Clinical Biochemistry and Clinical Molecular Biology

The aim of the course is to provide students with knowledge and understanding of some of the methodologies useful in clinical and research laboratories that employ biochemical and enzymatic approaches useful in diagnostics and for the development of drugs and biotechnological products.
Specifically, the following will be treated:
- General concepts on biomarkers (choice of tissue to be analyzed, reference range, clinical sensitivity, clinical specificity)
-Strategies in the search for new biomarkers
The instrumentation (spectrophotometry, immunometry, mass spectrometry, polimerase chain reaction - PCR, quantitative PCR and next generation sequencing techniques) for the quantitative measurements of some biomarkers
-Biomarkers of hepatic, cardiac and renal diseases
-Examples of clinical cases

The learning outcomes of the students are evaluated by the teacher through an oral examination of learning based on the program carried out during the course.
The examination of the students by the teacher will mainly be aimed at assessing the knowledge and understanding of the basic methodologies for clinical analysis and the evaluation of the skills acquired by. In particular, the language properties used by the student will be assessed, as well as the skills acquired for the choice of the most suitable methodology to achieve the result.