Biology and Genetics

The course aims to provide basic knowledge of:
- the structure and function of the macromolecules depositary of genetic information;
- the molecular basis of the expression of genetic information and its regulation;
- the mechanisms that control cell differentiation;
- the concepts of continuity and variability of genetic information in living organisms;
- the mode of transmission of hereditary characters and the mechanisms that can give rise to phenotypic variants in humans;
- the methodology of genetic analysis and its usefulness in medical practice
- the basic concepts of descriptive and inferential statistic and the basic concepts of probability theory.

· The student should be able to demonstrate adequate knowledge and understanding of the basic concepts of cellular and molecular biology.
· The student should be able to accurately describe the eukaryotic cell both morphologically and functionally. In particular, he must have acquired sufficient knowledge to explain the mechanisms of organization, expression and transmission of genetic information and the biological variability induced by mutations and the recombination process.
· The student should be able to make assumptions based on experimental data provided in the form of biological problems
· The student should be able to interpret and adequately translate the possible applications of the acquired biological knowledge in the medical field
· the student shold be able to integrate the acquired knowledge to explain the existing structure / function relationship for each component or cellular compartment and their application in the various biological systems and disease models
· The student should be able to make assumptions based on genetic data provided in the form of pedigrees or allele frequencies
· The student should be able to expose and explain, in a simple but rigorous way, the biological processes that are the basis of life.
· The student must be able to read, interpret and critically comment on a scientific article
· The student should be able to interpret statistical descriptive analysis and to apply probability methods to solve practical problems