Human Anatomy
A.Y. 2021/2022
Learning objectives
The aim of the Course of Neuroanatomy is to:
- Provide an overview of the ultrastructure of neurons and glia and the major cytoarchitectural features of the connections between neurons (brain barrier);
- Describe the difference between grey matter (e.g. nuclei, cortex and basal nuclei/ganglia) and white matter;
- Provide the morphological basis of the impulse transmission of neurons;
- Provide the basic features of the topography and structural organization of the forebrain (cerebral hemispheres), the midbrain (amygdala, thalamus, hypothalamus, hippocampus, pituitary gland), the brainstem/hindbrain (pons, medulla oblongata and cerebellum), with definition of sensitive and motor tracts and cortical areas;
- Describe the morphological features and the blood supply and venous drainage of the different organs so to deduce the impact of rupture and occlusion of the vessels;
- Describe the anatomical basis of the reflexes (myotatic, tendon an those involving cranial nerves), that are critical for clinical diagnosis and for the basic understanding of the principles of motor control;
- Describe the basic features of development of the nervous system and of the common malformations that occur in the nervous system;
- Obtain an understanding of the functional anatomy of sensory and motor processing and higher cerebral functions such as language and emotions and to be able to apply this knowledge to the clinical situation.
- Provide an overview of the ultrastructure of neurons and glia and the major cytoarchitectural features of the connections between neurons (brain barrier);
- Describe the difference between grey matter (e.g. nuclei, cortex and basal nuclei/ganglia) and white matter;
- Provide the morphological basis of the impulse transmission of neurons;
- Provide the basic features of the topography and structural organization of the forebrain (cerebral hemispheres), the midbrain (amygdala, thalamus, hypothalamus, hippocampus, pituitary gland), the brainstem/hindbrain (pons, medulla oblongata and cerebellum), with definition of sensitive and motor tracts and cortical areas;
- Describe the morphological features and the blood supply and venous drainage of the different organs so to deduce the impact of rupture and occlusion of the vessels;
- Describe the anatomical basis of the reflexes (myotatic, tendon an those involving cranial nerves), that are critical for clinical diagnosis and for the basic understanding of the principles of motor control;
- Describe the basic features of development of the nervous system and of the common malformations that occur in the nervous system;
- Obtain an understanding of the functional anatomy of sensory and motor processing and higher cerebral functions such as language and emotions and to be able to apply this knowledge to the clinical situation.
Expected learning outcomes
At the end of the Course of Neuroanatomy, the student should be able to:
- Demonstrate the knowledge and the understanding of the basic anatomy of the nervous system, also by using the radiological imaging;
- Have clearly understood the complexity and interconnectedness of the central nervous system;
- Apply the basic mechanisms of the development of the nervous system to the interpretation of the common malformations;
- Apply the knowledge of the neuroanatomy to the sensory and motor processing and higher cerebral functions such as language and emotions and also to apply this knowledge to the interpretation of the clinical situation, embracing imaging technology and especially the resulting images,
- Understand that the knowledge of the normal functions of nervous system components make possible that, when malfunction is observed, to work backward and determine which structure or structures are affected.
- Demonstrate the knowledge and the understanding of the basic anatomy of the nervous system, also by using the radiological imaging;
- Have clearly understood the complexity and interconnectedness of the central nervous system;
- Apply the basic mechanisms of the development of the nervous system to the interpretation of the common malformations;
- Apply the knowledge of the neuroanatomy to the sensory and motor processing and higher cerebral functions such as language and emotions and also to apply this knowledge to the interpretation of the clinical situation, embracing imaging technology and especially the resulting images,
- Understand that the knowledge of the normal functions of nervous system components make possible that, when malfunction is observed, to work backward and determine which structure or structures are affected.
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
More specific information on the delivery modes of training activities for academic year 2021/22 will be provided over the coming months, based on the evolution of the public health situation.
Course syllabus
The third semester takes place in the second academic year and it focuses on central and peripheral nervous system, organs of special senses and corresponding embryology.
Description of the general features of nervous tissue, the spinal cord and the brain stem.
Introduction to the fundamentals of neural development.
Fundamental concepts, organizational principles, structure, connectivity, and how these relate to function and behavior are considered, with a strong emphasis on the clinical application of "traditional" neuroanatomical knowledge.
The forebrain (cerebral hemispheres), the midbrain (amygdala, thalamus, hypothalamus, hippocampus, pituitary gland, pineal gland and crus cerebri), the brainstem/hindbrain (pons, medulla oblongata and cerebellum).
Characteristics of the grey matter (e.g. nuclei, ganglia, cerebellar and cerebral cortex and basal nuclei/ganglia) and white matter (association, commissural and projection fibers, and the corpus callosum).
Cortical topography: frontal, parietal, temporal and occipital lobes and the major sulci/landmarks that separate them. Description of the cerebral cortex in relation to its functions, namely: motor, sensory, visual, auditory, speech; memory and emotion, decision making, social behavior.
Describe the organization of the internal capsule.
Basal ganglia (the caudate nucleus, putamen, and globus pallidus, their relationship with each other and with the lateral ventricle and internal capsule).
Description of the cerebellar anatomy (anatomic division and evolutionary terms neocerebellum, paleocerebellum and pontocerebellum).
Description of the cerebellar cortex and nuclei, afferents, internal circuitry, efferents and blood supply.
Identify the major structures of the limbic system (limbic lobe, hypothalamus, hippocampus, amygdala.
Describe and identify the anatomic features of the hypothalamus, the efferent connections of the hypothalamus with the autonomic nervous system and compare neuroendocrine secretion and control in the anterior and posterior pituitary.
Description of the structure of the spinal cord, a typical spinal nerve and a reflex arc, and its relation to the vertebral column.
Spinal and dorsal column-medial lemnisci, trigeminal lemniscus (proprioception i.e., joint position, tactile discrimination, vibration sense and form recognition).
Motor tracts: pyramidal [the corticobulbar and corticospinal tracts) and extrapyramidal (i.e., reticulospinal, vestibulospinal, tectospinal, rubrospinal including the basal ganglia (caudate, putamen, and globus pallidus), and the subthalamic nucleus].
Description of the 12 cranial nerves and their major functions in relation to innervation.
Description of the general organization of the outer, middle and inner ear.
Description of the structure of the visual system: eye, eyelid, conjunctiva and lacrimal gland.
Particular importance is given to central nervous pathways and to the anatomical basis of the reflexes (Moro reflex, abdominal reflexes, myotatic, tendon and those involving cranial nerves like as pupillary light reflex, the lacrimal reflex , the cough reflex, sucking and swallowing reflexes, the gag reflex, salivation, accommodation and corneal reflexes, vestibulo-ocular reflex, baroreflex) that are critical for clinical diagnosis and also for the basic understanding of the principles of motor control.
Description of the structural differences between the three layers of meninges (dura, arachnoid and pia), their relationship to the brain and spinal cord and the ventricular system and the formation, circulation, drainage and role of cerebrospinal fluid.
Description of the general features of nervous tissue, the spinal cord and the brain stem.
Introduction to the fundamentals of neural development.
Fundamental concepts, organizational principles, structure, connectivity, and how these relate to function and behavior are considered, with a strong emphasis on the clinical application of "traditional" neuroanatomical knowledge.
The forebrain (cerebral hemispheres), the midbrain (amygdala, thalamus, hypothalamus, hippocampus, pituitary gland, pineal gland and crus cerebri), the brainstem/hindbrain (pons, medulla oblongata and cerebellum).
Characteristics of the grey matter (e.g. nuclei, ganglia, cerebellar and cerebral cortex and basal nuclei/ganglia) and white matter (association, commissural and projection fibers, and the corpus callosum).
Cortical topography: frontal, parietal, temporal and occipital lobes and the major sulci/landmarks that separate them. Description of the cerebral cortex in relation to its functions, namely: motor, sensory, visual, auditory, speech; memory and emotion, decision making, social behavior.
Describe the organization of the internal capsule.
Basal ganglia (the caudate nucleus, putamen, and globus pallidus, their relationship with each other and with the lateral ventricle and internal capsule).
Description of the cerebellar anatomy (anatomic division and evolutionary terms neocerebellum, paleocerebellum and pontocerebellum).
Description of the cerebellar cortex and nuclei, afferents, internal circuitry, efferents and blood supply.
Identify the major structures of the limbic system (limbic lobe, hypothalamus, hippocampus, amygdala.
Describe and identify the anatomic features of the hypothalamus, the efferent connections of the hypothalamus with the autonomic nervous system and compare neuroendocrine secretion and control in the anterior and posterior pituitary.
Description of the structure of the spinal cord, a typical spinal nerve and a reflex arc, and its relation to the vertebral column.
Spinal and dorsal column-medial lemnisci, trigeminal lemniscus (proprioception i.e., joint position, tactile discrimination, vibration sense and form recognition).
Motor tracts: pyramidal [the corticobulbar and corticospinal tracts) and extrapyramidal (i.e., reticulospinal, vestibulospinal, tectospinal, rubrospinal including the basal ganglia (caudate, putamen, and globus pallidus), and the subthalamic nucleus].
Description of the 12 cranial nerves and their major functions in relation to innervation.
Description of the general organization of the outer, middle and inner ear.
Description of the structure of the visual system: eye, eyelid, conjunctiva and lacrimal gland.
Particular importance is given to central nervous pathways and to the anatomical basis of the reflexes (Moro reflex, abdominal reflexes, myotatic, tendon and those involving cranial nerves like as pupillary light reflex, the lacrimal reflex , the cough reflex, sucking and swallowing reflexes, the gag reflex, salivation, accommodation and corneal reflexes, vestibulo-ocular reflex, baroreflex) that are critical for clinical diagnosis and also for the basic understanding of the principles of motor control.
Description of the structural differences between the three layers of meninges (dura, arachnoid and pia), their relationship to the brain and spinal cord and the ventricular system and the formation, circulation, drainage and role of cerebrospinal fluid.
Prerequisites for admission
Students must have got a basic knowledge of Cytology, Histology and Cellular Biology.
To take the oral exam, the student must have passed the exam of Histology and Microscopic Anatomy.
To take the oral exam, the student must have passed the exam of Histology and Microscopic Anatomy.
Teaching methods
During the three semesters of the Course of Anatomy, eight multiple choice tests on specific topics are submitted to the students to assess the basic knowledge and the preparation of the students on the key concepts of the different subjects.
Each multiple choice test (MCT) is based on forty questions with five possible answers for every question.
The correction of the MCT is a machine-readable and fully-automated procedure.
After each test, students receive formative feedback for their overall score (positive or negative), including a detailed breakdown of their performance.
At the end of the course:
- the student who passed all the eight multiple choice tests will be directly admitted to an oral exam including the arguments of the Course. This "major bonus" can be exploited only time during the exam dates of the corresponding academic year. If the student fails in the oral exam, he/she should attend a new MCT including all the arguments of the program Course
- the student who have not passed only one MCT should attend a new MCT including the arguments related to the failed test. This "minor bonus" can be exploited only time during the exam dates of the corresponding academic year, even in the case of a period of multiple exam session.
- the student who have not passed two (or more) MCT should attend a new MCT including all the arguments of the program Course to be admitted to the oral exam.
Oral exam:
- it consists of an oral interview on the whole program. The oral exam must be carried out at the same time of the session in which the preliminary written test is taken.
Each multiple choice test (MCT) is based on forty questions with five possible answers for every question.
The correction of the MCT is a machine-readable and fully-automated procedure.
After each test, students receive formative feedback for their overall score (positive or negative), including a detailed breakdown of their performance.
At the end of the course:
- the student who passed all the eight multiple choice tests will be directly admitted to an oral exam including the arguments of the Course. This "major bonus" can be exploited only time during the exam dates of the corresponding academic year. If the student fails in the oral exam, he/she should attend a new MCT including all the arguments of the program Course
- the student who have not passed only one MCT should attend a new MCT including the arguments related to the failed test. This "minor bonus" can be exploited only time during the exam dates of the corresponding academic year, even in the case of a period of multiple exam session.
- the student who have not passed two (or more) MCT should attend a new MCT including all the arguments of the program Course to be admitted to the oral exam.
Oral exam:
- it consists of an oral interview on the whole program. The oral exam must be carried out at the same time of the session in which the preliminary written test is taken.
Teaching Resources
- Anatomia del Gray - Le basi anatomiche per la pratica clinica - di Gray - Susan Stranding · 2017
- Trattato di Anatomia Umana e Anatomia Topografica - Anatomy Bag e Risorse Digitali su Piattaforma Virtual Campus di Anastasi et al, Ed 2019
- Lo sviluppo prenatale dell'uomo. Embriologia ad orientamento clinico (Italiano X Ed.) 2017 di Keith L. Moore, T. V. Persaud, Mark G. Torchia
- Neuroanatomia nel contesto clinico - Atlante Strutture, sezioni, sistemi e sindromi 9a Edizione americana, Autore/i Duane E. Haines, Edizione italiana a cura di Maurizio Vertemati
- Fitzgerald - Neuroanatomia con riferimenti funzionali e clinici (VII Ed), Mtui E., Gruener G., Dockery P.
- Netter Atlante di Anatomia Umana VI Ed, di Netter F.H.
- Trattato di Anatomia Umana e Anatomia Topografica - Anatomy Bag e Risorse Digitali su Piattaforma Virtual Campus di Anastasi et al, Ed 2019
- Lo sviluppo prenatale dell'uomo. Embriologia ad orientamento clinico (Italiano X Ed.) 2017 di Keith L. Moore, T. V. Persaud, Mark G. Torchia
- Neuroanatomia nel contesto clinico - Atlante Strutture, sezioni, sistemi e sindromi 9a Edizione americana, Autore/i Duane E. Haines, Edizione italiana a cura di Maurizio Vertemati
- Fitzgerald - Neuroanatomia con riferimenti funzionali e clinici (VII Ed), Mtui E., Gruener G., Dockery P.
- Netter Atlante di Anatomia Umana VI Ed, di Netter F.H.
Assessment methods and Criteria
The final exam (oral) is held at the end of the Macroscopic Human Morphology Course which takes place in three semesters: first and second semester of the first year and first semester of the second year.
To pass the exam, which validates the acquisition of the credits attributed to the Course, the following tests must be passed:
- Preliminary written test, preparatory to admission to the oral test: it consists of answering a set of multiple-choice quizzes relating to the entire exam program (except for students who have passed the ongoing test on the Locomotor System described below), distributed among the various topics in proportion to their relevance. For this test 40 quizzes are provided, each comprising five answers that can be true or false independently of each other. The correction is carried out automatically, by optical reading of a form filled in by the candidates.
Passing the quiz test allows, in the same session and only in that one, access to the oral exam. If the oral exam is not passed, the student must take the quiz test again, even in the case of sessions with more than one exam.
The test lasts 90 minutes.
The test is considered passed when the condition is satisfied:
t = 5 * N - e ≥ 46 where:
- N = number of quizzes in which all five questions were answered correctly
- e = number of incorrect questions.
N= 14 15 16 17 18 19 20
e≤ 20 25 30 35 40 45 50
- Oral exam: it consists of an interview on the topics of the entire program, namely Locomotor (except for students who have passed the ongoing test on the Locomotor System as described below), Splanchnology, Neuroanatomy, Embryology, Topographic Anatomy. The oral exam must be carried out within the same exam datein which the preliminary quiz test is taken.
If the student who has passed the ongoing test on the Locomotor System does not pass the oral exam, the ongoing test validity will expire for the remaining session, hence the student will have to take the quiz on the whole course program before trying again the oral exam
There is an optional ongoing test concerning the Locomotor System (Generalities, Bones, Joints and Muscles). For this test 40 quizzes are provided, each comprising five answers that can be true or false independently of each other. The correction is carried out automatically, by optical reading of a form filled in by the candidates.
This ongoing test will be taken at the beginning of the first semester of the second year and, in any case, notified in advance to students.
The test is considered passed when the condition is satisfied:
t = 5 * N - e ≥ 46 where:
- N = number of quizzes in which all five questions were answered correctly
- e = number of incorrect questions.
N= 14 15 16 17 18 19 20
e≤ 20 25 30 35 40 45 50
The test lasts 60 minutes.
Passing the test allows the exemption of the part concerning the arguments of Locomotor System from the preliminary quiz test and from the oral exam.
The validity of this ongoing test is for all exam sessions (7) subsequent to the end of the Course and relative to the current academic year.
To pass the exam, which validates the acquisition of the credits attributed to the Course, the following tests must be passed:
- Preliminary written test, preparatory to admission to the oral test: it consists of answering a set of multiple-choice quizzes relating to the entire exam program (except for students who have passed the ongoing test on the Locomotor System described below), distributed among the various topics in proportion to their relevance. For this test 40 quizzes are provided, each comprising five answers that can be true or false independently of each other. The correction is carried out automatically, by optical reading of a form filled in by the candidates.
Passing the quiz test allows, in the same session and only in that one, access to the oral exam. If the oral exam is not passed, the student must take the quiz test again, even in the case of sessions with more than one exam.
The test lasts 90 minutes.
The test is considered passed when the condition is satisfied:
t = 5 * N - e ≥ 46 where:
- N = number of quizzes in which all five questions were answered correctly
- e = number of incorrect questions.
N= 14 15 16 17 18 19 20
e≤ 20 25 30 35 40 45 50
- Oral exam: it consists of an interview on the topics of the entire program, namely Locomotor (except for students who have passed the ongoing test on the Locomotor System as described below), Splanchnology, Neuroanatomy, Embryology, Topographic Anatomy. The oral exam must be carried out within the same exam datein which the preliminary quiz test is taken.
If the student who has passed the ongoing test on the Locomotor System does not pass the oral exam, the ongoing test validity will expire for the remaining session, hence the student will have to take the quiz on the whole course program before trying again the oral exam
There is an optional ongoing test concerning the Locomotor System (Generalities, Bones, Joints and Muscles). For this test 40 quizzes are provided, each comprising five answers that can be true or false independently of each other. The correction is carried out automatically, by optical reading of a form filled in by the candidates.
This ongoing test will be taken at the beginning of the first semester of the second year and, in any case, notified in advance to students.
The test is considered passed when the condition is satisfied:
t = 5 * N - e ≥ 46 where:
- N = number of quizzes in which all five questions were answered correctly
- e = number of incorrect questions.
N= 14 15 16 17 18 19 20
e≤ 20 25 30 35 40 45 50
The test lasts 60 minutes.
Passing the test allows the exemption of the part concerning the arguments of Locomotor System from the preliminary quiz test and from the oral exam.
The validity of this ongoing test is for all exam sessions (7) subsequent to the end of the Course and relative to the current academic year.
BIO/16 - HUMAN ANATOMY - University credits: 5
Lessons: 60 hours
Professors:
Moscheni Claudia, Vertemati Maurizio
Professor(s)