle
Clinical: acute form, chronic forms
Diagnosis
Therapy
Control measures

Arthropod-borne infections
Dengue
West-Nile fever
Zika virus
Chikungunya
Viral hemorrhagic fevers
Rickettsiosis exanthema and ehrlichiosis

Systemic infections
Infectious mononucleosis and CMV infection
Brucellosis
Cutaneous and visceral leishmaniasis
Lyme diseases
Toxoplasmosis
Atypical mycobacterioses

Sepsis and septic shock
Etiology and epidemiology
Pathophysiology and pathogenesis
Clinical framing
The microbiological diagnosis
The antibiotic and supportive therapeutic approach

HIV infection
History
Epidemiology
Life cycle of HIV
Natural history of infection
Immunopathogenesis
Main opportunistic manifestations, divided by systems
Diagnosis of acute and chronic infection
Infections of the immunocompromised host
Infections in the solid organ transplant patient
Infections in the patient with bone marrow transplantation
Infections in the patient with neoplasia
Infections in the splenectomized patient
Infections in the diabetic patient
Infections in the alcoholic patient
Infections in the injection drug patient

Infections of the soft tissues and musculoskeletal system
Cellulitis and soft tissue infections, particularly:
Erisipelas
Gas gangrene
Necrotizing fasciitis
Primitive septic arthritis and on media
Primary osteomyelitis and on synthetic media
Spondylodiscitis

Infections of the cardiovascular system
Infective endocarditis
Etiology
Clinical manifestations and complications
Diagnosis (Dukes' criteria)
Principles of therapy and prophylaxis
Infectious myocarditis and pericarditis
Clinical manifestations and complications
Principles of diagnosis

Urinary tract infections and sexually transmitted diseases
Cystitis
Pyelonephritis
Syphilis
Gonorrhea
Chlamydia and pelvic inflammatory disease (PID)
Trichomonas
Gardrenella
Lymphogranuloma venereum

Infections of the nervous system
Meningitis
Etiology
Pathogenesis
Clinical manifestations
Diagnosis (clinical and laboratory, with emphasis on CSF analysis)
Principles of therapy
Encephalitis and encephalomyelitis
General pathogenesis
Clinical manifestations
Diagnostic evaluation
Main etiologic agents and their clinical features
HSV and VZV
CMV
Enterovirus
rabies
Bacterial toxin-mediated neuraxitis
Brain abscess and subdural empyema
Prerequisites for admission
No prior knowledge is required
Teaching methods
Formal teaching (32 hours):
frontal didactics 24 hours
Innovative asynchronous didactics: 8 hours (dedicated to student study of articles uploaded to MyAriel and presented during frontal classroom teaching)

Non-formal didactics (16 hours):
clinical case presentations
Teaching Resources
"Malattie Infettive" di Moroni, Esposito, Antinori
"Principles and Practice of Infectious Diseases" Mandell, Douglas and Bennett's
Assessment methods and Criteria
Admission to the examination is subject to attending at least 66 percent of the classes.
The examination will include a written test (multiple-choice quizzes) and an oral test.

Multiple-choice quiz No. 30 questions in 30 minutes.
Evaluation to access the oral test 18/30
The result of the written test does not average with the final grade.

There are no scheduled:
Intermediate tests
Pre-appeals
Useful materials for taking the test

The results of the written test will be communicated to students in the classroom after the written exam has been corrected and before the oral exam begins.
MED/17 - INFECTIOUS DISEASES - University credits: 5
Informal teaching: 16 hours
Lessons: 48 hours
Professor: Riva Agostino