Human Pathology (3rd year)
A.Y. 2024/2025
Learning objectives
The course aims to provide students with the tools:
· to learn the pathological basis of the diseases of the various organs and systems;
· to be able to integrate macroscopic, microscopic (histological and cytological) and molecular alterations in the specific clinical context;
· to correctly understand the pathological "report", in its entirety and with its clinical implications.
The course will also describe the main diagnostic procedures in surgical pathology, the professional skills, responsibilities and areas of activity of the pathologist.
· to learn the pathological basis of the diseases of the various organs and systems;
· to be able to integrate macroscopic, microscopic (histological and cytological) and molecular alterations in the specific clinical context;
· to correctly understand the pathological "report", in its entirety and with its clinical implications.
The course will also describe the main diagnostic procedures in surgical pathology, the professional skills, responsibilities and areas of activity of the pathologist.
Expected learning outcomes
At the end of the course, the student has to know:
· the pathological basis of the diseases of the various organs and systems;
· the most important diagnostic approaches of pathology (exfoliative and aspiration cytology, histology, frozen sections) and the techniques (immunohistochemistry and molecular pathology);
· possible applications of these diagnostic approaches in preventive medicine (cytological and molecular screening) and in the evaluation of prognostic and predictive parameters;
· how to correctly understand and integrate the information provided by the pathology report in the clinic for an adequate therapeutic decision-making process.
· the pathological basis of the diseases of the various organs and systems;
· the most important diagnostic approaches of pathology (exfoliative and aspiration cytology, histology, frozen sections) and the techniques (immunohistochemistry and molecular pathology);
· possible applications of these diagnostic approaches in preventive medicine (cytological and molecular screening) and in the evaluation of prognostic and predictive parameters;
· how to correctly understand and integrate the information provided by the pathology report in the clinic for an adequate therapeutic decision-making process.
Lesson period: year
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Course syllabus
Introduction to Anatomic Pathology
General principles of histopathology, cytopathology and autopsies.
Ancillary techniques in surgical pathology (imunohistochemistry, FISH and others molecular techniques)
General principles of diagnostic histopathology (pathological growth: metaplasia, dysplasia; tumor grading, tumor staging; the pathology report; prognostic and predictive markers)
Cardiovascular pathology
Pathology of the vessels: Arteriosclerosis, Atherosclerosis, Aneurysms and Dissection, Vascular Tumors
Heart Failure
Congenital Heart Disease
Ischemic Heart Disease
Valvular Heart Disease
Cardiomyopathies
Pericardial Disease
Cardiac Transplantation
Pathology of the lung and pleura
Congenital Anomalies, Atelectasis (Collapse), Pulmonary Edema
Acute Lung Injury and Acute Respiratory Distress Syndrome (Diffuse Alveolar Damage)
Obstructive and Restrictive Lung Diseases
Chronic Diffuse Interstitial (Restrictive) Diseases
Pulmonary Infections
Lung Transplantation
Tumors of the lung
Pleural Effusion
Pleural Tumors
General principles of histopathology, cytopathology and autopsies.
Ancillary techniques in surgical pathology (imunohistochemistry, FISH and others molecular techniques)
General principles of diagnostic histopathology (pathological growth: metaplasia, dysplasia; tumor grading, tumor staging; the pathology report; prognostic and predictive markers)
Cardiovascular pathology
Pathology of the vessels: Arteriosclerosis, Atherosclerosis, Aneurysms and Dissection, Vascular Tumors
Heart Failure
Congenital Heart Disease
Ischemic Heart Disease
Valvular Heart Disease
Cardiomyopathies
Pericardial Disease
Cardiac Transplantation
Pathology of the lung and pleura
Congenital Anomalies, Atelectasis (Collapse), Pulmonary Edema
Acute Lung Injury and Acute Respiratory Distress Syndrome (Diffuse Alveolar Damage)
Obstructive and Restrictive Lung Diseases
Chronic Diffuse Interstitial (Restrictive) Diseases
Pulmonary Infections
Lung Transplantation
Tumors of the lung
Pleural Effusion
Pleural Tumors
Prerequisites for admission
To attend the exam the student must have passed the exam of General Pathology and Physiopathology. To successfully face the course the student must have knowledge provided by previous teachings of Human Anatomy, Histology and Embriology, General Pathology and Physiopathology, Human Physiology and Biology and Genetics.
Teaching methods
Each credit includes hours of frontal and innovative teaching. The innovative teaching activities consist in the deepening of specific topics of the course syllabus, that will be selected by the students and the teacher. Such activity will be carried out in active collaboration between students and teacher.
The course includes 2 CFU of synchronous learning in the III year, 2 CFU of synchronous learning in the IV year 2 and 6 CFU in the V year, of which 5 of synchronous learning and 1 unsynchronous learning.
Unsynchronous learning will be mainly articulated through the methodology of work in small groups and particular attention will be given to the development of clinical-pathological reasoning, the application of a correct diagnostic algorithm, the development of correct differential diagnosis on the basis of emerged evidences, and the correct interpretation of the pathological reports.
The course includes 2 CFU of synchronous learning in the III year, 2 CFU of synchronous learning in the IV year 2 and 6 CFU in the V year, of which 5 of synchronous learning and 1 unsynchronous learning.
Unsynchronous learning will be mainly articulated through the methodology of work in small groups and particular attention will be given to the development of clinical-pathological reasoning, the application of a correct diagnostic algorithm, the development of correct differential diagnosis on the basis of emerged evidences, and the correct interpretation of the pathological reports.
Teaching Resources
Pelosi G, Sapino A, Maiorano E. Manual of Functional Pathological Anatomy. Minerva Medica Editions, 2022.
Strayer D.S., Rubin Emanuel. "General Pathology. Pathological anatomy". Piccin New Library, latest edition
Kumar V, Abbas A.K., J.C. Aster. "Robbins & Cotran. Pathological Anatomy". EDRA, latest edition
Additional learning material (pptx presentation, pdf ), will be made available during the course.
Strayer D.S., Rubin Emanuel. "General Pathology. Pathological anatomy". Piccin New Library, latest edition
Kumar V, Abbas A.K., J.C. Aster. "Robbins & Cotran. Pathological Anatomy". EDRA, latest edition
Additional learning material (pptx presentation, pdf ), will be made available during the course.
Assessment methods and Criteria
The exam consists of two "in itinere" oral tests, at the end of the III and IV years respectively, and an oral test at the end of the V year.
The student's ability will be valuated to:
a) clearly and comprehensively define the pathological basis of the different human diseases;
b) decide appropriately how and when to request a pathological examination in the patient's therapy, care and follow-up process;
c) correctly use the diagnostic algorithm of the various pathological investigations available, based on the knowledge of their cost / benefit ratio;
d) carry out and adequately send the samples taken from the patient to the pathologist;
e) correctly understand the pathology report.
Passing the test will result in a mark expressed out of thirty.
The student's ability will be valuated to:
a) clearly and comprehensively define the pathological basis of the different human diseases;
b) decide appropriately how and when to request a pathological examination in the patient's therapy, care and follow-up process;
c) correctly use the diagnostic algorithm of the various pathological investigations available, based on the knowledge of their cost / benefit ratio;
d) carry out and adequately send the samples taken from the patient to the pathologist;
e) correctly understand the pathology report.
Passing the test will result in a mark expressed out of thirty.
MED/08 - PATHOLOGY - University credits: 2
Lessons: 16 hours
: 8 hours
: 8 hours
Professors:
Falleni Monica, Gianelli Umberto
Shifts:
Professor(s)