Analytics for Chemical Industry
A.Y. 2024/2025
Learning objectives
- Define analytical chemistry and the criteria that distinguish it from other sciences.
- Evaluate contemporary techniques and specialized situations in which the analyst will have to provide analytical solutions.
- Determine the solution of complex analytical problems using an integrated approach.
- Examine the analytical process in a systematic manner and emphasize the purpose of each stage.
- Provide the rationale for the use of statistics in chemical analysis and experimental design and the skills required to perform statistical testing and interpretation of chemical data manually.
- Introduce students to the planning and development of quality systems in the analytical laboratory.
- Evaluate contemporary techniques and specialized situations in which the analyst will have to provide analytical solutions.
- Determine the solution of complex analytical problems using an integrated approach.
- Examine the analytical process in a systematic manner and emphasize the purpose of each stage.
- Provide the rationale for the use of statistics in chemical analysis and experimental design and the skills required to perform statistical testing and interpretation of chemical data manually.
- Introduce students to the planning and development of quality systems in the analytical laboratory.
Expected learning outcomes
- Introduce students to strategies, techniques and efficiency of modern processes in analytical chemistry.
- Propose a suitable analytical approach, collect experimental data from measurements and then perform suitable arithmetic statistical calculations on these chemical data to solve straight-forward problems.
- Discuss the role of the analytical scientist in the analytical process and the significance of timely and appropriate analytical measurements to the reputation and economic well-being of a business.
- Demonstrate an understanding of the importance of quality management systems relating to the analytical laboratory.
- Discuss ways in which advanced techniques (alone or in combination) can be used to solve real industrial problems.
- Critically evaluate personal performance, justify choice of solution or strategy, and demonstrate innovation in the critical comparison of alternative approaches for solving the problem.
- Propose a suitable analytical approach, collect experimental data from measurements and then perform suitable arithmetic statistical calculations on these chemical data to solve straight-forward problems.
- Discuss the role of the analytical scientist in the analytical process and the significance of timely and appropriate analytical measurements to the reputation and economic well-being of a business.
- Demonstrate an understanding of the importance of quality management systems relating to the analytical laboratory.
- Discuss ways in which advanced techniques (alone or in combination) can be used to solve real industrial problems.
- Critically evaluate personal performance, justify choice of solution or strategy, and demonstrate innovation in the critical comparison of alternative approaches for solving the problem.
Lesson period: Second semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
Single session
Responsible
Lesson period
Second semester
Course syllabus
Fundamentals of Chemometrics (Multivariate analysis, Analysis of Variance (ANOVA), Design of experiments, Process optimization).
Industrial implementation of instrumental techniques i.e. spectroscopy, chromatography, electroanalysis, thermal analysis (TGA, DSC).
Chemical Process Analytics as Part of Quality Management and Quality Assurance in the analytical laboratory.
Laboratory accreditation. Process analytical chemistry and process control procedures. Analytical instrumentation and measurement techniques in process control.
Sampling of liquids and gases. On-line, at line, in-line, on field and remote analysis.
Integrated control networks. Fitting and scaling-up and fitting of analytical methodologies to industrial conditions.
Outlook on Research and Development Trends in Industrial Process and Product Analytics with discussion of some applicative cases.
Industrial implementation of instrumental techniques i.e. spectroscopy, chromatography, electroanalysis, thermal analysis (TGA, DSC).
Chemical Process Analytics as Part of Quality Management and Quality Assurance in the analytical laboratory.
Laboratory accreditation. Process analytical chemistry and process control procedures. Analytical instrumentation and measurement techniques in process control.
Sampling of liquids and gases. On-line, at line, in-line, on field and remote analysis.
Integrated control networks. Fitting and scaling-up and fitting of analytical methodologies to industrial conditions.
Outlook on Research and Development Trends in Industrial Process and Product Analytics with discussion of some applicative cases.
Prerequisites for admission
Knowledge of the fundamentals of analytical chemistry, mathematics and chemical physics.
Teaching methods
Classroom - taught lessons, seminars and exercises.
Teaching Resources
K.H. Koch, "Process Analytical Chemistry ", Springer, (1999), ISBN 978-3-540-65337-0
G.E.P. Box, J.S. Hunter and W.G. Hunter, "Statistics for experimenters: An introduction to design, data analysis and model building ", J. Wiley & Son, Chichester, (1978), ISBN 0471093157
J.N. Miller and J.C. Miller, "Statistics and Chemometrics for Analytical Chemistry", 6th Ed., Prentice Hall, (2010), ISBN-10 0273730428
R. de Levie, "How to use Excel in analytical chemistry and in general scientific data analysis", Cambridge Univ. Press, (2001). ISBN 0521644844
Beebe, K. R., Pell, R. J. &Seasholtz, M. B., "Chemometrics: A Practical Guide", John Wiley & Sons, Inc., (1998). ISBN-10 0471124516
D.C. Harris, "Quantitative Chemical Analysis", 8th Ed., Freeman, (2011), ISBN-10 1-4292-1815-0
G.D. Christian "Analytical Chemistry", 6th Ed., Wiley, (2004) ISBN 978-0-471-21472-4
E. Prichard, "Analytical Measurement Terminology", Royal Soc. Chem., (2000), ISBN 0854044432
J. Dean et al, "Practical Skills in Chemistry", Prentice Hall, (2002), ISBN 013028002X
Recommended reading:
M. Valcarel, "Principles of Analytical Chemistry: A Textbook", Springer, (2000), ISBN 354064007X
R. Kellner, J-M. Mermet, M. Otto, H.M. Widmer (Eds.), "Analytical Chemistry", 2nd Ed., Wiley-VCH, (2004), ISBN 978-3-527-30590-2
G.E.P. Box, J.S. Hunter and W.G. Hunter, "Statistics for experimenters: An introduction to design, data analysis and model building ", J. Wiley & Son, Chichester, (1978), ISBN 0471093157
J.N. Miller and J.C. Miller, "Statistics and Chemometrics for Analytical Chemistry", 6th Ed., Prentice Hall, (2010), ISBN-10 0273730428
R. de Levie, "How to use Excel in analytical chemistry and in general scientific data analysis", Cambridge Univ. Press, (2001). ISBN 0521644844
Beebe, K. R., Pell, R. J. &Seasholtz, M. B., "Chemometrics: A Practical Guide", John Wiley & Sons, Inc., (1998). ISBN-10 0471124516
D.C. Harris, "Quantitative Chemical Analysis", 8th Ed., Freeman, (2011), ISBN-10 1-4292-1815-0
G.D. Christian "Analytical Chemistry", 6th Ed., Wiley, (2004) ISBN 978-0-471-21472-4
E. Prichard, "Analytical Measurement Terminology", Royal Soc. Chem., (2000), ISBN 0854044432
J. Dean et al, "Practical Skills in Chemistry", Prentice Hall, (2002), ISBN 013028002X
Recommended reading:
M. Valcarel, "Principles of Analytical Chemistry: A Textbook", Springer, (2000), ISBN 354064007X
R. Kellner, J-M. Mermet, M. Otto, H.M. Widmer (Eds.), "Analytical Chemistry", 2nd Ed., Wiley-VCH, (2004), ISBN 978-3-527-30590-2
Assessment methods and Criteria
Oral group presentation (max 2 people per group) with detailed analysis of some industrial realities e.g. water quality control; air quality control; food quality control; drugs quality control.
CHIM/01 - ANALYTICAL CHEMISTRY - University credits: 6
Lessons: 48 hours
Professor:
Arnaboldi Serena
Shifts:
Turno
Professor:
Arnaboldi SerenaProfessor(s)